Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

J protein JJJ1

Gene

JJJ1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri338 – 36225C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri549 – 57325C2H2-type 2PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. ATPase activator activity Source: SGD
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. endocytosis Source: SGD
  2. positive regulation of ATPase activity Source: GOC
  3. ribosomal large subunit biogenesis Source: SGD
  4. ribosomal subunit export from nucleus Source: SGD
  5. rRNA processing Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciYEAST:G3O-33229-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
J protein JJJ1
Gene namesi
Name:JJJ1
Ordered Locus Names:YNL227C
ORF Names:N1254
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome XIV

Organism-specific databases

CYGDiYNL227c.
SGDiS000005171. JJJ1.

Subcellular locationi

Nucleus Curated

GO - Cellular componenti

  1. cytoplasm Source: SGD
  2. cytosol Source: SGD
  3. nucleolus Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 590590J protein JJJ1PRO_0000071162Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei393 – 3931Phosphoserine1 Publication
Modified residuei504 – 5041Phosphothreonine3 Publications

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP53863.
PaxDbiP53863.

Expressioni

Gene expression databases

GenevestigatoriP53863.

Interactioni

Protein-protein interaction databases

BioGridi35610. 117 interactions.
DIPiDIP-972N.
IntActiP53863. 21 interactions.
MINTiMINT-424101.
STRINGi4932.YNL227C.

Structurei

3D structure databases

ProteinModelPortaliP53863.
SMRiP53863. Positions 5-67.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini3 – 7270JPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 2 C2H2-type zinc fingers.PROSITE-ProRule annotation
Contains 1 J domain.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri338 – 36225C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri549 – 57325C2H2-type 2PROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiCOG2214.
GeneTreeiENSGT00510000047097.
HOGENOMiHOG000193307.
InParanoidiP53863.
KOiK09506.
OMAiGDSTWPW.
OrthoDBiEOG78PVMP.

Family and domain databases

Gene3Di1.10.287.110. 1 hit.
InterProiIPR001623. DnaJ_domain.
IPR018253. DnaJ_domain_CS.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR022755. Znf_C2H2_jaz.
[Graphical view]
PfamiPF00226. DnaJ. 1 hit.
PF12171. zf-C2H2_jaz. 1 hit.
[Graphical view]
PRINTSiPR00625. JDOMAIN.
SMARTiSM00271. DnaJ. 1 hit.
SM00355. ZnF_C2H2. 2 hits.
[Graphical view]
SUPFAMiSSF46565. SSF46565. 1 hit.
PROSITEiPS00636. DNAJ_1. 1 hit.
PS50076. DNAJ_2. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 2 hits.
PS50157. ZINC_FINGER_C2H2_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P53863-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKTCYYELLG VETHASDLEL KKAYRKKALQ YHPDKNPDNV EEATQKFAVI
60 70 80 90 100
RAAYEVLSDP QERAWYDSHK EQILNDTPPS TDDYYDYEVD ATVTGVTTDE
110 120 130 140 150
LLLFFNSALY TKIDNSAAGI YQIAGKIFAK LAKDEILSGK RLGKFSEYQD
160 170 180 190 200
DVFEQDINSI GYLKACDNFI NKTDKLLYPL FGYSPTDYEY LKHFYKTWSA
210 220 230 240 250
FNTLKSFSWK DEYMYSKNYD RRTKREVNRR NEKARQQARN EYNKTVKRFV
260 270 280 290 300
VFIKKLDKRM KEGAKIAEEQ RKLKEQQRKN ELNNRRKFGN DNNDEEKFHL
310 320 330 340 350
QSWQTVKEEN WDELEKVYDN FGEFENSKND KEGEVLIYEC FICNKTFKSE
360 370 380 390 400
KQLKNHINTK LHKKNMEEIR KEMEEENITL GLDNLSDLEK FDSADESVKE
410 420 430 440 450
KEDIDLQALQ AELAEIERKL AESSSEDESE DDNLNIEMDI EVEDVSSDEN
460 470 480 490 500
VHVNTKNKKK RKKKKKAKVD TETEESESFD DTKDKRSNEL DDLLASLGDK
510 520 530 540 550
GLQTDDDEDW STKAKKKKGK QPKKNSKSTK STPSLSTLPS SMSPTSAIEV
560 570 580 590
CTTCGESFDS RNKLFNHVKI AGHAAVKNVV KRKKVKTKRI
Length:590
Mass (Da):68,783
Last modified:October 1, 1996 - v1
Checksum:i0D184EF861105C95
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z69381 Genomic DNA. Translation: CAA93371.1.
Z71504 Genomic DNA. Translation: CAA96132.1.
BK006947 Genomic DNA. Translation: DAA10330.1.
PIRiS63193.
RefSeqiNP_014172.1. NM_001183065.1.

