Reviewed, UniProtKB/Swiss-Prot P54007 (YL460_YEAST)

Names and origin

Protein names

Recommended name:
    Uncharacterized protein YLR460C

Gene names

Ordered Locus Names:	YLR460C
ORF Names:	L9122.7

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	376 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Miscellaneous	Present with 799 molecules/cell in log phase SD medium. Ref.2
Sequence similarities	Belongs to the YCR102c/YLR460c/YNL134c family.

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: InterPro
Molecular function	oxidoreductase activity Inferred from electronic annotation. Source: InterPro protein binding Inferred from physical interaction. Source: IntAct zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
SSM4	P40318	1	EBI-27168,EBI-18208

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 376	376	Uncharacterized protein YLR460C		PRO_0000203236

Sequences

	Sequence		Length	Mass (Da)
	P54007-1 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 00139949423862F1	FASTA	376	41,127
	10 20 30 40 50 60 MQVAIPETMK AVVIEDGKAV VKEGIPIPEL EEGFVLIKTL AVAGNPTDWA HIDYKIGPQG 70 80 90 100 110 120 SILGCDAAGQ IVKLGPAVNP KDFSIGDYIY GFIHGSSVRF PSNGAFAEYS AISTVVAYKS 130 140 150 160 170 180 PNELKFLGED VLPAGPVRSL EGVATIPVSL TTAGLVLTYN LGLDLKWEPS TPQRKGPILL 190 200 210 220 230 240 WGGATAVGQS LIQLANKLNG FTKIIVVASR KHEKLLKEYG ADELFDYHDI DVVEQIKHKY 250 260 270 280 290 300 NNISYLVDCV ANQDTLQQVY KCAADKQDAT IVELKNLTEE NVKKENRRQN VTIDIIRLYS 310 320 330 340 350 360 IGGHEVPFGN ITLPADSEAR KAAIKFIKFI NPKINDGQIR HIPVRVYKNG LCDVPHILKD 370 IKYGKNSGEK LVAVLN

References

[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XII." Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W., Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A., Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K., Heuss-Neitzel D., Hilbert H. , Hilger F., Kleine K., Koetter P., Louis E.J., Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S., Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D., Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M., Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P., Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M., Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K., Zollner A., Hani J., Hoheisel J.D. Nature 387:87-90(1997) [PubMed: 9169871] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U22383 Genomic DNA. Translation: AAB64723.1.
PIR	S59418.
RefSeq	NP_013565.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:4698N.
IntAct	P54007. 3 interactions.
Genome annotation databases
Ensembl	YLR460C. Saccharomyces cerevisiae. [Contig view]
GeneID	851182.
GenomeReviews	Gene locus YLR460C in contig Y13138_GR.
KEGG	sce:YLR460C.
NMPDR	fig|4932.3.peg.4596.
Organism-specific databases
CYGD	YLR460c.
SGD	S000004452. YLR460C.
Yeast-GFP	Search...
Phylogenomic databases
HOGENOM	P54007.
OMA	P54007. ANGNEAR.
Gene expression databases
ArrayExpress	P54007.
GermOnline	YLR460C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR013154. ADH_GroES-like. IPR002085. ADH_SF_Zn. IPR013149. ADH_Zn-bd. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
PANTHER	PTHR11695. ADH_Sf_Zn. 1 hit.
Pfam	PF08240. ADH_N. 1 hit. PF00107. ADH_zinc_N. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	968010.

Entry information

Entry name

YL460_YEAST

Accession

Primary (citable) accession number: P54007

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	June 16, 2009
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)