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Protein

Putative protein N-methyltransferase YNL024C

Gene

YNL024C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei51 – 511S-adenosyl-L-methionine; via amide nitrogenBy similarity
Binding sitei115 – 1151S-adenosyl-L-methionineBy similarity
Binding sitei143 – 1431S-adenosyl-L-methionine; via amide nitrogenBy similarity
Binding sitei169 – 1691S-adenosyl-L-methionine; via carbonyl oxygenBy similarity

GO - Molecular functioni

  1. S-adenosylmethionine-dependent methyltransferase activity Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciYEAST:G3O-33062-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative protein N-methyltransferase YNL024CCurated
Gene namesi
Ordered Locus Names:YNL024C
ORF Names:N2809
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome XIV

Organism-specific databases

CYGDiYNL024c.
SGDiS000004969. YNL024C.

Subcellular locationi

Cytoplasm 1 Publication

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 246246Putative protein N-methyltransferase YNL024CPRO_0000203460Add
BLAST

Proteomic databases

PaxDbiP53970.

Expressioni

Gene expression databases

GenevestigatoriP53970.

Interactioni

Protein-protein interaction databases

BioGridi35802. 20 interactions.
DIPiDIP-4380N.
IntActiP53970. 1 interaction.
MINTiMINT-487382.
STRINGi4932.YNL024C.

Structurei

3D structure databases

ProteinModelPortaliP53970.
SMRiP53970. Positions 45-246.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni87 – 893S-adenosyl-L-methionine bindingBy similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiNOG312843.
GeneTreeiENSGT00550000074572.
HOGENOMiHOG000187553.
InParanoidiP53970.
OMAiECVYFEP.
OrthoDBiEOG7DC2G8.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
InterProiIPR019410. Nicotinamide_N-MeTfrase-like.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PfamiPF10294. Methyltransf_16. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.

Sequencei

Sequence statusi: Complete.

P53970-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MESIFGGFGD LVVPRPKEHL GQTDLSFGGK LLPALKICED GGESGCGGKV
60 70 80 90 100
WIAGELLCEY ILEKSVDHLL SKTVNGTKQF KKVLELGSGT GLVGLCVGLL
110 120 130 140 150
EKNTFHDGTK VYVTDIDKLI PLLKRNIELD EVQYEVLARE LWWGEPLSAD
160 170 180 190 200
FSPQEGAMQA NNVDLVLAAD CVYLEEAFPL LEKTLLDLTH CINPPVILMA
210 220 230 240
YKKRRKADKH FFNKIKRNFD VLEITDFSKF EHYLKERTHL FQLIRK
Length:246
Mass (Da):27,738
Last modified:October 1, 1996 - v1
Checksum:iEBE1601027A37410
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z71300 Genomic DNA. Translation: CAA95886.1.
BK006947 Genomic DNA. Translation: DAA10521.1.
PIRiS62936.
RefSeqiNP_014374.1. NM_001182863.1.

Genome annotation databases

EnsemblFungiiYNL024C; YNL024C; YNL024C.
GeneIDi855707.
KEGGisce:YNL024C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z71300 Genomic DNA. Translation: CAA95886.1.
BK006947 Genomic DNA. Translation: DAA10521.1.
PIRiS62936.
RefSeqiNP_014374.1. NM_001182863.1.

3D structure databases

ProteinModelPortaliP53970.
SMRiP53970. Positions 45-246.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi35802. 20 interactions.
DIPiDIP-4380N.
IntActiP53970. 1 interaction.
MINTiMINT-487382.
STRINGi4932.YNL024C.

Proteomic databases

PaxDbiP53970.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYNL024C; YNL024C; YNL024C.
GeneIDi855707.
KEGGisce:YNL024C.

Organism-specific databases

CYGDiYNL024c.
SGDiS000004969. YNL024C.

Phylogenomic databases

eggNOGiNOG312843.
GeneTreeiENSGT00550000074572.
HOGENOMiHOG000187553.
InParanoidiP53970.
OMAiECVYFEP.
OrthoDBiEOG7DC2G8.

Enzyme and pathway databases

BioCyciYEAST:G3O-33062-MONOMER.

Miscellaneous databases

NextBioi980049.
PROiP53970.

Gene expression databases

GenevestigatoriP53970.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
InterProiIPR019410. Nicotinamide_N-MeTfrase-like.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PfamiPF10294. Methyltransf_16. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications."
    Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J.
    , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.
    Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  4. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiYNC4_YEAST
AccessioniPrimary (citable) accession number: P53970
Secondary accession number(s): D6W1F5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: February 4, 2015
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 1760 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XIV
    Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.