P53981 (YNB0_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized phosphatase YNL010W
EC=3.1.3.-

Gene names

Ordered Locus Names:	YNL010W
ORF Names:	N2866

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	241 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Cytoplasm. Nucleus Ref.3.
Miscellaneous	Present with 12600 molecules/cell in log phase SD medium.
Sequence similarities	Belongs to the HAD-like hydrolase superfamily.

Ontologies

Keywords
Cellular component	Cytoplasm Nucleus
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	dephosphorylation Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from direct assay Ref.3. Source: SGD nucleus Inferred from direct assay Ref.3. Source: SGD
Molecular_function	phosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 241	241	Uncharacterized phosphatase YNL010W		PRO_0000203466

Sequences

	Sequence		Length	Mass (Da)
	P53981 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 38F5D7FF14018637	FASTA	241	27,481
	10 20 30 40 50 60 MVKAVIFTDF DGTVTLEDSN DYLTDTLGFG KEKRLKVFEG VLDDTKSFRQ GFMEMLESIH 70 80 90 100 110 120 TPFPECIKIL EKKIRLDPGF KDTFEWAQEN DVPVIVVSSG MKPIIKVLLT RLVGQESIHK 130 140 150 160 170 180 IDIVSNEVEI DAHDQWKIIY KDESPFGHDK SRSIDAYKKK FESTLKAGEQ RPVYFYCGDG 190 200 210 220 230 240 VSDLSAAKEC DLLFAKRGKD LVTYCKKQNV PFHEFDTFKD ILASMKQVLA GEKTVAELME N

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications." Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J. , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J. Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[4]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z71286 Genomic DNA. Translation: CAA95870.1. BK006947 Genomic DNA. Translation: DAA10533.1.
PIR	S62922.
RefSeq	NP_014388.3. NM_001182849.3.
3D structure databases
ProteinModelPortal	P53981.
SMR	P53981. Positions 3-241.
ModBase	Search...
Protein-protein interaction databases
IntAct	P53981. 2 interactions.
STRING	4932.YNL010W.
Proteomic databases
PaxDb	P53981.
PeptideAtlas	P53981.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YNL010W; YNL010W; YNL010W.
GeneID	855722.
KEGG	sce:YNL003C. sce:YNL010W.
Organism-specific databases
CYGD	YNL010w.
SGD	S000004955. YNL010W.
Phylogenomic databases
eggNOG	COG4359.
HOGENOM	HOG000178118.
KO	K15111.
OMA	TYCEREG.
OrthoDB	EOG4NS6MP.
Gene expression databases
Genevestigator	P53981.
GermOnline	YNL010W. Saccharomyces cerevisiae.
Family and domain databases
Gene3D	3.40.50.1000. 2 hits.
InterPro	IPR023214. HAD-like_dom. IPR006383. HAD-SF_hydro_IB_PSP-like. IPR006384. PyrdxlP_Pase-rel. [Graphical view]
SUPFAM	SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR01489. DKMTPPase-SF. 1 hit. TIGR01488. HAD-SF-IB. 1 hit.
ProtoNet	Search...
Other
NextBio	980087.

Entry information

Entry name

YNB0_YEAST

Accession

Primary (citable) accession number: P53981
Secondary accession number(s): D6W1G7

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	May 1, 2013
This is version 84 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program