P53752 (YN95_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized membrane glycoprotein YNR066C

Gene names

Ordered Locus Names:	YNR066C
ORF Names:	N3543

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	436 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Subcellular location	Membrane; Single-pass membrane protein Potential.
Sequence similarities	Contains 4 BNR repeats.

Ontologies

Keywords
Cellular component	Membrane
Domain	Repeat Transmembrane Transmembrane helix
PTM	Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from sequence model PubMed 12192589. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 436	436	Uncharacterized membrane glycoprotein YNR066C		PRO_0000203484
Regions
	Transmembrane	1 – 21	21	Helical; Potential
	Repeat	57 – 68	12	BNR 1
	Repeat	101 – 112	12	BNR 2
	Repeat	229 – 240	12	BNR 3
	Repeat	394 – 405	12	BNR 4
Amino acid modifications
	Glycosylation	157	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	P53752 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 37002190F68E35E8	FASTA	436	49,655
	10 20 30 40 50 60 MILLQVICTI WTCLFIPLLN AEEFVPKVTE TLSEYSFSLE SFDDSNSLIR LDNQVVWISS 70 80 90 100 110 120 DSGENWEAVK EIEGHILELI VDPLHGQDRA FVSIHLSPKF YVTDDRGKSW RALTIPVSEN 130 140 150 160 170 180 CRLGTSCSIA THPTDKKYLI ADCPCFINDN GYIQIQNETY FTNDGESFYN IEPSLKKKED 190 200 210 220 230 240 DHITSSSCNF VKSSKDSDIE GNDASILCLF SNHGYDSDRH LSAAYTQLAL STDGGKTFKK 250 260 270 280 290 300 FDEFNDKIIY QYKILKSHII VSTQDDRYNE MSPMDIWISN DASTFQKARL PAQVRHVHMY 310 320 330 340 350 360 GIYEDSIGRI IIPISTIFTD EKNDQPAPSE ILISDSQGLK FLPVEWTINP HFGYIDIASP 370 380 390 400 410 420 HFLEGTIIGS FHPSFDYSHN KGKYNKKIAR YETKISVDNG LTWSNLKVVD EENADSFPCD 430 ITRPERCSLQ NPFYSI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications." Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J. , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J. Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z71681 Genomic DNA. Translation: CAA96348.1. BK006947 Genomic DNA. Translation: DAA10607.1.
PIR	S63398.
RefSeq	NP_014464.3. NM_001183243.3.
3D structure databases
ProteinModelPortal	P53752.
SMR	P53752. Positions 44-114, 200-242, 274-343, 354-407.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-4562N.
MINT	MINT-557159.
STRING	4932.YNR066C.
Proteomic databases
PaxDb	P53752.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YNR066C; YNR066C; YNR066C.
GeneID	855803.
KEGG	sce:YNR066C. sce:YNR073C.
Organism-specific databases
CYGD	YNR066c.
SGD	S000005349. YNR066C.
Phylogenomic databases
eggNOG	NOG281049.
GeneTree	ENSGT00510000046443.
KO	K00045.
OrthoDB	EOG46T68P.
Gene expression databases
Genevestigator	P53752.
GermOnline	YNR066C. Saccharomyces cerevisiae.
Family and domain databases
ProtoNet	Search...
Other
NextBio	980315.

Entry information

Entry name

YN95_YEAST

Accession

Primary (citable) accession number: P53752
Secondary accession number(s): D6W1P1

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	May 1, 2013
This is version 87 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program