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P53838

- BOR1_YEAST

UniProt

P53838 - BOR1_YEAST

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Protein

Boron transporter 1

Gene
BOR1, YNL275W, N0626
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at protein leveli

Functioni

Functions in boric acid/borate export across the plasma membrane, and thereby protects yeast cells from boron toxicity. Involved in the trafficking of proteins to the vacuole.5 Publications

GO - Molecular functioni

  1. borate efflux transmembrane transporter activity Source: SGD
  2. inorganic anion exchanger activity Source: InterPro

GO - Biological processi

  1. borate transmembrane transport Source: GOC
  2. borate transport Source: SGD
  3. protein targeting to vacuole Source: SGD
Complete GO annotation...

Keywords - Biological processi

Anion exchange, Ion transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-33269-MONOMER.

Protein family/group databases

TCDBi2.A.31.3.2. the anion exchanger (ae) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Boron transporter 1
Gene namesi
Name:BOR1
Ordered Locus Names:YNL275W
ORF Names:N0626
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome XIV

Organism-specific databases

CYGDiYNL275w.
SGDiS000005219. BOR1.

Subcellular locationi

Cell membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein 3 Publications

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 8484Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei85 – 10521Helical; Reviewed predictionAdd
BLAST
Topological domaini106 – 11611Extracellular Reviewed predictionAdd
BLAST
Transmembranei117 – 13418Helical; Reviewed predictionAdd
BLAST
Topological domaini135 – 1406Cytoplasmic Reviewed prediction
Transmembranei141 – 16020Helical; Reviewed predictionAdd
BLAST
Topological domaini161 – 1655Extracellular Reviewed prediction
Transmembranei166 – 18621Helical; Reviewed predictionAdd
BLAST
Topological domaini187 – 1926Cytoplasmic Reviewed prediction
Transmembranei193 – 21321Helical; Reviewed predictionAdd
BLAST
Topological domaini214 – 23522Extracellular Reviewed predictionAdd
BLAST
Transmembranei236 – 25621Helical; Reviewed predictionAdd
BLAST
Topological domaini257 – 27418Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei275 – 29521Helical; Reviewed predictionAdd
BLAST
Topological domaini296 – 32934Extracellular Reviewed predictionAdd
BLAST
Transmembranei330 – 35021Helical; Reviewed predictionAdd
BLAST
Topological domaini351 – 37323Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei374 – 39421Helical; Reviewed predictionAdd
BLAST
Topological domaini395 – 43844Extracellular Reviewed predictionAdd
BLAST
Transmembranei439 – 45921Helical; Reviewed predictionAdd
BLAST
Topological domaini460 – 49536Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei496 – 51621Helical; Reviewed predictionAdd
BLAST
Topological domaini517 – 5182Extracellular Reviewed prediction
Transmembranei519 – 53921Helical; Reviewed predictionAdd
BLAST
Topological domaini540 – 57637Cytoplasmic Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. fungal-type vacuole Source: SGD
  2. integral component of membrane Source: SGD
  3. plasma membrane Source: SGD
  4. vacuolar membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane, Vacuole

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 576576Boron transporter 1PRO_0000079243Add
BLAST

Proteomic databases

MaxQBiP53838.
PaxDbiP53838.

Expressioni

Gene expression databases

GenevestigatoriP53838.

Interactioni

Protein-protein interaction databases

BioGridi35565. 20 interactions.
DIPiDIP-8001N.
STRINGi4932.YNL275W.

Structurei

3D structure databases

ProteinModelPortaliP53838.
SMRiP53838. Positions 69-110.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG268067.
GeneTreeiENSGT00560000076933.
HOGENOMiHOG000197283.
OMAiHWDIWLL.
OrthoDBiEOG7DRJBV.

Family and domain databases

InterProiIPR011531. HCO3_transpt_C.
IPR003020. HCO3_transpt_euk.
[Graphical view]
PANTHERiPTHR11453. PTHR11453. 1 hit.
PfamiPF00955. HCO3_cotransp. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P53838-1 [UniParc]FASTAAdd to Basket

