Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Nucleolar protein 13

Gene

NOP13

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • nucleotide binding Source: InterPro
  • RNA binding Source: SGD
Complete GO annotation...

Keywords - Ligandi

RNA-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-33187-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleolar protein 13
Gene namesi
Name:NOP13
Ordered Locus Names:YNL175C
ORF Names:N1665
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIV

Organism-specific databases

EuPathDBiFungiDB:YNL175C.
SGDiS000005119. NOP13.

Subcellular locationi

GO - Cellular componenti

  • nucleolus Source: SGD
  • preribosome Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedCombined sources
ChainiPRO_00000820362 – 403Nucleolar protein 13Add BLAST402

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserineCombined sources1
Modified residuei2PhosphoserineCombined sources1
Modified residuei105PhosphothreonineCombined sources1
Modified residuei335PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiP53883.
PRIDEiP53883.

PTM databases

iPTMnetiP53883.

Interactioni

Protein-protein interaction databases

BioGridi35656. 85 interactors.
DIPiDIP-4331N.
IntActiP53883. 70 interactors.
MINTiMINT-479067.

Structurei

3D structure databases

ProteinModelPortaliP53883.
SMRiP53883.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini125 – 219RRM 1PROSITE-ProRule annotationAdd BLAST95
Domaini239 – 317RRM 2PROSITE-ProRule annotationAdd BLAST79

Sequence similaritiesi

Contains 2 RRM (RNA recognition motif) domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

GeneTreeiENSGT00860000133811.
HOGENOMiHOG000193653.
InParanoidiP53883.
OMAiCRKIAGR.
OrthoDBiEOG092C3SCB.

Family and domain databases

Gene3Di3.30.70.330. 2 hits.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 1 hit.
[Graphical view]
SMARTiSM00360. RRM. 2 hits.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 2 hits.
PROSITEiPS50102. RRM. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P53883-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSETELSKED AVTKKDNEEQ VKKALLDPTK KRKAEDEIEI DLKSSIPLSK
60 70 80 90 100
KQKRLLRRGK VTLEELNAKY NIDPKSIEEY KEDAEKKKSG ASEKDAQGEE
110 120 130 140 150
STINTPTGDE SGEVVKKKKK DENKYGVWIG NLSFDTTKDD LVRFFIAKTK
160 170 180 190 200
DNEDEKSRVT EQDITRLSMP RVAAKNSNAM KNKGFCYMFF KNVEQMKAVL
210 220 230 240 250
ELSESHLNGR NMLIKDSENY SGRPDKDDLV AMSKNPPSRI LFVGNLSFDV
260 270 280 290 300
TDDLLRKHFQ HCGDIVKIRM ATFEDSGKCK GFAFIDFKNE EGSTNALKDK
310 320 330 340 350
SCRKIAGRPL RMEYGEDRSK RQVRKKVENV SRNNSSSFDI SNNKGYDRAG
360 370 380 390 400
QDNGSKPEYK RSNANRRPPV DSNNRTKSSV ALATAQRGSA AIVPSQGKKV

KFD
Length:403
Mass (Da):45,609
Last modified:September 21, 2011 - v2
Checksum:iFB1A0FB46B13C201
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti296A → E in CAA96066 (PubMed:9169873).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z71451 Genomic DNA. Translation: CAA96066.1.
BK006947 Genomic DNA. Translation: DAA10376.2.
PIRiS63130.
RefSeqiNP_014224.2. NM_001183013.2.

Genome annotation databases

EnsemblFungiiYNL175C; YNL175C; YNL175C.
GeneIDi855547.
KEGGisce:YNL175C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z71451 Genomic DNA. Translation: CAA96066.1.
BK006947 Genomic DNA. Translation: DAA10376.2.
PIRiS63130.
RefSeqiNP_014224.2. NM_001183013.2.

3D structure databases

ProteinModelPortaliP53883.
SMRiP53883.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi35656. 85 interactors.
DIPiDIP-4331N.
IntActiP53883. 70 interactors.
MINTiMINT-479067.

PTM databases

iPTMnetiP53883.

Proteomic databases

MaxQBiP53883.
PRIDEiP53883.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYNL175C; YNL175C; YNL175C.
GeneIDi855547.
KEGGisce:YNL175C.

Organism-specific databases

EuPathDBiFungiDB:YNL175C.
SGDiS000005119. NOP13.

Phylogenomic databases

GeneTreeiENSGT00860000133811.
HOGENOMiHOG000193653.
InParanoidiP53883.
OMAiCRKIAGR.
OrthoDBiEOG092C3SCB.

Enzyme and pathway databases

BioCyciYEAST:G3O-33187-MONOMER.

Miscellaneous databases

PROiP53883.

Family and domain databases

Gene3Di3.30.70.330. 2 hits.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 1 hit.
[Graphical view]
SMARTiSM00360. RRM. 2 hits.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 2 hits.
PROSITEiPS50102. RRM. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiNOP13_YEAST
AccessioniPrimary (citable) accession number: P53883
Secondary accession number(s): D6W110
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: September 21, 2011
Last modified: November 30, 2016
This is version 136 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 3830 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XIV
    Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.