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P53824 (SNZ2_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 102. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable pyridoxine biosynthesis protein SNZ2
Alternative name(s):
PDX1 homolog 2
Gene names
Name:SNZ2
Ordered Locus Names:YNL333W
ORF Names:N0290
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length298 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

May be required for the production of pyridoxine (vitamin B6). Ref.4

Subunit structure

Interacts with THI11. Ref.4

Induction

By the absence of external thiamine. Ref.4

Sequence similarities

Belongs to the PdxS/SNZ family.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

SNO1Q031443EBI-17623,EBI-28190

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 298298Probable pyridoxine biosynthesis protein SNZ2 HAMAP-Rule MF_01824
PRO_0000109359

Sequences

Sequence LengthMass (Da)Tools
P53824 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: EE02E7C546C460AC

FASTA29832,033
        10         20         30         40         50         60 
MSEFKVKTGL AQMLKGGVIM DVVTPEQAII AERAGACAVM ALERIPADMR KSGQVCRMSD 

        70         80         90        100        110        120 
PRMIKEIMEA VSIPVMAKVR IGHFVEAQIL EELQVDYIDE SEVLTPADWT HHIEKHNFKV 

       130        140        150        160        170        180 
PFVCGAKDLG EALRRINEGA AMIRTKGEAG TGDVSEAVKH ITKIKAEIQQ YKENLKTESD 

       190        200        210        220        230        240 
FAAKATELRV PVDLLKTTLS EGKLPVVNFA AGGVATPADA ALLMQLGCEG VFVGSGIFKS 

       250        260        270        280        290 
SDPEKLACAI VEATTHYDNP AKLLQISSDL GDLMGGISIQ SINEAGGKNG ARLSEIGW 

« Hide

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications."
Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J. expand/collapse author list , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.
Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[3]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[4]"Functional analysis of yeast gene families involved in metabolism of vitamins B1 and B6."
Rodriguez-Navarro S., Llorente B., Rodriguez-Manzaneque M.T., Ramne A., Uber G., Marchesan D., Dujon B., Herrero E., Sunnerhagen P., Perez-Ortin J.E.
Yeast 19:1261-1276(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: PROBABLE FUNCTION, INDUCTION, INTERACTION WITH THI11.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z71608 Genomic DNA. Translation: CAA96266.1.
Z71609 Genomic DNA. Translation: CAA96267.1.
AY692873 Genomic DNA. Translation: AAT92892.1.
BK006947 Genomic DNA. Translation: DAA10230.1.
RefSeqNP_014066.1. NM_001183171.1.

3D structure databases

ProteinModelPortalP53824.
SMRP53824. Positions 14-271.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid35508. 12 interactions.
DIPDIP-1695N.
IntActP53824. 12 interactions.
MINTMINT-406912.
STRING4932.YNL333W.

Proteomic databases

PaxDbP53824.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYNL333W; YNL333W; YNL333W.
GeneID855383.
KEGGsce:YNL333W.

Organism-specific databases

CYGDYNL333w.
SGDS000005277. SNZ2.

Phylogenomic databases

eggNOGCOG0214.
GeneTreeENSGT00390000018460.
HOGENOMHOG000227586.
OMAADEECHI.
OrthoDBEOG7TN031.

Enzyme and pathway databases

BioCycYEAST:G3O-33316-MONOMER.

Gene expression databases

GenevestigatorP53824.

Family and domain databases

Gene3D3.20.20.70. 2 hits.
HAMAPMF_01824. PdxS.
InterProIPR013785. Aldolase_TIM.
IPR011060. RibuloseP-bd_barrel.
IPR001852. Snz1p/Sor1.
[Graphical view]
PfamPF01680. SOR_SNZ. 1 hit.
[Graphical view]
PIRSFPIRSF029271. Pdx1. 1 hit.
SUPFAMSSF51366. SSF51366. 1 hit.
TIGRFAMsTIGR00343. TIGR00343. 1 hit.
PROSITEPS01235. PDXS_SNZ_1. 1 hit.
PS51129. PDXS_SNZ_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio979178.

Entry information

Entry nameSNZ2_YEAST
AccessionPrimary (citable) accession number: P53824
Secondary accession number(s): D6W0L4
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: February 19, 2014
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XIV

Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families