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P53862 (YNW8_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
putative uncharacterized membrane protein YNL228W
Gene names
Ordered Locus Names:YNL228W
ORF Names:N1249
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length258 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceUncertain

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein.

Caution

Product of a dubious gene prediction. Almost completely overlaps JJJ1.

Ontologies

Keywords
   Cellular componentMembrane
   DomainSignal
Transmembrane
Transmembrane helix
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2323 Potential
Chain24 – 258235putative uncharacterized membrane protein YNL228W
PRO_0000014339

Regions

Topological domain24 – 6441Cytoplasmic Potential
Transmembrane65 – 8521Helical; Potential
Topological domain86 – 12338Extracellular Potential
Transmembrane124 – 14421Helical; Potential
Topological domain145 – 23086Cytoplasmic Potential
Transmembrane231 – 25121Helical; Potential
Topological domain252 – 2587Extracellular Potential
Compositional bias79 – 824Poly-Phe
Compositional bias88 – 925Poly-Ser
Compositional bias129 – 14113Poly-Phe

Amino acid modifications

Glycosylation1181N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
P53862 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: 24F58C70CD10E86C

FASTA25828,642
        10         20         30         40         50         60 
MVWCHYILLV LTFFLFTTFF TAACPAIFTW LNSLFRLSND SPHVVHTSIA EVGDIEDGRV 

        70         80         90        100        110        120 
DKDGVLFVDL EFFLGCLPFF FFALVDQSSS SSVCKPLSPS DAKRSSNSLL RLSLVSSNDS 

       130        140        150        160        170        180 
DSSVSVSTFA FFFFFLFFLF FVFTCTFSSE LTSSTSISIS MLRLSSSLSS SEDDSASFLS 

       190        200        210        220        230        240 
ISASSACNAC RSISSFSLTL SSAESNFSRS ERLSNPSVMF SSSISFRISS IFFLCSLVFM 

       250 
WFFNCFSDLN VLLQIKHS 

« Hide

References

« Hide 'large scale' references
[1]"The DNA sequence of cosmid 14-5 from chromosome XIV reveals 21 open reading frames including a novel gene encoding a globin-like domain."
Pandolfo D., de Antoni A., Lanfranchi G., Valle G.
Yeast 12:1071-1076(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications."
Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J. expand/collapse author list , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.
Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"A global topology map of the Saccharomyces cerevisiae membrane proteome."
Kim H., Melen K., Oesterberg M., von Heijne G.
Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
Strain: ATCC 208353 / W303-1A.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z69381 Genomic DNA. Translation: CAA93370.1.
Z71504 Genomic DNA. Translation: CAA96131.1.
BK006947 Genomic DNA. No translation available.
PIRS63194.

3D structure databases

ProteinModelPortalP53862.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-4282N.
MINTMINT-558266.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYNL228W; YNL228W; YNL228W.

Organism-specific databases

SGDS000005172. YNL228W.

Phylogenomic databases

OrthoDBEOG7966XN.

Gene expression databases

GenevestigatorP53862.

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameYNW8_YEAST
AccessionPrimary (citable) accession number: P53862
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 14, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XIV

Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD