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P54049

- RL10_METJA

UniProt

P54049 - RL10_METJA

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Protein
50S ribosomal protein L10
Gene
rpl10, rplP0, MJ0509
Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors Inferred.UniRule annotation

GO - Molecular functioni

  1. large ribosomal subunit rRNA binding Source: UniProtKB-HAMAP
  2. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. ribosome biogenesis Source: InterPro
  2. translational elongation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L10
Alternative name(s):
Acidic ribosomal protein P0 homolog
MjaL10
Gene namesi
Name:rpl10
Synonyms:rplP0
Ordered Locus Names:MJ0509
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
ProteomesiUP000000805: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. ribosome Source: UniProtKB-KW
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 33833850S ribosomal protein L10UniRule annotation
PRO_0000154793Add
BLAST

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion Inferred.

Protein-protein interaction databases

STRINGi243232.MJ0509.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi11 – 2616
Beta strandi27 – 348
Helixi40 – 5011
Turni51 – 533
Beta strandi54 – 585
Helixi61 – 7414
Helixi78 – 869
Beta strandi89 – 9810
Helixi100 – 10910
Beta strandi112 – 1143
Beta strandi126 – 1283
Beta strandi130 – 1323
Helixi140 – 1467
Beta strandi151 – 1544
Beta strandi157 – 1604
Beta strandi164 – 1674
Helixi175 – 1839
Beta strandi189 – 1924
Beta strandi194 – 2007
Beta strandi203 – 2053
Helixi207 – 2137

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3JSYX-ray1.60A/B10-221[»]
ProteinModelPortaliP54049.

Miscellaneous databases

EvolutionaryTraceiP54049.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0244.
KOiK02864.
OMAiWKKDEIE.
PhylomeDBiP54049.

Family and domain databases

Gene3Di1.10.10.380. 2 hits.
HAMAPiMF_00280. Ribosomal_L10_arch.
InterProiIPR022909. 50S_L10_arch.
IPR001790. Ribosomal_L10/acidic_P0.
IPR001813. Ribosomal_L10/L12.
IPR013522. Ribosomal_L10_N_arc.
[Graphical view]
PfamiPF00428. Ribosomal_60s. 1 hit.
PF00466. Ribosomal_L10. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P54049-1 [UniParc]FASTAAdd to Basket

« Hide

METKVKAHVA PWKIEEVKTL KGLIKSKPVV AIVDMMDVPA PQLQEIRDKI    50
RDKVKLRMSR NTLIIRALKE AAEELNNPKL AELANYVERG AAILVTDMNP 100
FKLYKLLEEN KSPAPVRGGQ IAPCDIKVEK GSTGMPPGPF LGELKSVGIP 150
AAIEKGKIAI KEDKVVVKKG EVVSPKLAAV LDRLGIKPIK VGLNILAVYE 200
DGIIYTPDVL KVDEEKLLAD IQAAYQNAFN LAFNTAYPAK EVLPFLIQKA 250
FINARALSVE TAFVTKETAG DILAKAQAQA LALASKLPDE ALDEDIKAKL 300
SSVEVSAAPA AEEEKEEEKK EEEKKEEDTG AAGLALLF 338
Length:338
Mass (Da):36,751
Last modified:July 15, 1998 - v2
Checksum:i63A6AFD357E3052D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L77117 Genomic DNA. Translation: AAB98499.1.
RefSeqiNP_247485.1. NC_000909.1.
WP_010870010.1. NC_000909.1.

Genome annotation databases

EnsemblBacteriaiAAB98499; AAB98499; MJ_0509.
GeneIDi1451371.
KEGGimja:MJ_0509.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L77117 Genomic DNA. Translation: AAB98499.1 .
RefSeqi NP_247485.1. NC_000909.1.
WP_010870010.1. NC_000909.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3JSY X-ray 1.60 A/B 10-221 [» ]
ProteinModelPortali P54049.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243232.MJ0509.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAB98499 ; AAB98499 ; MJ_0509 .
GeneIDi 1451371.
KEGGi mja:MJ_0509.

Phylogenomic databases

eggNOGi COG0244.
KOi K02864.
OMAi WKKDEIE.
PhylomeDBi P54049.

Miscellaneous databases

EvolutionaryTracei P54049.

Family and domain databases

Gene3Di 1.10.10.380. 2 hits.
HAMAPi MF_00280. Ribosomal_L10_arch.
InterProi IPR022909. 50S_L10_arch.
IPR001790. Ribosomal_L10/acidic_P0.
IPR001813. Ribosomal_L10/L12.
IPR013522. Ribosomal_L10_N_arc.
[Graphical view ]
Pfami PF00428. Ribosomal_60s. 1 hit.
PF00466. Ribosomal_L10. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440.
  2. "Structure of a two-domain N-terminal fragment of ribosomal protein L10 from Methanococcus jannaschii reveals a specific piece of the archaeal ribosomal stalk."
    Kravchenko O., Mitroshin I., Nikonov S., Piendl W., Garber M.
    J. Mol. Biol. 399:214-220(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.6 ANGSTROMS) OF 10-221.

Entry informationi

Entry nameiRL10_METJA
AccessioniPrimary (citable) accession number: P54049
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: July 15, 1998
Last modified: September 3, 2014
This is version 77 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Methanococcus jannaschii
    Methanococcus jannaschii: entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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