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P54066

- RL7A_METJA

UniProt

P54066 - RL7A_METJA

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Protein
50S ribosomal protein L7Ae
Gene
rpl7ae, MJ1203
Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.UniRule annotation

GO - Molecular functioni

  1. protein binding Source: IntAct
  2. rRNA binding Source: UniProtKB-KW
  3. ribonuclease P activity Source: UniProtKB-HAMAP
  4. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. ribosome biogenesis Source: InterPro
  2. tRNA 5'-leader removal Source: UniProtKB-HAMAP
  3. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L7Ae
Alternative name(s):
Ribosomal protein L8e
Gene namesi
Name:rpl7ae
Ordered Locus Names:MJ1203
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
ProteomesiUP000000805: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. ribosome Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11711750S ribosomal protein L7AeUniRule annotation
PRO_0000136793Add
BLAST

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Probably part of the RNase P complex By similarity.

Binary interactionsi

WithEntry#Exp.IntActNotes
MJ0694Q581054EBI-2944269,EBI-2944259

Protein-protein interaction databases

IntActiP54066. 2 interactions.
STRINGi243232.MJ1203.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi11 – 2212
Beta strandi25 – 306
Helixi31 – 399
Beta strandi44 – 507
Helixi55 – 573
Turni58 – 603
Helixi61 – 677
Beta strandi72 – 765
Helixi78 – 847
Beta strandi92 – 987
Helixi102 – 11514

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1RA4X-ray1.86A1-117[»]
1SDSX-ray1.80A/B/C1-117[»]
1XBIX-ray1.45A1-117[»]
3PAFX-ray1.70A/B1-117[»]
ProteinModelPortaliP54066.
SMRiP54066. Positions 1-117.

Miscellaneous databases

EvolutionaryTraceiP54066.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1358.
KOiK02936.
OMAiWIQASQP.
PhylomeDBiP54066.

Family and domain databases

Gene3Di3.30.1330.30. 1 hit.
HAMAPiMF_00326. Ribosomal_L7Ae_Arch.
InterProiIPR029064. L30e-like.
IPR004038. Ribosomal_L7Ae/L30e/S12e/Gad45.
IPR018492. Ribosomal_L7Ae/L8/Nhp2.
IPR022481. Ribosomal_L7Ae_arc.
IPR004037. Ribosomal_L7Ae_CS.
IPR000948. Ribosomal_L7Ae_prok.
[Graphical view]
PfamiPF01248. Ribosomal_L7Ae. 1 hit.
[Graphical view]
PRINTSiPR00881. L7ARS6FAMILY.
PR00884. RIBOSOMALHS6.
SUPFAMiSSF55315. SSF55315. 1 hit.
TIGRFAMsiTIGR03677. rpl7ae. 1 hit.
PROSITEiPS01082. RIBOSOMAL_L7AE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P54066-1 [UniParc]FASTAAdd to Basket

« Hide

MAVYVKFKVP EEIQKELLDA VAKAQKIKKG ANEVTKAVER GIAKLVIIAE    50
DVKPEEVVAH LPYLCEEKGI PYAYVASKQD LGKAAGLEVA ASSVAIINEG 100
DAEELKVLIE KVNVLKQ 117
Length:117
Mass (Da):12,686
Last modified:July 15, 1998 - v2
Checksum:i7CAB706F09371BA6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L77117 Genomic DNA. Translation: AAB99207.1.
RefSeqiNP_248198.1. NC_000909.1.

Genome annotation databases

EnsemblBacteriaiAAB99207; AAB99207; MJ_1203.
GeneIDi1452098.
KEGGimja:MJ_1203.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L77117 Genomic DNA. Translation: AAB99207.1 .
RefSeqi NP_248198.1. NC_000909.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1RA4 X-ray 1.86 A 1-117 [» ]
1SDS X-ray 1.80 A/B/C 1-117 [» ]
1XBI X-ray 1.45 A 1-117 [» ]
3PAF X-ray 1.70 A/B 1-117 [» ]
ProteinModelPortali P54066.
SMRi P54066. Positions 1-117.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi P54066. 2 interactions.
STRINGi 243232.MJ1203.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAB99207 ; AAB99207 ; MJ_1203 .
GeneIDi 1452098.
KEGGi mja:MJ_1203.

Phylogenomic databases

eggNOGi COG1358.
KOi K02936.
OMAi WIQASQP.
PhylomeDBi P54066.

Miscellaneous databases

EvolutionaryTracei P54066.

Family and domain databases

Gene3Di 3.30.1330.30. 1 hit.
HAMAPi MF_00326. Ribosomal_L7Ae_Arch.
InterProi IPR029064. L30e-like.
IPR004038. Ribosomal_L7Ae/L30e/S12e/Gad45.
IPR018492. Ribosomal_L7Ae/L8/Nhp2.
IPR022481. Ribosomal_L7Ae_arc.
IPR004037. Ribosomal_L7Ae_CS.
IPR000948. Ribosomal_L7Ae_prok.
[Graphical view ]
Pfami PF01248. Ribosomal_L7Ae. 1 hit.
[Graphical view ]
PRINTSi PR00881. L7ARS6FAMILY.
PR00884. RIBOSOMALHS6.
SUPFAMi SSF55315. SSF55315. 1 hit.
TIGRFAMsi TIGR03677. rpl7ae. 1 hit.
PROSITEi PS01082. RIBOSOMAL_L7AE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.
  2. "Structure of protein L7Ae bound to a K-turn derived from an archaeal box H/ACA sRNA at 1.8 A resolution."
    Hamma T., Ferre-D'Amare A.R.
    Structure 12:893-903(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS), RNA-BINDING.
  3. "The crystal structure of the Methanocaldococcus jannaschii multifunctional L7Ae RNA-binding protein reveals an induced-fit interaction with the box C/D RNAs."
    Suryadi J., Tran E.J., Maxwell E.S., Brown B.A. II
    Biochemistry 44:9657-9672(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.45 ANGSTROMS).

Entry informationi

Entry nameiRL7A_METJA
AccessioniPrimary (citable) accession number: P54066
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: July 15, 1998
Last modified: July 9, 2014
This is version 92 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Methanococcus jannaschii
    Methanococcus jannaschii: entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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