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P53921 (YNM2_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 90. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (5) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative mitochondrial ribosomal protein YNL122C
Gene names
Ordered Locus Names:YNL122C
ORF Names:N1901
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length115 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Mitochondrion Ref.6 Ref.7.

Sequence similarities

Belongs to the ribosomal protein L35P family.

Ontologies

Keywords
   Cellular componentMitochondrion
   DomainTransit peptide
   Molecular functionRibonucleoprotein
Ribosomal protein
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtranslation

Inferred from electronic annotation. Source: InterPro

   Cellular_componentmitochondrion

Inferred from direct assay Ref.7. Source: SGD

ribosome

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionstructural constituent of ribosome

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – ?Mitochondrion Potential
Chain? – 115Putative mitochondrial ribosomal protein YNL122CPRO_0000203430

Natural variations

Natural variant111R → Q in strain: V1-09 and YJM339. Ref.1
Natural variant311S → P in strain: YJM269, YJM270, YJM326 and YJM1129. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P53921 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: B6C9DC84CE1EB016

FASTA11513,244
        10         20         30         40         50         60 
MKISLHNKRQ RGDQNQNMSV FNVLKPLLKG SNSFKVKLNG FLFNNVSTIT IRTLMKTHKG 

        70         80         90        100        110 
TAKRWRRTGN TFKRGIAGRK HGNIGWSHRS LKALTGRKIA HPAYSKHLKR LLPYH 

« Hide

References

« Hide 'large scale' references
[1]"Sequential elimination of major-effect contributors identifies additional quantitative trait loci conditioning high-temperature growth in yeast."
Sinha H., David L., Pascon R.C., Clauder-Muenster S., Krishnakumar S., Nguyen M., Shi G., Dean J., Davis R.W., Oefner P.J., McCusker J.H., Steinmetz L.M.
Genetics 180:1661-1670(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANTS GLN-11 AND PRO-31.
Strain: ATCC 200060 / W303, S103, SK1, V1-09, YJM 1129, YJM 269, YJM 270, YJM 320, YJM 326, YJM 339, YJM 627 and YJM230.
[2]"The DNA sequence of cosmid 14-13b from chromosome XIV of Saccharomyces cerevisiae reveals an unusually high number of overlapping open reading frames."
de Antoni A., D'Angelo M., Dal Pero F., Sartorello F., Pandolfo D., Pallavicini A., Lanfranchi G., Valle G.
Yeast 13:261-266(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications."
Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J. expand/collapse author list , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.
Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[4]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[5]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[6]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[7]"Assessing systems properties of yeast mitochondria through an interaction map of the organelle."
Perocchi F., Jensen L.J., Gagneur J., Ahting U., von Mering C., Bork P., Prokisch H., Steinmetz L.M.
PLoS Genet. 2:E170-E170(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
EF125216 Genomic DNA. Translation: ABN58536.1.
EF125217 Genomic DNA. Translation: ABN58545.1.
EF125218 Genomic DNA. Translation: ABN58554.1.
EF125219 Genomic DNA. Translation: ABN58563.1.
EF125220 Genomic DNA. Translation: ABN58572.1.
EF125221 Genomic DNA. Translation: ABN58581.1.
EF125222 Genomic DNA. Translation: ABN58590.1.
EF125223 Genomic DNA. Translation: ABN58599.1.
EF125224 Genomic DNA. Translation: ABN58608.1.
EF125225 Genomic DNA. Translation: ABN58617.1.
EF125226 Genomic DNA. Translation: ABN58626.1.
EF125228 Genomic DNA. Translation: ABN58644.1.
Z69382 Genomic DNA. Translation: CAA93385.1.
Z71398 Genomic DNA. Translation: CAA96003.1.
AY692589 Genomic DNA. Translation: AAT92608.1.
BK006947 Genomic DNA. Translation: DAA10427.1.
PIRS63063.
RefSeqNP_014277.1. NM_001182960.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1VW4electron microscopy3.20Z1-115[»]
ProteinModelPortalP53921.
SMRP53921. Positions 56-111.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid35705. 42 interactions.
DIPDIP-2009N.
IntActP53921. 1 interaction.
MINTMINT-396727.
STRING4932.YNL122C.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYNL122C; YNL122C; YNL122C.
GeneID855601.
KEGGsce:YNL122C.

Organism-specific databases

CYGDYNL122c.
SGDS000005066. YNL122C.

Phylogenomic databases

eggNOGCOG0291.
HOGENOMHOG000248549.
OMAADSTHMH.
OrthoDBEOG73Z36X.

Enzyme and pathway databases

BioCycYEAST:G3O-33143-MONOMER.

Gene expression databases

GenevestigatorP53921.

Family and domain databases

InterProIPR021137. Ribosomal_L35.
[Graphical view]
PfamPF01632. Ribosomal_L35p. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio979765.

Entry information

Entry nameYNM2_YEAST
AccessionPrimary (citable) accession number: P53921
Secondary accession number(s): B0KZR4 expand/collapse secondary AC list , B0KZU1, B0KZY6, D6W161
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: June 11, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XIV

Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references