P53921 (YNM2_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative mitochondrial ribosomal protein YNL122C

Gene names

Ordered Locus Names:	YNL122C
ORF Names:	N1901

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	115 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Mitochondrion Ref.6 Ref.7.
Sequence similarities	Belongs to the ribosomal protein L35P family.

Ontologies

Keywords
Cellular component	Mitochondrion
Domain	Transit peptide
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	translation Inferred from electronic annotation. Source: InterPro
Cellular_component	mitochondrion Inferred from direct assay Ref.6Ref.7. Source: SGD ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – ?		Mitochondrion Potential
	Chain	? – 115		Putative mitochondrial ribosomal protein YNL122C		PRO_0000203430
Natural variations
	Natural variant	11	1	R → Q in strain: V1-09 and YJM339. Ref.1
	Natural variant	31	1	S → P in strain: YJM269, YJM270, YJM326 and YJM1129. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P53921 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: B6C9DC84CE1EB016	FASTA	115	13,244
	10 20 30 40 50 60 MKISLHNKRQ RGDQNQNMSV FNVLKPLLKG SNSFKVKLNG FLFNNVSTIT IRTLMKTHKG 70 80 90 100 110 TAKRWRRTGN TFKRGIAGRK HGNIGWSHRS LKALTGRKIA HPAYSKHLKR LLPYH

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequential elimination of major-effect contributors identifies additional quantitative trait loci conditioning high-temperature growth in yeast." Sinha H., David L., Pascon R.C., Clauder-Muenster S., Krishnakumar S., Nguyen M., Shi G., Dean J., Davis R.W., Oefner P.J., McCusker J.H., Steinmetz L.M. Genetics 180:1661-1670(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANTS GLN-11 AND PRO-31. Strain: ATCC 200060 / W303, S103, SK1, V1-09, YJM 1129, YJM 269, YJM 270, YJM 320, YJM 326, YJM 339, YJM 627 and YJM230.
[2]	"The DNA sequence of cosmid 14-13b from chromosome XIV of Saccharomyces cerevisiae reveals an unusually high number of overlapping open reading frames." de Antoni A., D'Angelo M., Dal Pero F., Sartorello F., Pandolfo D., Pallavicini A., Lanfranchi G., Valle G. Yeast 13:261-266(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications." Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J. , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J. Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[4]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[5]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[6]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[7]	"Assessing systems properties of yeast mitochondria through an interaction map of the organelle." Perocchi F., Jensen L.J., Gagneur J., Ahting U., von Mering C., Bork P., Prokisch H., Steinmetz L.M. PLoS Genet. 2:E170-E170(2006) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	EF125216 Genomic DNA. Translation: ABN58536.1. EF125217 Genomic DNA. Translation: ABN58545.1. EF125218 Genomic DNA. Translation: ABN58554.1. EF125219 Genomic DNA. Translation: ABN58563.1. EF125220 Genomic DNA. Translation: ABN58572.1. EF125221 Genomic DNA. Translation: ABN58581.1. EF125222 Genomic DNA. Translation: ABN58590.1. EF125223 Genomic DNA. Translation: ABN58599.1. EF125224 Genomic DNA. Translation: ABN58608.1. EF125225 Genomic DNA. Translation: ABN58617.1. EF125226 Genomic DNA. Translation: ABN58626.1. EF125228 Genomic DNA. Translation: ABN58644.1. Z69382 Genomic DNA. Translation: CAA93385.1. Z71398 Genomic DNA. Translation: CAA96003.1. AY692589 Genomic DNA. Translation: AAT92608.1. BK006947 Genomic DNA. Translation: DAA10427.1.
PIR	S63063.
RefSeq	NP_014277.1. NM_001182960.1.
3D structure databases
ProteinModelPortal	P53921.
SMR	P53921. Positions 54-114.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-2009N.
IntAct	P53921. 1 interaction.
MINT	MINT-396727.
STRING	4932.YNL122C.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YNL122C; YNL122C; YNL122C.
GeneID	855601.
KEGG	sce:YNL122C.
Organism-specific databases
CYGD	YNL122c.
SGD	S000005066. YNL122C.
Phylogenomic databases
eggNOG	COG0291.
HOGENOM	HOG000248549.
OrthoDB	EOG4ZKNX4.
Gene expression databases
Genevestigator	P53921.
GermOnline	YNL122C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR021137. Ribosomal_L35. [Graphical view]
Pfam	PF01632. Ribosomal_L35p. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	979765.

Entry information

Entry name

YNM2_YEAST

Accession

Primary (citable) accession number: P53921
Secondary accession number(s): B0KZR4 , B0KZU1, B0KZY6, D6W161

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	April 3, 2013
This is version 84 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program