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Protein

Factor arrest protein 11

Gene

FAR11

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Participates in the control of the reentry into the cell cycle following pheromone treatment.2 Publications

Miscellaneous

Present with 1080 molecules/cell in log phase SD medium.1 Publication

GO - Biological processi

  • intra-S DNA damage checkpoint Source: SGD
  • positive regulation of macroautophagy Source: SGD
  • re-entry into mitotic cell cycle after pheromone arrest Source: SGD

Keywordsi

Biological processCell cycle

Enzyme and pathway databases

BioCyciYEAST:G3O-33148-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Factor arrest protein 11
Gene namesi
Name:FAR11
Ordered Locus Names:YNL127W
ORF Names:N1221, N1875
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIV

Organism-specific databases

EuPathDBiFungiDB:YNL127W
SGDiS000005071 FAR11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000871901 – 953Factor arrest protein 11Add BLAST953

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei18PhosphoserineCombined sources1
Modified residuei81PhosphoserineCombined sources1
Modified residuei524PhosphoserineCombined sources1
Modified residuei527PhosphoserineCombined sources1
Modified residuei528PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP53917
PaxDbiP53917
PRIDEiP53917

PTM databases

iPTMnetiP53917

Interactioni

Subunit structurei

Component of a complex at least composed of FAR3, FAR7, FAR8, FAR10, FAR11 and VPS64.

Binary interactionsi

WithEntry#Exp.IntActNotes
FAR3P466712EBI-28900,EBI-6789

Protein-protein interaction databases

BioGridi35700, 256 interactors
ComplexPortaliCPX-1197 FAR complex
DIPiDIP-1830N
IntActiP53917, 21 interactors
MINTiP53917
STRINGi4932.YNL127W

Structurei

3D structure databases

ProteinModelPortaliP53917
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAR11 family.Curated

Phylogenomic databases

GeneTreeiENSGT00400000022095
HOGENOMiHOG000112500
InParanoidiP53917
OMAiNNSFEQD
OrthoDBiEOG092C0SB3

Family and domain databases

InterProiView protein in InterPro
IPR021819 Far11/STRP_C
IPR012486 Far11/STRP_N
PfamiView protein in Pfam
PF11882 DUF3402, 2 hits
PF07923 N1221, 1 hit
SMARTiView protein in SMART
SM01293 DUF3402, 1 hit
SM01292 N1221, 1 hit

Sequencei

Sequence statusi: Complete.

P53917-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNASGRSHSK GPIIRSVSLE DLKRNSSFKG NLKYKDEVTS HKEPQVGTLS
60 70 80 90 100
NEELLKDLDN MLRGKLNMGR NSFHADKRNK SDGNISALTF KARSGLEGDI
110 120 130 140 150
RTIDIQQDSS DENDNFKFSD DGVNKDRNNE KDNNTDNAVE FQDDAEEAEE
160 170 180 190 200
ENEDESFANV DELDGFDLNK VSDGKHVPIN EKGEVDYNMP VDKEFQKSLD
210 220 230 240 250
QCAASLEERS SAPYALQRAV DWELKMFYSL EDELSEWFCS SDYMHFGQTQ
260 270 280 290 300
TLFKQKITQP QLFFDDENYA ASVVECLIED IPNSLASNLL ALSYISMGCF
310 320 330 340 350
AFTNSKSEHT KIIRRNNLML VPHIQEIVHA FKKIAISCRD DNRNLKKQTI
360 370 380 390 400
LLFHSSTILY FICSICIEGR GENPEAVNVV IDAFEKTDLL EFLTKYIENW
410 420 430 440 450
RWNSRLAMRI RNMISLLFKL IVLQFGDSSV YKQTKSSIYN LHGLTYPSKH
460 470 480 490 500
PEKLSISPLH YQAFREDITS RFPDYNMPSS GLPKDVDKSE SLSQFLEIPR
510 520 530 540 550
PKSKNPLNMA LIVPEKHIAT PAPSPPSSPQ LMHLGEGPRP RKSFQTNMAY
560 570 580 590 600
PCLYPSDNEG SEDDTLEDRI DLNIERKPDN DIVIPFSTEE AARILSESLE
610 620 630 640 650
IKLSTKQLWY ERDLFMITER GWKQQLENEP YDYAALNHDA NSSKEEKSAI
660 670 680 690 700
CIMQRIDKYY KSCLSSFNSL VFVLLQTMES SLTNNFHRKS EVSDKNLLNM
710 720 730 740 750
LTPQLEIVRA KELSLKSAAG ILHALLKWFK LSHILKFEHL AVVIHDSRYI
760 770 780 790 800
NTCASILSKY SEVYPERVFN KYVQTPNSFW KECSLSNESY RESYSVDDSG
810 820 830 840 850
EVDTEIMPSF AYLLRILRKV TGNKTQRLKE LPLSIGILFK RYYRLFNLDM
860 870 880 890 900
YHPILKITRE LTPFKNKRWK SEHMELISGV YLYEKLELTD NWVTGKDISG
910 920 930 940 950
ELSDACGQEI ALRALLQFYN FQHYEISMED LGYGHRNSSS QDLLNKESEY

LNI
Length:953
Mass (Da):109,793
Last modified:October 1, 1996 - v1
Checksum:i0FA7B36B181D97A3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z46843 Genomic DNA Translation: CAA86898.1
Z71402 Genomic DNA Translation: CAA96008.1
Z71403 Genomic DNA Translation: CAA96009.1
Z69382 Genomic DNA Translation: CAA93376.1
BK006947 Genomic DNA Translation: DAA10422.1
PIRiS55156
RefSeqiNP_014272.3, NM_001182965.3

Genome annotation databases

EnsemblFungiiYNL127W; YNL127W; YNL127W
GeneIDi855596
KEGGisce:YNL127W

Similar proteinsi

Entry informationi

Entry nameiFAR11_YEAST
AccessioniPrimary (citable) accession number: P53917
Secondary accession number(s): D6W156
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: June 20, 2018
This is version 141 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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