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Protein

Uncharacterized mitochondrial hydrolase FMP41

Gene

FMP41

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi87Divalent metal cationBy similarity1
Metal bindingi89Divalent metal cationBy similarity1
Metal bindingi121Divalent metal cationBy similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Stress response

Keywords - Ligandi

Metal-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-33184-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized mitochondrial hydrolase FMP41 (EC:3.-.-.-)
Gene namesi
Name:FMP41
Ordered Locus Names:YNL168C
ORF Names:N1696
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIV

Organism-specific databases

EuPathDBiFungiDB:YNL168C.
SGDiS000005112. FMP41.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001568431 – 259Uncharacterized mitochondrial hydrolase FMP41Add BLAST259

Proteomic databases

MaxQBiP53889.
PRIDEiP53889.

Expressioni

Inductioni

In high salinity conditions.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi35660. 8 interactors.
IntActiP53889. 10 interactors.
MINTiMINT-2493962.

Structurei

Secondary structure

1259
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi4 – 8Combined sources5
Beta strandi12 – 15Combined sources4
Helixi23 – 27Combined sources5
Beta strandi36 – 39Combined sources4
Helixi41 – 43Combined sources3
Beta strandi44 – 46Combined sources3
Beta strandi76 – 78Combined sources3
Beta strandi84 – 86Combined sources3
Beta strandi88 – 94Combined sources7
Helixi106 – 108Combined sources3
Helixi110 – 112Combined sources3
Beta strandi113 – 120Combined sources8
Helixi125 – 134Combined sources10
Helixi139 – 143Combined sources5
Beta strandi148 – 150Combined sources3
Helixi156 – 162Combined sources7
Turni167 – 169Combined sources3
Beta strandi170 – 176Combined sources7
Beta strandi179 – 185Combined sources7
Helixi186 – 188Combined sources3
Beta strandi189 – 191Combined sources3
Helixi193 – 201Combined sources9
Beta strandi211 – 213Combined sources3
Beta strandi221 – 223Combined sources3
Beta strandi228 – 235Combined sources8
Beta strandi238 – 249Combined sources12

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1NKQX-ray2.20A/B/C/D/E/F1-259[»]
ProteinModelPortaliP53889.
SMRiP53889.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP53889.

Family & Domainsi

Sequence similaritiesi

Belongs to the FAH family.Curated

Phylogenomic databases

GeneTreeiENSGT00530000063832.
HOGENOMiHOG000063753.
InParanoidiP53889.
OMAiVVSMRFK.
OrthoDBiEOG092C4XMI.

Family and domain databases

Gene3Di3.90.850.10. 1 hit.
InterProiIPR011234. Fumarylacetoacetase_C-rel.
[Graphical view]
PfamiPF01557. FAA_hydrolase. 1 hit.
[Graphical view]
SUPFAMiSSF56529. SSF56529. 1 hit.

Sequencei

Sequence statusi: Complete.

P53889-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYNYLKAAR KIICIGRNYA AHIKELNNST PKQPFFFLKP TSSIVTPLSS
60 70 80 90 100
SLVKTTRPAN STFNGLNEDG TNPGPIFIPR GVKVHHEIEL ALIVSKHLSN
110 120 130 140 150
VTKMKPEEVY DSISGVALAL DLTARNVQDE AKKKGLPWTI SKGFDTFMPI
160 170 180 190 200
SAIVSREKFS SYKSNLQDIF RVKCSVNGQL RQDGGTNLML HPLHKILQHI
210 220 230 240 250
STMISLEPGD IILTGTPAGV GELKPGDRVH CELLQNNDNI VDMNFECENR

PGPYEFRET
Length:259
Mass (Da):28,792
Last modified:October 1, 1996 - v1
Checksum:i6984B5BAB297CECC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X92517 Genomic DNA. Translation: CAA63271.1.
Z71444 Genomic DNA. Translation: CAA96055.1.
BK006947 Genomic DNA. Translation: DAA10380.1.
PIRiS60959.
RefSeqiNP_014231.1. NM_001183006.1.

Genome annotation databases

EnsemblFungiiYNL168C; YNL168C; YNL168C.
GeneIDi855553.
KEGGisce:YNL168C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X92517 Genomic DNA. Translation: CAA63271.1.
Z71444 Genomic DNA. Translation: CAA96055.1.
BK006947 Genomic DNA. Translation: DAA10380.1.
PIRiS60959.
RefSeqiNP_014231.1. NM_001183006.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1NKQX-ray2.20A/B/C/D/E/F1-259[»]
ProteinModelPortaliP53889.
SMRiP53889.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi35660. 8 interactors.
IntActiP53889. 10 interactors.
MINTiMINT-2493962.

Proteomic databases

MaxQBiP53889.
PRIDEiP53889.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYNL168C; YNL168C; YNL168C.
GeneIDi855553.
KEGGisce:YNL168C.

Organism-specific databases

EuPathDBiFungiDB:YNL168C.
SGDiS000005112. FMP41.

Phylogenomic databases

GeneTreeiENSGT00530000063832.
HOGENOMiHOG000063753.
InParanoidiP53889.
OMAiVVSMRFK.
OrthoDBiEOG092C4XMI.

Enzyme and pathway databases

BioCyciYEAST:G3O-33184-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP53889.
PROiP53889.

Family and domain databases

Gene3Di3.90.850.10. 1 hit.
InterProiIPR011234. Fumarylacetoacetase_C-rel.
[Graphical view]
PfamiPF01557. FAA_hydrolase. 1 hit.
[Graphical view]
SUPFAMiSSF56529. SSF56529. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiFMP41_YEAST
AccessioniPrimary (citable) accession number: P53889
Secondary accession number(s): D6W114
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: November 2, 2016
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 2550 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome XIV
    Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.