Genome annotation databases

EnsemblFungiiYNL227C; YNL227C; YNL227C.
GeneIDi855495.
KEGGisce:YNL227C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z69381 Genomic DNA. Translation: CAA93371.1.
Z71504 Genomic DNA. Translation: CAA96132.1.
BK006947 Genomic DNA. Translation: DAA10330.1.
PIRiS63193.
RefSeqiNP_014172.1. NM_001183065.1.

3D structure databases

ProteinModelPortaliP53863.
SMRiP53863. Positions 5-67.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi35610. 117 interactions.
DIPiDIP-972N.
IntActiP53863. 21 interactions.
MINTiMINT-424101.
STRINGi4932.YNL227C.

Proteomic databases

MaxQBiP53863.
PaxDbiP53863.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYNL227C; YNL227C; YNL227C.
GeneIDi855495.
KEGGisce:YNL227C.

Organism-specific databases

CYGDiYNL227c.
SGDiS000005171. JJJ1.

Phylogenomic databases

eggNOGiCOG2214.
GeneTreeiENSGT00510000047097.
HOGENOMiHOG000193307.
InParanoidiP53863.
KOiK09506.
OMAiGDSTWPW.
OrthoDBiEOG78PVMP.

Enzyme and pathway databases

BioCyciYEAST:G3O-33229-MONOMER.

Miscellaneous databases

NextBioi979481.
PROiP53863.

Gene expression databases

GenevestigatoriP53863.

Family and domain databases

Gene3Di1.10.287.110. 1 hit.
InterProiIPR001623. DnaJ_domain.
IPR018253. DnaJ_domain_CS.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR022755. Znf_C2H2_jaz.
[Graphical view]
PfamiPF00226. DnaJ. 1 hit.
PF12171. zf-C2H2_jaz. 1 hit.
[Graphical view]
PRINTSiPR00625. JDOMAIN.
SMARTiSM00271. DnaJ. 1 hit.
SM00355. ZnF_C2H2. 2 hits.
[Graphical view]
SUPFAMiSSF46565. SSF46565. 1 hit.
PROSITEiPS00636. DNAJ_1. 1 hit.
PS50076. DNAJ_2. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 2 hits.
PS50157. ZINC_FINGER_C2H2_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence of cosmid 14-5 from chromosome XIV reveals 21 open reading frames including a novel gene encoding a globin-like domain."
    Pandolfo D., de Antoni A., Lanfranchi G., Valle G.
    Yeast 12:1071-1076(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications."
    Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J.
    , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.
    Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  5. "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae."
    Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J., Elias J.E., Gygi S.P.
    J. Proteome Res. 6:1190-1197(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-504, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Strain: ADR376.
  6. "A multidimensional chromatography technology for in-depth phosphoproteome analysis."
    Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
    Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-504, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  7. "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
    Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
    Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-393 AND THR-504, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiJJJ1_YEAST
AccessioniPrimary (citable) accession number: P53863
Secondary accession number(s): D6W0W4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: January 7, 2015
This is version 121 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 2310 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XIV
    Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.