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P53863

- JJJ1_YEAST

UniProt

P53863 - JJJ1_YEAST

Protein

J protein JJJ1

Gene

JJJ1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 118 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
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    Functioni

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri338 – 36225C2H2-type 1PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri549 – 57325C2H2-type 2PROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. ATPase activator activity Source: SGD
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. endocytosis Source: SGD
    2. positive regulation of ATPase activity Source: GOC
    3. ribosomal large subunit biogenesis Source: SGD
    4. ribosomal subunit export from nucleus Source: SGD
    5. rRNA processing Source: SGD

    Keywords - Molecular functioni

    Chaperone

    Keywords - Ligandi

    Metal-binding, Zinc

    Enzyme and pathway databases

    BioCyciYEAST:G3O-33229-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    J protein JJJ1
    Gene namesi
    Name:JJJ1
    Ordered Locus Names:YNL227C
    ORF Names:N1254
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome XIV

    Organism-specific databases

    CYGDiYNL227c.
    SGDiS000005171. JJJ1.

    Subcellular locationi

    Nucleus Curated

    GO - Cellular componenti

    1. cytoplasm Source: SGD
    2. cytosol Source: SGD
    3. nucleolus Source: SGD

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 590590J protein JJJ1PRO_0000071162Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei393 – 3931Phosphoserine1 Publication
    Modified residuei504 – 5041Phosphothreonine3 Publications

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiP53863.
    PaxDbiP53863.

    Expressioni

    Gene expression databases

    GenevestigatoriP53863.

    Interactioni

    Protein-protein interaction databases

    BioGridi35610. 118 interactions.
    DIPiDIP-972N.
    IntActiP53863. 21 interactions.
    MINTiMINT-424101.
    STRINGi4932.YNL227C.

    Structurei

    3D structure databases

    ProteinModelPortaliP53863.
    SMRiP53863. Positions 5-67.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini3 – 7270JPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 2 C2H2-type zinc fingers.PROSITE-ProRule annotation
    Contains 1 J domain.PROSITE-ProRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri338 – 36225C2H2-type 1PROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri549 – 57325C2H2-type 2PROSITE-ProRule annotationAdd
    BLAST

    Keywords - Domaini

    Repeat, Zinc-finger

    Phylogenomic databases

    eggNOGiCOG2214.
    GeneTreeiENSGT00510000047097.
    HOGENOMiHOG000193307.
    KOiK09506.
    OMAiGDSTWPW.
    OrthoDBiEOG78PVMP.

    Family and domain databases

    Gene3Di1.10.287.110. 1 hit.
    InterProiIPR001623. DnaJ_domain.
    IPR018253. DnaJ_domain_CS.
    IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR022755. Znf_C2H2_jaz.
    [Graphical view]
    PfamiPF00226. DnaJ. 1 hit.
    PF12171. zf-C2H2_jaz. 1 hit.
    [Graphical view]
    PRINTSiPR00625. JDOMAIN.
    SMARTiSM00271. DnaJ. 1 hit.
    SM00355. ZnF_C2H2. 2 hits.
    [Graphical view]
    SUPFAMiSSF46565. SSF46565. 1 hit.
    PROSITEiPS00636. DNAJ_1. 1 hit.
    PS50076. DNAJ_2. 1 hit.
    PS00028. ZINC_FINGER_C2H2_1. 2 hits.
    PS50157. ZINC_FINGER_C2H2_2. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P53863-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKTCYYELLG VETHASDLEL KKAYRKKALQ YHPDKNPDNV EEATQKFAVI    50
    RAAYEVLSDP QERAWYDSHK EQILNDTPPS TDDYYDYEVD ATVTGVTTDE 100
    LLLFFNSALY TKIDNSAAGI YQIAGKIFAK LAKDEILSGK RLGKFSEYQD 150
    DVFEQDINSI GYLKACDNFI NKTDKLLYPL FGYSPTDYEY LKHFYKTWSA 200
    FNTLKSFSWK DEYMYSKNYD RRTKREVNRR NEKARQQARN EYNKTVKRFV 250
    VFIKKLDKRM KEGAKIAEEQ RKLKEQQRKN ELNNRRKFGN DNNDEEKFHL 300
    QSWQTVKEEN WDELEKVYDN FGEFENSKND KEGEVLIYEC FICNKTFKSE 350
    KQLKNHINTK LHKKNMEEIR KEMEEENITL GLDNLSDLEK FDSADESVKE 400
    KEDIDLQALQ AELAEIERKL AESSSEDESE DDNLNIEMDI EVEDVSSDEN 450
    VHVNTKNKKK RKKKKKAKVD TETEESESFD DTKDKRSNEL DDLLASLGDK 500
    GLQTDDDEDW STKAKKKKGK QPKKNSKSTK STPSLSTLPS SMSPTSAIEV 550
    CTTCGESFDS RNKLFNHVKI AGHAAVKNVV KRKKVKTKRI 590
    Length:590
    Mass (Da):68,783
    Last modified:October 1, 1996 - v1
    Checksum:i0D184EF861105C95
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z69381 Genomic DNA. Translation: CAA93371.1.
    Z71504 Genomic DNA. Translation: CAA96132.1.
    BK006947 Genomic DNA. Translation: DAA10330.1.
    PIRiS63193.
    RefSeqiNP_014172.1. NM_001183065.1.

