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P53824

- SNZ2_YEAST

UniProt

P53824 - SNZ2_YEAST

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Protein

Probable pyridoxine biosynthesis protein SNZ2

Gene
SNZ2, YNL333W, N0290
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

May be required for the production of pyridoxine (vitamin B6).1 Publication

GO - Molecular functioni

  1. GMP synthase (glutamine-hydrolyzing) activity Source: SGD
  2. protein binding Source: IntAct

GO - Biological processi

  1. pyridoxal phosphate biosynthetic process Source: InterPro
  2. pyridoxine biosynthetic process Source: SGD
Complete GO annotation...

Keywords - Biological processi

Pyridoxine biosynthesis

Enzyme and pathway databases

BioCyciYEAST:G3O-33316-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable pyridoxine biosynthesis protein SNZ2
Alternative name(s):
PDX1 homolog 2
Gene namesi
Name:SNZ2
Ordered Locus Names:YNL333W
ORF Names:N0290
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome XIV

Organism-specific databases

CYGDiYNL333w.
SGDiS000005277. SNZ2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 298298Probable pyridoxine biosynthesis protein SNZ2UniRule annotationPRO_0000109359Add
BLAST

Proteomic databases

MaxQBiP53824.
PaxDbiP53824.

Expressioni

Inductioni

By the absence of external thiamine.1 Publication

Gene expression databases

GenevestigatoriP53824.

Interactioni

Subunit structurei

Interacts with THI11.1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
SNO1Q031443EBI-17623,EBI-28190

Protein-protein interaction databases

BioGridi35508. 12 interactions.
DIPiDIP-1695N.
IntActiP53824. 12 interactions.
MINTiMINT-406912.
STRINGi4932.YNL333W.

Structurei

3D structure databases

ProteinModelPortaliP53824.
SMRiP53824. Positions 14-271.

Family & Domainsi

Sequence similaritiesi

Belongs to the PdxS/SNZ family.

Phylogenomic databases

eggNOGiCOG0214.
GeneTreeiENSGT00390000018460.
HOGENOMiHOG000227586.
OMAiPRDLPAC.
OrthoDBiEOG7TN031.

Family and domain databases

Gene3Di3.20.20.70. 2 hits.
HAMAPiMF_01824. PdxS.
InterProiIPR013785. Aldolase_TIM.
IPR011060. RibuloseP-bd_barrel.
IPR001852. Snz1p/Sor1.
[Graphical view]
PfamiPF01680. SOR_SNZ. 1 hit.
[Graphical view]
PIRSFiPIRSF029271. Pdx1. 1 hit.
SUPFAMiSSF51366. SSF51366. 1 hit.
TIGRFAMsiTIGR00343. TIGR00343. 1 hit.
PROSITEiPS01235. PDXS_SNZ_1. 1 hit.
PS51129. PDXS_SNZ_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P53824-1 [UniParc]FASTAAdd to Basket

« Hide

MSEFKVKTGL AQMLKGGVIM DVVTPEQAII AERAGACAVM ALERIPADMR    50
KSGQVCRMSD PRMIKEIMEA VSIPVMAKVR IGHFVEAQIL EELQVDYIDE 100
SEVLTPADWT HHIEKHNFKV PFVCGAKDLG EALRRINEGA AMIRTKGEAG 150
TGDVSEAVKH ITKIKAEIQQ YKENLKTESD FAAKATELRV PVDLLKTTLS 200
EGKLPVVNFA AGGVATPADA ALLMQLGCEG VFVGSGIFKS SDPEKLACAI 250
VEATTHYDNP AKLLQISSDL GDLMGGISIQ SINEAGGKNG ARLSEIGW 298
Length:298
Mass (Da):32,033
Last modified:October 1, 1996 - v1
Checksum:iEE02E7C546C460AC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z71608 Genomic DNA. Translation: CAA96266.1.
Z71609 Genomic DNA. Translation: CAA96267.1.
AY692873 Genomic DNA. Translation: AAT92892.1.
BK006947 Genomic DNA. Translation: DAA10230.1.
RefSeqiNP_014066.1. NM_001183171.1.

Genome annotation databases

EnsemblFungiiYNL333W; YNL333W; YNL333W.
GeneIDi855383.
KEGGisce:YNL333W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z71608 Genomic DNA. Translation: CAA96266.1 .
Z71609 Genomic DNA. Translation: CAA96267.1 .
AY692873 Genomic DNA. Translation: AAT92892.1 .
BK006947 Genomic DNA. Translation: DAA10230.1 .
RefSeqi NP_014066.1. NM_001183171.1.

3D structure databases

ProteinModelPortali P53824.
SMRi P53824. Positions 14-271.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 35508. 12 interactions.
DIPi DIP-1695N.
IntActi P53824. 12 interactions.
MINTi MINT-406912.
STRINGi 4932.YNL333W.

Proteomic databases

MaxQBi P53824.
PaxDbi P53824.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YNL333W ; YNL333W ; YNL333W .
GeneIDi 855383.
KEGGi sce:YNL333W.

Organism-specific databases

CYGDi YNL333w.
SGDi S000005277. SNZ2.

Phylogenomic databases

eggNOGi COG0214.
GeneTreei ENSGT00390000018460.
HOGENOMi HOG000227586.
OMAi PRDLPAC.
OrthoDBi EOG7TN031.

Enzyme and pathway databases

BioCyci YEAST:G3O-33316-MONOMER.

Miscellaneous databases

NextBioi 979178.

Gene expression databases

Genevestigatori P53824.

Family and domain databases

Gene3Di 3.20.20.70. 2 hits.
HAMAPi MF_01824. PdxS.
InterProi IPR013785. Aldolase_TIM.
IPR011060. RibuloseP-bd_barrel.
IPR001852. Snz1p/Sor1.
[Graphical view ]
Pfami PF01680. SOR_SNZ. 1 hit.
[Graphical view ]
PIRSFi PIRSF029271. Pdx1. 1 hit.
SUPFAMi SSF51366. SSF51366. 1 hit.
TIGRFAMsi TIGR00343. TIGR00343. 1 hit.
PROSITEi PS01235. PDXS_SNZ_1. 1 hit.
PS51129. PDXS_SNZ_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications."
    Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J.
    , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.
    Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. Cited for: PROBABLE FUNCTION, INDUCTION, INTERACTION WITH THI11.

Entry informationi

Entry nameiSNZ2_YEAST
AccessioniPrimary (citable) accession number: P53824
Secondary accession number(s): D6W0L4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: June 11, 2014
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XIV
    Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

External Data

Dasty 3

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