« Hide

MSNESTRVTV SRGCTASDEC AQALERTNDE LDRESSVSES RSDEESHEKL    50
SRRRFPTLGI GIWLDLKDRI PYYKSDWVDA FNYRVIPSIV DTYFNNLLPA 100
IAFAQDMFDR TDNSYGVNEV LLSSAMAGIV FGVLGGQPLC IVGVTGPISI 150
FNYTVYEIIK PLNTSYFGFM FWICMWSMIF HLVLAFTNAV CLLQYVTTFP 200
CDIFGLFINV VYIQKGIQIL TRQFSAKSGE KSVQDGFASV VVALVMTAFG 250
LFFKLFHYYP LFSHRIRTFI SDYSTALSVL FWSSFTHFGG YLHDVKFKKL 300
PITKAFFPTS KVNRPQNTWL AYEPIPVKDV FIALPFGIFL TILFYFDHNV 350
SSLMAQRHQY KLKKPSSFHY DFALLGLTTC ISGVLGIPAP NGLIPQAPLH 400
TETLLVRDSN QKVISCVEQR FTNTFQGLMI LGTMTRPLLV CLGEIPQAVL 450
SGLFFIMGIN GLMTNSIIQR LVFLFSDPNR RDNTSPLMKV SKKSMLIFLS 500
FSLTGFAGEF AITNTIAAIG FPLVLLLSVL VSFSFAYIFP TEELKILDTN 550
VAQKFTIKNL LLENIRDAKF CDKHED 576
Length:576
Mass (Da):65,028
Last modified:October 1, 1996 - v1
Checksum:i4EA3FFC89F66307A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z71551 Genomic DNA. Translation: CAA96183.1.
BK006947 Genomic DNA. Translation: DAA10285.1.
PIRiS63249.
RefSeqiNP_014124.1. NM_001183113.1.

Genome annotation databases

EnsemblFungiiYNL275W; YNL275W; YNL275W.
GeneIDi855446.
KEGGisce:YNL275W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z71551 Genomic DNA. Translation: CAA96183.1 .
BK006947 Genomic DNA. Translation: DAA10285.1 .
PIRi S63249.
RefSeqi NP_014124.1. NM_001183113.1.

3D structure databases

ProteinModelPortali P53838.
SMRi P53838. Positions 69-110.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 35565. 20 interactions.
DIPi DIP-8001N.
STRINGi 4932.YNL275W.

Protein family/group databases

TCDBi 2.A.31.3.2. the anion exchanger (ae) family.

Proteomic databases

MaxQBi P53838.
PaxDbi P53838.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YNL275W ; YNL275W ; YNL275W .
GeneIDi 855446.
KEGGi sce:YNL275W.

Organism-specific databases

CYGDi YNL275w.
SGDi S000005219. BOR1.

Phylogenomic databases

eggNOGi NOG268067.
GeneTreei ENSGT00560000076933.
HOGENOMi HOG000197283.
OMAi HWDIWLL.
OrthoDBi EOG7DRJBV.

Enzyme and pathway databases

BioCyci YEAST:G3O-33269-MONOMER.

Miscellaneous databases

NextBioi 979346.

Gene expression databases

Genevestigatori P53838.

Family and domain databases

InterProi IPR011531. HCO3_transpt_C.
IPR003020. HCO3_transpt_euk.
[Graphical view ]
PANTHERi PTHR11453. PTHR11453. 1 hit.
Pfami PF00955. HCO3_cotransp. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications."
    Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J.
    , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.
    Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. "Expression and characterization of the anion transporter homologue YNL275w in Saccharomyces cerevisiae."
    Zhao R., Reithmeier R.A.F.
    Am. J. Physiol. 281:C33-C45(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION, TOPOLOGY.
  4. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  5. "Roles of BOR1, DUR3, and FPS1 in boron transport and tolerance in Saccharomyces cerevisiae."
    Nozawa A., Takano J., Kobayashi M., von Wiren N., Fujiwara T.
    FEMS Microbiol. Lett. 262:216-222(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  6. "Enolase activates homotypic vacuole fusion and protein transport to the vacuole in yeast."
    Decker B.L., Wickner W.T.
    J. Biol. Chem. 281:14523-14528(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION.
  7. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
    Kim H., Melen K., Oesterberg M., von Heijne G.
    Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: ATCC 208353 / W303-1A.
  8. "Transport and regulatory characteristics of the yeast bicarbonate transporter homolog Bor1p."
    Jennings M.L., Howren T.R., Cui J., Winters M., Hannigan R.
    Am. J. Physiol. 293:C468-C476(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  9. "Saccharomyces cerevisiae Bor1p is a boron exporter and a key determinant of boron tolerance."
    Takano J., Kobayashi M., Noda Y., Fujiwara T.
    FEMS Microbiol. Lett. 267:230-235(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION.

Entry informationi

Entry nameiBOR1_YEAST
AccessioniPrimary (citable) accession number: P53838
Secondary accession number(s): D6W0R9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 14, 2014
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 195 molecules/cell in log phase SD medium.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XIV
    Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

External Data

Dasty 3

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