    Genome annotation databases

    EnsemblFungiiYNL227C; YNL227C; YNL227C.
    GeneIDi855495.
    KEGGisce:YNL227C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z69381 Genomic DNA. Translation: CAA93371.1 .
    Z71504 Genomic DNA. Translation: CAA96132.1 .
    BK006947 Genomic DNA. Translation: DAA10330.1 .
    PIRi S63193.
    RefSeqi NP_014172.1. NM_001183065.1.

    3D structure databases

    ProteinModelPortali P53863.
    SMRi P53863. Positions 5-67.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 35610. 118 interactions.
    DIPi DIP-972N.
    IntActi P53863. 21 interactions.
    MINTi MINT-424101.
    STRINGi 4932.YNL227C.

    Proteomic databases

    MaxQBi P53863.
    PaxDbi P53863.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YNL227C ; YNL227C ; YNL227C .
    GeneIDi 855495.
    KEGGi sce:YNL227C.

    Organism-specific databases

    CYGDi YNL227c.
    SGDi S000005171. JJJ1.

    Phylogenomic databases

    eggNOGi COG2214.
    GeneTreei ENSGT00510000047097.
    HOGENOMi HOG000193307.
    KOi K09506.
    OMAi GDSTWPW.
    OrthoDBi EOG78PVMP.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-33229-MONOMER.

    Miscellaneous databases

    NextBioi 979481.
    PROi P53863.

    Gene expression databases

    Genevestigatori P53863.

    Family and domain databases

    Gene3Di 1.10.287.110. 1 hit.
    InterProi IPR001623. DnaJ_domain.
    IPR018253. DnaJ_domain_CS.
    IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    IPR022755. Znf_C2H2_jaz.
    [Graphical view ]
    Pfami PF00226. DnaJ. 1 hit.
    PF12171. zf-C2H2_jaz. 1 hit.
    [Graphical view ]
    PRINTSi PR00625. JDOMAIN.
    SMARTi SM00271. DnaJ. 1 hit.
    SM00355. ZnF_C2H2. 2 hits.
    [Graphical view ]
    SUPFAMi SSF46565. SSF46565. 1 hit.
    PROSITEi PS00636. DNAJ_1. 1 hit.
    PS50076. DNAJ_2. 1 hit.
    PS00028. ZINC_FINGER_C2H2_1. 2 hits.
    PS50157. ZINC_FINGER_C2H2_2. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence of cosmid 14-5 from chromosome XIV reveals 21 open reading frames including a novel gene encoding a globin-like domain."
      Pandolfo D., de Antoni A., Lanfranchi G., Valle G.
      Yeast 12:1071-1076(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications."
      Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J.
      , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.
      Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    3. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    4. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
    5. "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae."
      Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J., Elias J.E., Gygi S.P.
      J. Proteome Res. 6:1190-1197(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-504, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Strain: ADR376.
    6. "A multidimensional chromatography technology for in-depth phosphoproteome analysis."
      Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
      Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-504, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    7. "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
      Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
      Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-393 AND THR-504, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiJJJ1_YEAST
    AccessioniPrimary (citable) accession number: P53863
    Secondary accession number(s): D6W0W4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 118 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 2310 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome XIV
      Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

    External Data

    Dasty 3