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P53972 (YNC2_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 91. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Methyltransferase YNL022C

EC=2.1.1.-
Gene names
Ordered Locus Names:YNL022C
ORF Names:N2815
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length490 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Miscellaneous

Present with 922 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 490490Methyltransferase YNL022C
PRO_0000203461

Regions

Region250 – 2567S-adenosyl-L-methionine binding By similarity

Sites

Active site4041Nucleophile By similarity
Binding site2801S-adenosyl-L-methionine By similarity
Binding site3081S-adenosyl-L-methionine By similarity
Binding site3271S-adenosyl-L-methionine By similarity

Sequences

Sequence LengthMass (Da)Tools
P53972 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: BB90FF7944FEA4AD

FASTA49056,177
        10         20         30         40         50         60 
MNFYRDATWV LEDIEKEAAK ERISGSMQTL VLKSCKRYKL KSNPKHIYAV LDSCWKYKPY 

        70         80         90        100        110        120 
LEKVMKKAHI LEDIPKKKGK PLFSRLTLLL LCHDLLLSKQ KRIQMGKHPI KDYVLKFKSP 

       130        140        150        160        170        180 
LHSEMVKLKL KLKVRELSEL VLSEDISNDL PPVRWIRINP LKCHPNGETE PVLAELRKKF 

       190        200        210        220        230        240 
TLKVDKWSEL VPGSIYYDEF IPNLFGIHPS DKITAHELYK HGKIIIQDRA SCFPAHILNP 

       250        260        270        280        290        300 
GPSDIVIDSC SAPGNKTTHT ASYIYPEPPK DNNTRIYAFE KDPERAKVLQ KMIKIAGCSP 

       310        320        330        340        350        360 
NISVNVGDFT KLATPEKYKD VTCFIVDPSC SGSGIFGRKF FDSFNRRKID DKDDDGGIVP 

       370        380        390        400        410        420 
DEQEEFIAKE ELQTRLAKLS SFQFQMVKHA MSFPAAKKIV YSTCSIHAEE NERVVIDLLL 

       430        440        450        460        470        480 
DKSVREWGWK VAPKREVIPS WPRRGKVEEF EEVFRDGVTY DPQQLAEGCI RALPKSDGGI 

       490 
GFFAVCFERD 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications."
Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J. expand/collapse author list , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.
Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z71298 Genomic DNA. Translation: CAA95884.1.
BK006947 Genomic DNA. Translation: DAA10523.1.
PIRS62934.
RefSeqNP_014376.3. NM_001182861.3.

3D structure databases

ProteinModelPortalP53972.
SMRP53972. Positions 154-489.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid35804. 43 interactions.
IntActP53972. 1 interaction.
MINTMINT-2491929.
STRING4932.YNL022C.

Proteomic databases

PaxDbP53972.
PeptideAtlasP53972.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYNL022C; YNL022C; YNL022C.
GeneID855709.
KEGGsce:YNL022C.

Organism-specific databases

CYGDYNL022c.
SGDS000004967. YNL022C.

Phylogenomic databases

eggNOGCOG0144.
GeneTreeENSGT00550000074709.
HOGENOMHOG000203203.
KOK15264.
OMAPGEDATN.
OrthoDBEOG74R21C.

Enzyme and pathway databases

BioCycYEAST:G3O-33060-MONOMER.

Gene expression databases

GenevestigatorP53972.

Family and domain databases

InterProIPR001678. Fmu/NOL1/Nop2p.
IPR023267. RCMT.
[Graphical view]
PfamPF01189. Nol1_Nop2_Fmu. 1 hit.
[Graphical view]
PRINTSPR02008. RCMTFAMILY.
PROSITEPS51686. SAM_MT_RSMB_NOP. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio980055.
PROP53972.

Entry information

Entry nameYNC2_YEAST
AccessionPrimary (citable) accession number: P53972
Secondary accession number(s): D6W1F7
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: April 16, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XIV

Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families