Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Actin-related protein 5

Gene

ARP5

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex.

Miscellaneous

Present with 2170 molecules/cell in log phase SD medium.1 Publication

GO - Biological processi

  • chromatin remodeling Source: SGD
  • DNA duplex unwinding Source: GOC
  • nucleosome mobilization Source: SGD
  • regulation of transcription, DNA-templated Source: UniProtKB-KW
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciYEAST:G3O-33090-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Actin-related protein 5
Alternative name(s):
Actin-like protein ARP5
Gene namesi
Name:ARP5
Ordered Locus Names:YNL059C
ORF Names:N2430, YNL2430C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIV

Organism-specific databases

EuPathDBiFungiDB:YNL059C
SGDiS000005004 ARP5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000891041 – 755Actin-related protein 5Add BLAST755

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei7PhosphoserineCombined sources1
Cross-linki12Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)Combined sources
Modified residuei24PhosphothreonineCombined sources1
Modified residuei383PhosphoserineCombined sources1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

MaxQBiP53946
PaxDbiP53946
PRIDEiP53946

PTM databases

iPTMnetiP53946

Interactioni

Subunit structurei

Component of the chromatin-remodeling INO80 complex, at least composed of ARP4, ARP5, ARP8, RVB1, RVB2, TAF14, NHP10, IES1, IES3, IES4, IES6, ACT1, IES2, IES5 and INO80.1 Publication

Protein-protein interaction databases

BioGridi35763, 48 interactors
IntActiP53946, 26 interactors
MINTiP53946
STRINGi4932.YNL059C

Structurei

3D structure databases

ProteinModelPortaliP53946
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the actin family.Curated

Phylogenomic databases

GeneTreeiENSGT00720000108866
HOGENOMiHOG000171615
InParanoidiP53946
KOiK11672
OMAiNVGGYHI
OrthoDBiEOG092C0R1R

Family and domain databases

InterProiView protein in InterPro
IPR004000 Actin
IPR027664 Arp5
PANTHERiPTHR11937 PTHR11937, 1 hit
PTHR11937:SF16 PTHR11937:SF16, 1 hit
PfamiView protein in Pfam
PF00022 Actin, 2 hits
SMARTiView protein in SMART
SM00268 ACTIN, 1 hit

Sequencei

Sequence statusi: Complete.

P53946-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSRDASLTP LKAVVIDDPP LRQTPEPFDE QSAYNPQSPI AIDFGSSKLR
60 70 80 90 100
AGFVNHATPT HIFPNALTKF RDRKLNKNFT FVGNDTLLDQ AVRSQSRSPF
110 120 130 140 150
DGPFVTNWNL TEEILDYTFH HLGVVPDNGI PNPILLTERL ATVQSQRTNW
160 170 180 190 200
YQILFETYNV PGVTFGIDSL FSFYNYNPSG NKTGLVISCG HEDTNVIPVV
210 220 230 240 250
DGAGILTDAK RINWGGHQAV DYLNDLMALK YPYFPTKMSY LQYETMYKDY
260 270 280 290 300
CYVSRNYDED IEKILTLENL DTNDVVVEAP FTEVLQPQKT EEELRIQAEK
310 320 330 340 350
RKETGKRLQE QARLKRMEKL VQKQEEFEYF SKVRDQLIDE PKKKVLSVLQ
360 370 380 390 400
NAGFDDERDF KKYLHSLEQS LKKAQMVEAE DDSHLDEMNE DKTAQKFDLL
410 420 430 440 450
DIADEDLNED QIKEKRKQRF LKASQDARQK AKEEKERVAK EEEEKKLKEQ
460 470 480 490 500
QWRETDLNGW IKDKRLKLNK LIKRRKEKLK LRDEMKDRKS QVSQNRMKNL
510 520 530 540 550
ASLAEDNVKQ GAKRNRHQAT IDNDPNDTFG ANDEDWLIYT DITQNPEAFE
560 570 580 590 600
EALEYEYKDI VELERLLLEH DPNFTEEDTL EAQYDWRNSI LHLFLRGPRP
610 620 630 640 650
HDSENIHEQH QMHLNVERIR VPEVIFQPTM GGQDQAGICE LSETILLKKF
660 670 680 690 700
GSQPGKLSQT SIDMVNNVLI TGGNAKVPGL KERIVKEFTG FLPTGTNITV
710 720 730 740 750
NMSSDPSLDA WKGMAALARN EEQYRKTVIS KKEYEEYGPE YIKEHKLGNT

KYFED
Length:755
Mass (Da):87,560
Last modified:October 1, 1996 - v1
Checksum:iD8748B9096B32B53
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U12141 Genomic DNA Translation: AAA99652.1
Z71335 Genomic DNA Translation: CAA95933.1
BK006947 Genomic DNA Translation: DAA10486.1
PIRiS58718
RefSeqiNP_014339.1, NM_001182898.1

Genome annotation databases

EnsemblFungiiYNL059C; YNL059C; YNL059C
GeneIDi855665
KEGGisce:YNL059C

Similar proteinsi

Entry informationi

Entry nameiARP5_YEAST
AccessioniPrimary (citable) accession number: P53946
Secondary accession number(s): D6W1C0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 23, 2018
This is version 150 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XIV
    Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health