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Protein

Zinc finger protein GIS2

Gene

GIS2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May act in the sexual differentiation pathway.By similarity1 Publication

Miscellaneous

Present with 96655 molecules/cell in log phase SD medium.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri4 – 21CCHC-type 1PROSITE-ProRule annotationAdd BLAST18
Zinc fingeri23 – 40CCHC-type 2PROSITE-ProRule annotationAdd BLAST18
Zinc fingeri47 – 64CCHC-type 3PROSITE-ProRule annotationAdd BLAST18
Zinc fingeri65 – 82CCHC-type 4PROSITE-ProRule annotationAdd BLAST18
Zinc fingeri92 – 109CCHC-type 5PROSITE-ProRule annotationAdd BLAST18
Zinc fingeri116 – 133CCHC-type 6PROSITE-ProRule annotationAdd BLAST18
Zinc fingeri135 – 152CCHC-type 7PROSITE-ProRule annotationAdd BLAST18

GO - Molecular functioni

  • mRNA binding Source: SGD
  • single-stranded DNA binding Source: SGD
  • translation regulator activity Source: SGD
  • zinc ion binding Source: InterPro

GO - Biological processi

  • positive regulation of cytoplasmic translation Source: SGD

Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

BioCyciYEAST:G3O-33252-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein GIS2
Gene namesi
Name:GIS2
Ordered Locus Names:YNL255C
ORF Names:N0852
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIV

Organism-specific databases

EuPathDBiFungiDB:YNL255C
SGDiS000005199 GIS2

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000874961 – 153Zinc finger protein GIS2Add BLAST153

Proteomic databases

MaxQBiP53849
PaxDbiP53849
PRIDEiP53849

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
PAB1P041472EBI-29244,EBI-12823

Protein-protein interaction databases

BioGridi35584, 1234 interactors
DIPiDIP-2669N
IntActiP53849, 20 interactors
MINTiP53849
STRINGi4932.YNL255C

Structurei

3D structure databases

ProteinModelPortaliP53849
SMRiP53849
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri4 – 21CCHC-type 1PROSITE-ProRule annotationAdd BLAST18
Zinc fingeri23 – 40CCHC-type 2PROSITE-ProRule annotationAdd BLAST18
Zinc fingeri47 – 64CCHC-type 3PROSITE-ProRule annotationAdd BLAST18
Zinc fingeri65 – 82CCHC-type 4PROSITE-ProRule annotationAdd BLAST18
Zinc fingeri92 – 109CCHC-type 5PROSITE-ProRule annotationAdd BLAST18
Zinc fingeri116 – 133CCHC-type 6PROSITE-ProRule annotationAdd BLAST18
Zinc fingeri135 – 152CCHC-type 7PROSITE-ProRule annotationAdd BLAST18

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

GeneTreeiENSGT00510000047065
HOGENOMiHOG000186262
InParanoidiP53849
KOiK09250
OMAiIQKDCTQ
OrthoDBiEOG092C2J4N

Family and domain databases

InterProiView protein in InterPro
IPR001878 Znf_CCHC
IPR036875 Znf_CCHC_sf
PfamiView protein in Pfam
PF00098 zf-CCHC, 7 hits
SMARTiView protein in SMART
SM00343 ZnF_C2HC, 7 hits
SUPFAMiSSF57756 SSF57756, 3 hits
PROSITEiView protein in PROSITE
PS50158 ZF_CCHC, 7 hits

Sequencei

Sequence statusi: Complete.

P53849-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQKACYVCG KIGHLAEDCD SERLCYNCNK PGHVQTDCTM PRTVEFKQCY
60 70 80 90 100
NCGETGHVRS ECTVQRCFNC NQTGHISREC PEPKKTSRFS KVSCYKCGGP
110 120 130 140 150
NHMAKDCMKE DGISGLKCYT CGQAGHMSRD CQNDRLCYNC NETGHISKDC

PKA
Length:153
Mass (Da):17,103
Last modified:October 1, 1996 - v1
Checksum:iE72696428F85CA3F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X96722 Genomic DNA Translation: CAA65489.1
Z71531 Genomic DNA Translation: CAA96162.1
AY558002 Genomic DNA Translation: AAS56328.1
BK006947 Genomic DNA Translation: DAA10304.1
PIRiS63228
RefSeqiNP_014144.1, NM_001183093.1

Genome annotation databases

EnsemblFungiiYNL255C; YNL255C; YNL255C
GeneIDi855466
KEGGisce:YNL255C

Similar proteinsi

Entry informationi

Entry nameiGIS2_YEAST
AccessioniPrimary (citable) accession number: P53849
Secondary accession number(s): D6W0T8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 23, 2018
This is version 147 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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