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Protein

Protein SWT21

Gene

SWT21

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in mRNA splicing. Helps to stabilize the U1 snRNP-5' splice site interaction.1 Publication

GO - Biological processi

  • mRNA splicing, via spliceosome Source: SGD

Keywordsi

Biological processmRNA processing, mRNA splicing

Enzyme and pathway databases

BioCyciYEAST:G3O-33198-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein SWT21
Alternative name(s):
Synthetic With TGS1 protein 21
Gene namesi
Name:SWT21
Ordered Locus Names:YNL187W
ORF Names:N1615
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIV

Organism-specific databases

EuPathDBiFungiDB:YNL187W
SGDiS000005131 SWT21

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002034031 – 357Protein SWT21Add BLAST357

Proteomic databases

PaxDbiP53873

Interactioni

Subunit structurei

Associates with snRNPs.

Protein-protein interaction databases

BioGridi35646, 22 interactors
DIPiDIP-971N
IntActiP53873, 4 interactors
MINTiP53873
STRINGi4932.YNL187W

Structurei

3D structure databases

ProteinModelPortaliP53873
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SWT21 family.Curated

Phylogenomic databases

InParanoidiP53873
OMAiICQDIFW
OrthoDBiEOG092C4YKL

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR036322 WD40_repeat_dom_sf
SUPFAMiSSF50978 SSF50978, 1 hit

Sequencei

Sequence statusi: Complete.

P53873-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKKVICQDI FWSCDGTSFV SVHNDFGIRQ YLVPEESNTD KLNRNLLLPF
60 70 80 90 100
TRFFRNQSIV SCAIDPFYTL YNENSDRLAG DRIVVGGKNF PLQLYSLMDG
110 120 130 140 150
QCILSYDTMN KINGEYETVY SVKIDVESRV YTGSCRNKVA IYDKSRRDAV
160 170 180 190 200
WMNQSTKKAS KGRQSIISCF EEQPMGGQAL SRGSLLCGSY ANEMFQVDCR
210 220 230 240 250
HQRLERLNYT RTVAGGIVQI LTSDNGRYVY VVRRNSDAIS IYDRRNLQHE
260 270 280 290 300
LNVLRLPFRI HHNSAKLKAY IDTAYGLSMG TPQGTILNWG RDLVEFGGVP
310 320 330 340 350
SHNSVEDPLI TSIPPESEWR TNLDSTIPAT VVKNCPGDPE LFALSHGGTI

SLCRFGG
Length:357
Mass (Da):40,308
Last modified:October 1, 1996 - v1
Checksum:iED52B00C4902453A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z71463 Genomic DNA Translation: CAA96081.1
BK006947 Genomic DNA Translation: DAA10366.1
PIRiS63142
RefSeqiNP_014212.1, NM_001183025.1

Genome annotation databases

EnsemblFungiiYNL187W; YNL187W; YNL187W
GeneIDi855534
KEGGisce:YNL187W

Similar proteinsi

Entry informationi

Entry nameiSWT21_YEAST
AccessioniPrimary (citable) accession number: P53873
Secondary accession number(s): D6W100
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: March 28, 2018
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health