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P53824

- SNZ2_YEAST

UniProt

P53824 - SNZ2_YEAST

Protein

Probable pyridoxine biosynthesis protein SNZ2

Gene

SNZ2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 105 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
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    Functioni

    May be required for the production of pyridoxine (vitamin B6).

    GO - Molecular functioni

    1. GMP synthase (glutamine-hydrolyzing) activity Source: SGD
    2. protein binding Source: IntAct

    GO - Biological processi

    1. pyridoxal phosphate biosynthetic process Source: InterPro
    2. pyridoxine biosynthetic process Source: SGD

    Keywords - Biological processi

    Pyridoxine biosynthesis

    Enzyme and pathway databases

    BioCyciYEAST:G3O-33316-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable pyridoxine biosynthesis protein SNZ2
    Alternative name(s):
    PDX1 homolog 2
    Gene namesi
    Name:SNZ2
    Ordered Locus Names:YNL333W
    ORF Names:N0290
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome XIV

    Organism-specific databases

    CYGDiYNL333w.
    SGDiS000005277. SNZ2.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 298298Probable pyridoxine biosynthesis protein SNZ2PRO_0000109359Add
    BLAST

    Proteomic databases

    MaxQBiP53824.
    PaxDbiP53824.

    Expressioni

    Inductioni

    By the absence of external thiamine.1 Publication

    Gene expression databases

    GenevestigatoriP53824.

    Interactioni

    Subunit structurei

    Interacts with THI11.1 Publication

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    SNO1Q031443EBI-17623,EBI-28190

    Protein-protein interaction databases

    BioGridi35508. 12 interactions.
    DIPiDIP-1695N.
    IntActiP53824. 12 interactions.
    MINTiMINT-406912.
    STRINGi4932.YNL333W.

    Structurei

    3D structure databases

    ProteinModelPortaliP53824.
    SMRiP53824. Positions 14-271.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PdxS/SNZ family.Curated

    Phylogenomic databases

    eggNOGiCOG0214.
    GeneTreeiENSGT00390000018460.
    HOGENOMiHOG000227586.
    OMAiPRDLPAC.
    OrthoDBiEOG7TN031.

    Family and domain databases

    Gene3Di3.20.20.70. 2 hits.
    HAMAPiMF_01824. PdxS.
    InterProiIPR013785. Aldolase_TIM.
    IPR011060. RibuloseP-bd_barrel.
    IPR001852. Snz1p/Sor1.
    [Graphical view]
    PfamiPF01680. SOR_SNZ. 1 hit.
    [Graphical view]
    PIRSFiPIRSF029271. Pdx1. 1 hit.
    SUPFAMiSSF51366. SSF51366. 1 hit.
    TIGRFAMsiTIGR00343. TIGR00343. 1 hit.
    PROSITEiPS01235. PDXS_SNZ_1. 1 hit.
    PS51129. PDXS_SNZ_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P53824-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSEFKVKTGL AQMLKGGVIM DVVTPEQAII AERAGACAVM ALERIPADMR    50
    KSGQVCRMSD PRMIKEIMEA VSIPVMAKVR IGHFVEAQIL EELQVDYIDE 100
    SEVLTPADWT HHIEKHNFKV PFVCGAKDLG EALRRINEGA AMIRTKGEAG 150
    TGDVSEAVKH ITKIKAEIQQ YKENLKTESD FAAKATELRV PVDLLKTTLS 200
    EGKLPVVNFA AGGVATPADA ALLMQLGCEG VFVGSGIFKS SDPEKLACAI 250
    VEATTHYDNP AKLLQISSDL GDLMGGISIQ SINEAGGKNG ARLSEIGW 298
    Length:298
    Mass (Da):32,033
    Last modified:October 1, 1996 - v1
    Checksum:iEE02E7C546C460AC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z71608 Genomic DNA. Translation: CAA96266.1.
    Z71609 Genomic DNA. Translation: CAA96267.1.
    AY692873 Genomic DNA. Translation: AAT92892.1.
    BK006947 Genomic DNA. Translation: DAA10230.1.
    RefSeqiNP_014066.1. NM_001183171.1.

    Genome annotation databases

    EnsemblFungiiYNL333W; YNL333W; YNL333W.
    GeneIDi855383.
    KEGGisce:YNL333W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z71608 Genomic DNA. Translation: CAA96266.1 .
    Z71609 Genomic DNA. Translation: CAA96267.1 .
    AY692873 Genomic DNA. Translation: AAT92892.1 .
    BK006947 Genomic DNA. Translation: DAA10230.1 .
    RefSeqi NP_014066.1. NM_001183171.1.

    3D structure databases

    ProteinModelPortali P53824.
    SMRi P53824. Positions 14-271.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 35508. 12 interactions.
    DIPi DIP-1695N.
    IntActi P53824. 12 interactions.
    MINTi MINT-406912.
    STRINGi 4932.YNL333W.

    Proteomic databases

    MaxQBi P53824.
    PaxDbi P53824.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YNL333W ; YNL333W ; YNL333W .
    GeneIDi 855383.
    KEGGi sce:YNL333W.

    Organism-specific databases

    CYGDi YNL333w.
    SGDi S000005277. SNZ2.

    Phylogenomic databases

    eggNOGi COG0214.
    GeneTreei ENSGT00390000018460.
    HOGENOMi HOG000227586.
    OMAi PRDLPAC.
    OrthoDBi EOG7TN031.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-33316-MONOMER.

    Miscellaneous databases

    NextBioi 979178.

    Gene expression databases

    Genevestigatori P53824.

    Family and domain databases

    Gene3Di 3.20.20.70. 2 hits.
    HAMAPi MF_01824. PdxS.
    InterProi IPR013785. Aldolase_TIM.
    IPR011060. RibuloseP-bd_barrel.
    IPR001852. Snz1p/Sor1.
    [Graphical view ]
    Pfami PF01680. SOR_SNZ. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF029271. Pdx1. 1 hit.
    SUPFAMi SSF51366. SSF51366. 1 hit.
    TIGRFAMsi TIGR00343. TIGR00343. 1 hit.
    PROSITEi PS01235. PDXS_SNZ_1. 1 hit.
    PS51129. PDXS_SNZ_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications."
      Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J.
      , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.
      Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. Cited for: PROBABLE FUNCTION, INDUCTION, INTERACTION WITH THI11.

    Entry informationi

    Entry nameiSNZ2_YEAST
    AccessioniPrimary (citable) accession number: P53824
    Secondary accession number(s): D6W0L4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 105 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome XIV
      Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

    External Data

    Dasty 3