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Protein

Uncharacterized oxidoreductase YNL181W

Gene

YNL181W

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi57 – 79NAD or NADPBy similarityAdd BLAST23

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciYEAST:G3O-33192-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized oxidoreductase YNL181W (EC:1.-.-.-)
Gene namesi
Ordered Locus Names:YNL181W
ORF Names:N1640
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIV

Organism-specific databases

EuPathDBiFungiDB:YNL181W.
SGDiS000005125. YNL181W.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 290LumenalSequence analysisAdd BLAST290
Transmembranei291 – 311HelicalSequence analysisAdd BLAST21
Topological domaini312 – 407CytoplasmicSequence analysisAdd BLAST96

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002034051 – 407Uncharacterized oxidoreductase YNL181WAdd BLAST407

Proteomic databases

MaxQBiP53878.
PRIDEiP53878.

Interactioni

Protein-protein interaction databases

BioGridi35651. 70 interactors.
DIPiDIP-6413N.
IntActiP53878. 1 interactor.
MINTiMINT-4500218.

Structurei

3D structure databases

ProteinModelPortaliP53878.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili361 – 390Sequence analysisAdd BLAST30

Sequence similaritiesi

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000175307.
InParanoidiP53878.
OMAiTSQGMGT.
OrthoDBiEOG092C2OEI.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR002347. SDR_fam.
[Graphical view]
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
SUPFAMiSSF51735. SSF51735. 1 hit.

Sequencei

Sequence statusi: Complete.

P53878-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLNIIGTAL LDGTDKIPYY QTIKKVAPYV LATGAIKYWS RGPSNTWERK
60 70 80 90 100
LHGKVYLVTG ATSQGMGTSV AYKMAELGAQ LIILTREVDE WVTEWCEELR
110 120 130 140 150
EKTKNELIFV EKCDLSNLWE IRKFATSWLD NSPPRRLDGV IVMSGDMEPW
160 170 180 190 200
GIPKISLPQR RSSKDGLELQ IATNYVAIFH LLNLLQPSFK AQPPDRDVRI
210 220 230 240 250
ILATCWLQVV GDINIEDPLW QNAKYKSALK FFASSKLQLG LSMMELQRRL
260 270 280 290 300
TEDIKNQKTN GAERTGKNVT ITMVQPGTMR SNSLRRVISN GSVVLLIILY
310 320 330 340 350
CILLYPILWL FTKSGRRGDQ SFLYALMTPE LEEVNLKDTK VKYISDCSIV
360 370 380 390 400
KFARKEFDDE ELQKKLFDNT ERDILQLEKK VAAKRNANKT GNQNSKKKSQ

NKSRKDD
Length:407
Mass (Da):46,503
Last modified:September 21, 2011 - v2
Checksum:iE57B677EB79BC2C9
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti262A → P in CAA96073 (PubMed:9169873).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z71457 Genomic DNA. Translation: CAA96073.1.
BK006947 Genomic DNA. Translation: DAA10371.2.
PIRiS63136.
RefSeqiNP_014218.2. NM_001183019.2.

Genome annotation databases

EnsemblFungiiYNL181W; YNL181W; YNL181W.
GeneIDi855540.
KEGGisce:YNL181W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z71457 Genomic DNA. Translation: CAA96073.1.
BK006947 Genomic DNA. Translation: DAA10371.2.
PIRiS63136.
RefSeqiNP_014218.2. NM_001183019.2.

3D structure databases

ProteinModelPortaliP53878.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi35651. 70 interactors.
DIPiDIP-6413N.
IntActiP53878. 1 interactor.
MINTiMINT-4500218.

Proteomic databases

MaxQBiP53878.
PRIDEiP53878.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYNL181W; YNL181W; YNL181W.
GeneIDi855540.
KEGGisce:YNL181W.

Organism-specific databases

EuPathDBiFungiDB:YNL181W.
SGDiS000005125. YNL181W.

Phylogenomic databases

HOGENOMiHOG000175307.
InParanoidiP53878.
OMAiTSQGMGT.
OrthoDBiEOG092C2OEI.

Enzyme and pathway databases

BioCyciYEAST:G3O-33192-MONOMER.

Miscellaneous databases

PROiP53878.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR002347. SDR_fam.
[Graphical view]
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
SUPFAMiSSF51735. SSF51735. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYNS1_YEAST
AccessioniPrimary (citable) accession number: P53878
Secondary accession number(s): D6W105
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: September 21, 2011
Last modified: November 2, 2016
This is version 119 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 13900 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XIV
    Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.