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Protein

Probable alpha-1,3-mannosyltransferase MNT4

Gene

MNT4

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

  • alpha-1,3-mannosyltransferase activity Source: SGD

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase

Enzyme and pathway databases

BioCyciYEAST:G3O-33363-MONOMER

Protein family/group databases

CAZyiGT71 Glycosyltransferase Family 71

Names & Taxonomyi

Protein namesi
Recommended name:
Probable alpha-1,3-mannosyltransferase MNT4 (EC:2.4.1.-)
Gene namesi
Name:MNT4
Ordered Locus Names:YNR059W
ORF Names:N3514
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIV

Organism-specific databases

EuPathDBiFungiDB:YNR059W
SGDiS000005342 MNT4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 10CytoplasmicSequence analysis10
Transmembranei11 – 29Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST19
Topological domaini30 – 580LumenalSequence analysisAdd BLAST551

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000805611 – 580Probable alpha-1,3-mannosyltransferase MNT4Add BLAST580

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi132N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi167N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi223N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi349N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiP53745
PaxDbiP53745
PRIDEiP53745

Interactioni

Protein-protein interaction databases

BioGridi35885, 41 interactors
DIPiDIP-5262N
IntActiP53745, 2 interactors
MINTiP53745
STRINGi4932.YNR059W

Structurei

3D structure databases

ProteinModelPortaliP53745
SMRiP53745
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MNN1/MNT family.Curated

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00390000003622
HOGENOMiHOG000113620
InParanoidiP53745
OrthoDBiEOG092C553O

Family and domain databases

InterProiView protein in InterPro
IPR022751 Alpha_mannosyltransferase
IPR029044 Nucleotide-diphossugar_trans
PfamiView protein in Pfam
PF11051 Mannosyl_trans3, 1 hit
SUPFAMiSSF53448 SSF53448, 2 hits

Sequencei

Sequence statusi: Complete.

P53745-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLRIRRIKK LAPLIFTSLL SLIVLFRVYR QYPFSDHFET RREDDRSGNV
60 70 80 90 100
HCFSRLRQIE EYEKPELTSK FYEPNRWKSF ISYVTRSRKD VKTVSRSLSN
110 120 130 140 150
LDLYQKCSKE IRADQDISLL HSIETKLFPY INFTALNSEQ SHNFWPVHTR
160 170 180 190 200
FDGTKYRGQV LQFSSENNSF IGTSPIEFKA SEPFWENWLN SALQRNSKGV
210 220 230 240 250
VMSVSEYLVA DTIRLIRVLR LLNNSLPIEI VHKSDLHESS QQLLIAAARE
260 270 280 290 300
SGSLNYPPQE LWFLDVKDML NDEYLARFKR FSNKWLAITF CSFQIPIFLD
310 320 330 340 350
SDTVPFVPLD TLYEIDGFKR TGTLFFKDRS FPTSKLSPLQ VKVLKQIINN
360 370 380 390 400
SLDVSSDSEQ GFEILKHNLN DEMAIDAIEA LIFKKQKHYM DSGLVIFDKQ
410 420 430 440 450
KHFFCLPIAI MLQFSPIQEF FHGDKEWFWL SLFISKKEFT FYPIEASNVG
460 470 480 490 500
RLEKPETLES STICSTQLSH TDVYGNLLWL NGGLSVCKKN CWNYDFTKRK
510 520 530 540 550
EIAAKYKSVD ELRNYYQSPV KLEAVIIPDV SKSPWSQQSE CVMYSYCTHY
560 570 580
RKGQYGKLIE FTDSQKKYYE KVVELWNKVV
Length:580
Mass (Da):68,082
Last modified:October 1, 1996 - v1
Checksum:iF94C53283887EC62
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti50V → L in AAB63969 (PubMed:10333520).Curated1
Sequence conflicti87S → G in AAB63969 (PubMed:10333520).Curated1
Sequence conflicti134T → A in AAB63969 (PubMed:10333520).Curated1
Sequence conflicti206E → D in AAB63969 (PubMed:10333520).Curated1
Sequence conflicti254 – 267LNYPP…FLDVK → PGTELELRPQFTG in AAB63969 (PubMed:10333520).CuratedAdd BLAST14

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z71674 Genomic DNA Translation: CAA96341.1
U53467 Genomic DNA Translation: AAB63969.1
BK006947 Genomic DNA Translation: DAA10600.1
PIRiS63391
RefSeqiNP_014457.3, NM_001183236.3

Genome annotation databases

EnsemblFungiiYNR059W; YNR059W; YNR059W
GeneIDi855796
KEGGisce:YNR059W

Similar proteinsi

Entry informationi

Entry nameiMNT4_YEAST
AccessioniPrimary (citable) accession number: P53745
Secondary accession number(s): D6W1N4, Q03127
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 23, 2018
This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XIV
    Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

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