P53934 (YNJ2_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
UPF0586 protein YNL092W

Gene names

Ordered Locus Names:	YNL092W
ORF Names:	N2227

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	400 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Miscellaneous	Present with 952 molecules/cell in log phase SD medium.
Sequence similarities	Belongs to the UPF0586 family.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	S-adenosylmethionine-dependent methyltransferase activity Inferred from sequence or structural similarity PubMed 12872006. Source: SGD
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
itself		1	EBI-28794,EBI-28794
BZZ1	P38822	1	EBI-28794,EBI-3889
FIP1	P45976	1	EBI-28794,EBI-6940
JJJ3	P47138	1	EBI-28794,EBI-25576
KGD2	P19262	1	EBI-28794,EBI-12464
SCD5	P34758	1	EBI-28794,EBI-16685
YAP6	Q03935	1	EBI-28794,EBI-37603
YML037C	Q03703	1	EBI-28794,EBI-27772

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 400	400	UPF0586 protein YNL092W		PRO_0000203441
Natural variations
	Natural variant	42	1	A → E in strain: SK1.
	Natural variant	154	1	V → M in strain: SK1.
	Natural variant	317	1	E → D in strain: SK1.

Sequences

	Sequence		Length	Mass (Da)
	P53934 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 6B6C051891F075EE	FASTA	400	45,497
	10 20 30 40 50 60 MDENEFDNQR ENKAVARVII SFLKYEEYAL KEIYNLRVKK WASISDRQKD MVPNYTKYLA 70 80 90 100 110 120 NLKAAIIENG KFFRSVAEYA LQSISFEPGE IVQPNDLDMS KTCSLLTQVY REWSAEAISE 130 140 150 160 170 180 RNCLNSRLVP FLKTLSPPKA DILIPGCGTG RLLVDLSRMG YNCEGNEFSY HMLLVSQYML 190 200 210 220 230 240 NAGLLQNQII IYPFIHCFSH WKKIEDQLSP IKVPDIEAWS SNKGMGSMSI CAGSFVDCYG 250 260 270 280 290 300 RNQGTKISSH YTFSRRMQLS RAKAENSKDV VVTNFFIDTG SNILDYLDTI GHVLKPGGIW 310 320 330 340 350 360 CNFGPLLYHF ENDHGVETTY EVNPYSGFQD KINDYTPLMG LELSSDDIIS IATNHLDFEL 370 380 390 400 IRRESGILCG YGRYAGPESC AMPGYMCHYW ILKSNPTNES

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence analysis of a 14.2 kb fragment of Saccharomyces cerevisiae chromosome XIV that includes the ypt53, tRNALeu and gsr m2 genes and four new open reading frames." Garcia-Cantalejo J.M., Boskovic J., Jimenez A. Yeast 12:599-608(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[2]	"Quantitative trait loci mapped to single-nucleotide resolution in yeast." Deutschbauer A.M., Davis R.W. Nat. Genet. 37:1333-1340(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: SK1.
[3]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications." Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J. , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J. Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[4]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[5]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X85811 Genomic DNA. Translation: CAA59825.1. DQ115393 Genomic DNA. Translation: AAZ22516.1. Z71368 Genomic DNA. Translation: CAA95968.1. BK006947 Genomic DNA. Translation: DAA10454.1.
PIR	S52733.
RefSeq	NP_014307.1. NM_001182930.1.
3D structure databases
ProteinModelPortal	P53934.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-1880N.
IntAct	P53934. 10 interactions.
MINT	MINT-391242.
STRING	4932.YNL092W.
Proteomic databases
PaxDb	P53934.
PRIDE	P53934.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YNL092W; YNL092W; YNL092W.
GeneID	855632.
KEGG	sce:YNL092W.
Organism-specific databases
CYGD	YNL092w.
SGD	S000005036. YNL092W.
Phylogenomic databases
eggNOG	NOG323736.
GeneTree	ENSGT00390000005323.
HOGENOM	HOG000204444.
OMA	REATFKP.
OrthoDB	EOG4HHS9Z.
Gene expression databases
Genevestigator	P53934.
GermOnline	YNL092W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR012901. N2227. [Graphical view]
Pfam	PF07942. N2227. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	979845.

Entry information

Entry name

YNJ2_YEAST

Accession

Primary (citable) accession number: P53934
Secondary accession number(s): D6W188, Q45TZ4

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	May 1, 2013
This is version 86 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program