Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

N-glycosylation protein EOS1

Gene

EOS1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Involved in oxidative stress resistance and N-glycosylation.1 Publication

GO - Biological processi

  • cellular response to oxidative stress Source: SGD
  • protein N-linked glycosylation Source: SGD
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-33109-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
N-glycosylation protein EOS1
Alternative name(s):
ER-localized and oxidants sensitive protein 1
Gene namesi
Name:EOS1
Ordered Locus Names:YNL080C
ORF Names:N2327
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIV

Organism-specific databases

EuPathDBiFungiDB:YNL080C.
SGDiS000005024. EOS1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 136LumenalSequence analysisAdd BLAST136
Transmembranei137 – 157HelicalSequence analysisAdd BLAST21
Topological domaini158 – 167CytoplasmicSequence analysis10
Transmembranei168 – 188HelicalSequence analysisAdd BLAST21
Topological domaini189 – 195LumenalSequence analysis7
Transmembranei196 – 216HelicalSequence analysisAdd BLAST21
Topological domaini217 – 321CytoplasmicSequence analysisAdd BLAST105
Transmembranei322 – 342HelicalSequence analysisAdd BLAST21
Topological domaini343 – 366LumenalSequence analysisAdd BLAST24

GO - Cellular componenti

  • endoplasmic reticulum membrane Source: SGD
  • integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002034461 – 366N-glycosylation protein EOS1Add BLAST366

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi103N-linked (GlcNAc...)Sequence analysis1
Glycosylationi104N-linked (GlcNAc...)Sequence analysis1

Post-translational modificationi

N-glycosylated.1 Publication

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiP53938.
PRIDEiP53938.

PTM databases

iPTMnetiP53938.

Interactioni

Protein-protein interaction databases

BioGridi35743. 186 interactors.
IntActiP53938. 1 interactor.

Structurei

3D structure databases

ProteinModelPortaliP53938.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the EOS1 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000248035.
InParanoidiP53938.
OMAiHTWILIS.
OrthoDBiEOG092C584B.

Family and domain databases

InterProiIPR021100. N-glycosylation_EOS1.
[Graphical view]
PfamiPF12326. EOS1. 1 hit.
[Graphical view]
PRINTSiPR02070. NGLYCOSEOS1.

Sequencei

Sequence statusi: Complete.

P53938-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTWILSTGMG PHEDKYAKHE RATFKKTYSS MKTLSLNHLT AKQHMLMALC
60 70 80 90 100
RDISLLPPLT YIFTSLRKAW RVSMRTSITL YEPQSLRDAF TYFWQKLNSA
110 120 130 140 150
YDNNSSFEGA SQKAVNGDGK DSLLLSALTT ARASEYLLCS LWCLVSLYLS
160 170 180 190 200
YAILDSLMVR WIVKYSTVAA ILRMFSMSLI IVTLELLLLS SLSPELDYFL
210 220 230 240 250
HTWILISCVL TAVYIWQSYL TSDLRYIRNQ EGEVQEDTNV PEETEDYEDG
260 270 280 290 300
EDDADEDSHV VVADESTVDV PSNDSLSDNS DGGLFPVNRP SVSHSQSPKR
310 320 330 340 350
PKKYPKKAFN FTTKRTIDLY KITVLCVVPV GLASFITMLG LLRNLFIQRL
360
DVEQLERILH EMHPPA
Length:366
Mass (Da):41,674
Last modified:October 1, 1996 - v1
Checksum:iCFE1BA51A638DF5A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ115393 Genomic DNA. Translation: AAZ22528.1.
X86470 Genomic DNA. Translation: CAA60178.1.
Z71356 Genomic DNA. Translation: CAA95954.1.
BK006947 Genomic DNA. Translation: DAA10465.1.
PIRiS53898.
RefSeqiNP_014319.1. NM_001182918.1.

Genome annotation databases

EnsemblFungiiYNL080C; YNL080C; YNL080C.
GeneIDi855644.
KEGGisce:YNL080C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ115393 Genomic DNA. Translation: AAZ22528.1.
X86470 Genomic DNA. Translation: CAA60178.1.
Z71356 Genomic DNA. Translation: CAA95954.1.
BK006947 Genomic DNA. Translation: DAA10465.1.
PIRiS53898.
RefSeqiNP_014319.1. NM_001182918.1.

3D structure databases

ProteinModelPortaliP53938.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi35743. 186 interactors.
IntActiP53938. 1 interactor.

PTM databases

iPTMnetiP53938.

Proteomic databases

MaxQBiP53938.
PRIDEiP53938.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYNL080C; YNL080C; YNL080C.
GeneIDi855644.
KEGGisce:YNL080C.

Organism-specific databases

EuPathDBiFungiDB:YNL080C.
SGDiS000005024. EOS1.

Phylogenomic databases

HOGENOMiHOG000248035.
InParanoidiP53938.
OMAiHTWILIS.
OrthoDBiEOG092C584B.

Enzyme and pathway databases

BioCyciYEAST:G3O-33109-MONOMER.

Miscellaneous databases

PROiP53938.

Family and domain databases

InterProiIPR021100. N-glycosylation_EOS1.
[Graphical view]
PfamiPF12326. EOS1. 1 hit.
[Graphical view]
PRINTSiPR02070. NGLYCOSEOS1.
ProtoNetiSearch...

Entry informationi

Entry nameiEOS1_YEAST
AccessioniPrimary (citable) accession number: P53938
Secondary accession number(s): D6W199, Q45TY2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: November 2, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 937 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XIV
    Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.