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P53934

- YNJ2_YEAST

UniProt

P53934 - YNJ2_YEAST

Protein

UPF0586 protein YNL092W

Gene

YNL092W

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 99 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. S-adenosylmethionine-dependent methyltransferase activity Source: SGD

    GO - Biological processi

    1. methylation Source: GOC

    Enzyme and pathway databases

    BioCyciYEAST:G3O-33120-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    UPF0586 protein YNL092W
    Gene namesi
    Ordered Locus Names:YNL092W
    ORF Names:N2227
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome XIV

    Organism-specific databases

    CYGDiYNL092w.
    SGDiS000005036. YNL092W.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 400400UPF0586 protein YNL092WPRO_0000203441Add
    BLAST

    Proteomic databases

    PaxDbiP53934.
    PRIDEiP53934.

    Expressioni

    Gene expression databases

    GenevestigatoriP53934.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    itself1EBI-28794,EBI-28794
    BZZ1P388221EBI-28794,EBI-3889
    FIP1P459761EBI-28794,EBI-6940
    JJJ3P471381EBI-28794,EBI-25576
    KGD2P192621EBI-28794,EBI-12464
    SCD5P347581EBI-28794,EBI-16685
    YAP6Q039351EBI-28794,EBI-37603
    YML037CQ037031EBI-28794,EBI-27772

    Protein-protein interaction databases

    BioGridi35732. 19 interactions.
    DIPiDIP-1880N.
    IntActiP53934. 10 interactions.
    MINTiMINT-391242.
    STRINGi4932.YNL092W.

    Structurei

    3D structure databases

    ProteinModelPortaliP53934.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the UPF0586 family.Curated

    Phylogenomic databases

    eggNOGiNOG323736.
    GeneTreeiENSGT00390000005323.
    HOGENOMiHOG000204444.
    OMAiVVANATH.
    OrthoDBiEOG7ZKSMD.

    Family and domain databases

    Gene3Di3.40.50.150. 2 hits.
    InterProiIPR012901. N2227.
    IPR029063. SAM-dependent_MTases-like.
    [Graphical view]
    PfamiPF07942. N2227. 1 hit.
    [Graphical view]
    SUPFAMiSSF53335. SSF53335. 2 hits.

    Sequencei

    Sequence statusi: Complete.

    P53934-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDENEFDNQR ENKAVARVII SFLKYEEYAL KEIYNLRVKK WASISDRQKD    50
    MVPNYTKYLA NLKAAIIENG KFFRSVAEYA LQSISFEPGE IVQPNDLDMS 100
    KTCSLLTQVY REWSAEAISE RNCLNSRLVP FLKTLSPPKA DILIPGCGTG 150
    RLLVDLSRMG YNCEGNEFSY HMLLVSQYML NAGLLQNQII IYPFIHCFSH 200
    WKKIEDQLSP IKVPDIEAWS SNKGMGSMSI CAGSFVDCYG RNQGTKISSH 250
    YTFSRRMQLS RAKAENSKDV VVTNFFIDTG SNILDYLDTI GHVLKPGGIW 300
    CNFGPLLYHF ENDHGVETTY EVNPYSGFQD KINDYTPLMG LELSSDDIIS 350
    IATNHLDFEL IRRESGILCG YGRYAGPESC AMPGYMCHYW ILKSNPTNES 400
    Length:400
    Mass (Da):45,497
    Last modified:October 1, 1996 - v1
    Checksum:i6B6C051891F075EE
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti42 – 421A → E in strain: SK1.
    Natural varianti154 – 1541V → M in strain: SK1.
    Natural varianti317 – 3171E → D in strain: SK1.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X85811 Genomic DNA. Translation: CAA59825.1.
    DQ115393 Genomic DNA. Translation: AAZ22516.1.
    Z71368 Genomic DNA. Translation: CAA95968.1.
    BK006947 Genomic DNA. Translation: DAA10454.1.
    PIRiS52733.
    RefSeqiNP_014307.1. NM_001182930.1.

    Genome annotation databases

    EnsemblFungiiYNL092W; YNL092W; YNL092W.
    GeneIDi855632.
    KEGGisce:YNL092W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X85811 Genomic DNA. Translation: CAA59825.1 .
    DQ115393 Genomic DNA. Translation: AAZ22516.1 .
    Z71368 Genomic DNA. Translation: CAA95968.1 .
    BK006947 Genomic DNA. Translation: DAA10454.1 .
    PIRi S52733.
    RefSeqi NP_014307.1. NM_001182930.1.

    3D structure databases

    ProteinModelPortali P53934.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 35732. 19 interactions.
    DIPi DIP-1880N.
    IntActi P53934. 10 interactions.
    MINTi MINT-391242.
    STRINGi 4932.YNL092W.

    Proteomic databases

    PaxDbi P53934.
    PRIDEi P53934.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YNL092W ; YNL092W ; YNL092W .
    GeneIDi 855632.
    KEGGi sce:YNL092W.

    Organism-specific databases

    CYGDi YNL092w.
    SGDi S000005036. YNL092W.

    Phylogenomic databases

    eggNOGi NOG323736.
    GeneTreei ENSGT00390000005323.
    HOGENOMi HOG000204444.
    OMAi VVANATH.
    OrthoDBi EOG7ZKSMD.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-33120-MONOMER.

    Miscellaneous databases

    NextBioi 979845.

    Gene expression databases

    Genevestigatori P53934.

    Family and domain databases

    Gene3Di 3.40.50.150. 2 hits.
    InterProi IPR012901. N2227.
    IPR029063. SAM-dependent_MTases-like.
    [Graphical view ]
    Pfami PF07942. N2227. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53335. SSF53335. 2 hits.
    ProtoNeti Search...

    Publicationsi

    1. "Sequence analysis of a 14.2 kb fragment of Saccharomyces cerevisiae chromosome XIV that includes the ypt53, tRNALeu and gsr m2 genes and four new open reading frames."
      Garcia-Cantalejo J.M., Boskovic J., Jimenez A.
      Yeast 12:599-608(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 96604 / S288c / FY1679.
    2. "Quantitative trait loci mapped to single-nucleotide resolution in yeast."
      Deutschbauer A.M., Davis R.W.
      Nat. Genet. 37:1333-1340(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: SK1.
    3. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications."
      Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J.
      , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.
      Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
    6. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiYNJ2_YEAST
    AccessioniPrimary (citable) accession number: P53934
    Secondary accession number(s): D6W188, Q45TZ4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 99 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 952 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Uncharacterized protein families (UPF)
      List of uncharacterized protein family (UPF) entries
    3. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    4. Yeast chromosome XIV
      Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

    External Data

    Dasty 3