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Protein

50S ribosomal protein L12

Gene

rpl12

Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L12UniRule annotation
Gene namesi
Name:rpl12UniRule annotation
Ordered Locus Names:MJ0508
OrganismiMethanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Taxonomic identifieri243232 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanocaldococcaceaeMethanocaldococcus
Proteomesi
  • UP000000805 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001576301 – 10250S ribosomal protein L12Add BLAST102

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.UniRule annotation

Protein-protein interaction databases

STRINGi243232.MJ_0508.

Structurei

3D structure databases

ProteinModelPortaliP54048.
SMRiP54048.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eukaryotic ribosomal protein P1/P2 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04287. Archaea.
COG2058. LUCA.
InParanoidiP54048.
KOiK02869.
OMAiEYIYAAM.
OrthoDBiPOG093Z0NOH.

Family and domain databases

CDDicd05832. Ribosomal_L12p. 1 hit.
HAMAPiMF_01478. Ribosomal_L12_arch. 1 hit.
InterProiView protein in InterPro
IPR027534. Ribosomal_L12.
IPR022295. Ribosomal_L12_arc.
TIGRFAMsiTIGR03685. ribo_P1_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

P54048-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEYIYAALLL HSAGKEITED AIKAVLSAAG VEVDDARVKA LVAGLEGVDI
60 70 80 90 100
EEAIANAAMP VAAAPAAAAP AAAAEEKKEE EKKEEKKEED TAAVAGLAAL

FG
Length:102
Mass (Da):10,363
Last modified:October 1, 1996 - v1
Checksum:i35306FFDE967C52C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L77117 Genomic DNA. Translation: AAB98498.1.
PIRiD64363.
RefSeqiWP_010870009.1. NC_000909.1.

Genome annotation databases

EnsemblBacteriaiAAB98498; AAB98498; MJ_0508.
GeneIDi1451370.
KEGGimja:MJ_0508.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiRL12_METJA
AccessioniPrimary (citable) accession number: P54048
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: April 12, 2017
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Methanococcus jannaschii
    Methanococcus jannaschii: entries and gene names
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families