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Protein

54S ribosomal protein bL35m

Gene

YNL122C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.2 Publications

GO - Molecular functioni

  • structural constituent of ribosome Source: SGD

GO - Biological processi

  • mitochondrial translation Source: SGD

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-33143-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
54S ribosomal protein bL35m1 Publication
Alternative name(s):
Mitochondrial large ribosomal subunit protein bL35m1 Publication
Gene namesi
Ordered Locus Names:YNL122C
ORF Names:N1901
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIV

Organism-specific databases

EuPathDBiFungiDB:YNL122C
SGDiS000005066 YNL122C

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000203430? – 11554S ribosomal protein bL35m
Transit peptidei1 – ?MitochondrionSequence analysis

Proteomic databases

PaxDbiP53921
PRIDEiP53921

Interactioni

Subunit structurei

Component of the mitochondrial large ribosomal subunit (mt-LSU). Mature yeast 74S mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S small subunit contains a 15S ribosomal RNA (15S mt-rRNA) and 34 different proteins. The 54S large subunit contains a 21S rRNA (21S mt-rRNA) and 46 different proteins.1 Publication

Protein-protein interaction databases

BioGridi35705, 88 interactors
DIPiDIP-2009N
IntActiP53921, 2 interactors
MINTiP53921
STRINGi4932.YNL122C

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3J6Belectron microscopy3.20Z1-115[»]
5MRCelectron microscopy3.25Z54-115[»]
5MREelectron microscopy3.75Z54-115[»]
5MRFelectron microscopy4.97Z54-115[»]
ProteinModelPortaliP53921
SMRiP53921
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

HOGENOMiHOG000248549
InParanoidiP53921
OrthoDBiEOG092C5Q5V

Family and domain databases

InterProiView protein in InterPro
IPR021137 Ribosomal_L35
IPR037229 Ribosomal_L35_sf
PANTHERiPTHR33343 PTHR33343, 1 hit
PfamiView protein in Pfam
PF01632 Ribosomal_L35p, 1 hit
SUPFAMiSSF143034 SSF143034, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P53921-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKISLHNKRQ RGDQNQNMSV FNVLKPLLKG SNSFKVKLNG FLFNNVSTIT
60 70 80 90 100
IRTLMKTHKG TAKRWRRTGN TFKRGIAGRK HGNIGWSHRS LKALTGRKIA
110
HPAYSKHLKR LLPYH
Length:115
Mass (Da):13,244
Last modified:October 1, 1996 - v1
Checksum:iB6C9DC84CE1EB016
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti11R → Q in strain: V1-09 and YJM339. 1 Publication1
Natural varianti31S → P in strain: YJM269, YJM270, YJM326 and YJM1129. 1 Publication1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF125216 Genomic DNA Translation: ABN58536.1
EF125217 Genomic DNA Translation: ABN58545.1
EF125218 Genomic DNA Translation: ABN58554.1
EF125219 Genomic DNA Translation: ABN58563.1
EF125220 Genomic DNA Translation: ABN58572.1
EF125221 Genomic DNA Translation: ABN58581.1
EF125222 Genomic DNA Translation: ABN58590.1
EF125223 Genomic DNA Translation: ABN58599.1
EF125224 Genomic DNA Translation: ABN58608.1
EF125225 Genomic DNA Translation: ABN58617.1
EF125226 Genomic DNA Translation: ABN58626.1
EF125228 Genomic DNA Translation: ABN58644.1
Z69382 Genomic DNA Translation: CAA93385.1
Z71398 Genomic DNA Translation: CAA96003.1
AY692589 Genomic DNA Translation: AAT92608.1
BK006947 Genomic DNA Translation: DAA10427.1
PIRiS63063
RefSeqiNP_014277.1, NM_001182960.1

Genome annotation databases

EnsemblFungiiYNL122C; YNL122C; YNL122C
GeneIDi855601
KEGGisce:YNL122C

Similar proteinsi

Entry informationi

Entry nameiYNM2_YEAST
AccessioniPrimary (citable) accession number: P53921
Secondary accession number(s): B0KZR4
, B0KZU1, B0KZY6, D6W161
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 23, 2018
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

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