UniProtKB - P53917 (FAR11_YEAST)
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Protein
Factor arrest protein 11
Gene
FAR11
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Participates in the control of the reentry into the cell cycle following pheromone treatment.2 Publications
Miscellaneous
Present with 1080 molecules/cell in log phase SD medium.1 Publication
GO - Biological processi
- intra-S DNA damage checkpoint Source: SGD
- positive regulation of macroautophagy Source: SGD
- re-entry into mitotic cell cycle after pheromone arrest Source: SGD
Keywordsi
Biological process | Cell cycle |
Enzyme and pathway databases
BioCyci | YEAST:G3O-33148-MONOMER. |
Names & Taxonomyi
Protein namesi | Recommended name: Factor arrest protein 11 |
Gene namesi | Name:FAR11 Ordered Locus Names:YNL127W ORF Names:N1221, N1875 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
EuPathDBi | FungiDB:YNL127W. |
SGDi | S000005071. FAR11. |
Subcellular locationi
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000087190 | 1 – 953 | Factor arrest protein 11Add BLAST | 953 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 18 | PhosphoserineCombined sources | 1 | |
Modified residuei | 81 | PhosphoserineCombined sources | 1 | |
Modified residuei | 524 | PhosphoserineCombined sources | 1 | |
Modified residuei | 527 | PhosphoserineCombined sources | 1 | |
Modified residuei | 528 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
MaxQBi | P53917. |
PaxDbi | P53917. |
PRIDEi | P53917. |
PTM databases
iPTMneti | P53917. |
Interactioni
Subunit structurei
Component of a complex at least composed of FAR3, FAR7, FAR8, FAR10, FAR11 and VPS64.
Binary interactionsi
With | Entry | #Exp. | IntAct | Notes |
---|---|---|---|---|
FAR3 | P46671 | 2 | EBI-28900,EBI-6789 |
Protein-protein interaction databases
BioGridi | 35700. 256 interactors. |
DIPi | DIP-1830N. |
IntActi | P53917. 25 interactors. |
MINTi | P53917. |
STRINGi | 4932.YNL127W. |
Family & Domainsi
Sequence similaritiesi
Belongs to the FAR11 family.Curated
Phylogenomic databases
GeneTreei | ENSGT00400000022095. |
HOGENOMi | HOG000112500. |
InParanoidi | P53917. |
OMAi | NNSFEQD. |
OrthoDBi | EOG092C0SB3. |
Family and domain databases
InterProi | View protein in InterPro IPR021819. Far11/STRP_C. IPR012486. Far11/STRP_N. |
Pfami | View protein in Pfam PF11882. DUF3402. 2 hits. PF07923. N1221. 1 hit. |
SMARTi | View protein in SMART SM01293. DUF3402. 1 hit. SM01292. N1221. 1 hit. |
i Sequence
Sequence statusi: Complete.
P53917-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNASGRSHSK GPIIRSVSLE DLKRNSSFKG NLKYKDEVTS HKEPQVGTLS
60 70 80 90 100
NEELLKDLDN MLRGKLNMGR NSFHADKRNK SDGNISALTF KARSGLEGDI
110 120 130 140 150
RTIDIQQDSS DENDNFKFSD DGVNKDRNNE KDNNTDNAVE FQDDAEEAEE
160 170 180 190 200
ENEDESFANV DELDGFDLNK VSDGKHVPIN EKGEVDYNMP VDKEFQKSLD
210 220 230 240 250
QCAASLEERS SAPYALQRAV DWELKMFYSL EDELSEWFCS SDYMHFGQTQ
260 270 280 290 300
TLFKQKITQP QLFFDDENYA ASVVECLIED IPNSLASNLL ALSYISMGCF
310 320 330 340 350
AFTNSKSEHT KIIRRNNLML VPHIQEIVHA FKKIAISCRD DNRNLKKQTI
360 370 380 390 400
LLFHSSTILY FICSICIEGR GENPEAVNVV IDAFEKTDLL EFLTKYIENW
410 420 430 440 450
RWNSRLAMRI RNMISLLFKL IVLQFGDSSV YKQTKSSIYN LHGLTYPSKH
460 470 480 490 500
PEKLSISPLH YQAFREDITS RFPDYNMPSS GLPKDVDKSE SLSQFLEIPR
510 520 530 540 550
PKSKNPLNMA LIVPEKHIAT PAPSPPSSPQ LMHLGEGPRP RKSFQTNMAY
560 570 580 590 600
PCLYPSDNEG SEDDTLEDRI DLNIERKPDN DIVIPFSTEE AARILSESLE
610 620 630 640 650
IKLSTKQLWY ERDLFMITER GWKQQLENEP YDYAALNHDA NSSKEEKSAI
660 670 680 690 700
CIMQRIDKYY KSCLSSFNSL VFVLLQTMES SLTNNFHRKS EVSDKNLLNM
710 720 730 740 750
LTPQLEIVRA KELSLKSAAG ILHALLKWFK LSHILKFEHL AVVIHDSRYI
760 770 780 790 800
NTCASILSKY SEVYPERVFN KYVQTPNSFW KECSLSNESY RESYSVDDSG
810 820 830 840 850
EVDTEIMPSF AYLLRILRKV TGNKTQRLKE LPLSIGILFK RYYRLFNLDM
860 870 880 890 900
YHPILKITRE LTPFKNKRWK SEHMELISGV YLYEKLELTD NWVTGKDISG
910 920 930 940 950
ELSDACGQEI ALRALLQFYN FQHYEISMED LGYGHRNSSS QDLLNKESEY
LNI
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z46843 Genomic DNA. Translation: CAA86898.1. Z71402 Genomic DNA. Translation: CAA96008.1. Z71403 Genomic DNA. Translation: CAA96009.1. Z69382 Genomic DNA. Translation: CAA93376.1. BK006947 Genomic DNA. Translation: DAA10422.1. |
PIRi | S55156. |
RefSeqi | NP_014272.3. NM_001182965.3. |
Genome annotation databases
EnsemblFungii | YNL127W; YNL127W; YNL127W. |
GeneIDi | 855596. |
KEGGi | sce:YNL127W. |
Similar proteinsi
Entry informationi
Entry namei | FAR11_YEAST | |
Accessioni | P53917Primary (citable) accession number: P53917 Secondary accession number(s): D6W156 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 1, 1996 |
Last sequence update: | October 1, 1996 | |
Last modified: | March 28, 2018 | |
This is version 139 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |