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Protein

37S ribosomal protein S19, mitochondrial

Gene

RSM19

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.2 Publications

GO - Molecular functioni

  • RNA binding Source: InterPro
  • structural constituent of ribosome Source: SGD

GO - Biological processi

  • mitochondrial translation Source: SGD
  • ribosomal small subunit assembly Source: GO_Central

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-33347-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
37S ribosomal protein S19, mitochondrial
Alternative name(s):
Mitochondrial small ribosomal subunit protein uS19m1 Publication
Gene namesi
Name:RSM19
Ordered Locus Names:YNR037C
ORF Names:N3300
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIV

Organism-specific databases

EuPathDBiFungiDB:YNR037C
SGDiS000005320 RSM19

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001300251 – 9137S ribosomal protein S19, mitochondrialAdd BLAST91

Proteomic databases

MaxQBiP53733
PaxDbiP53733
PRIDEiP53733

Interactioni

Subunit structurei

Component of the mitochondrial small ribosomal subunit (mt-SSU). Mature yeast 74S mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S small subunit contains a 15S ribosomal RNA (15S mt-rRNA) and 34 different proteins. The 54S large subunit contains a 21S rRNA (21S mt-rRNA) and 46 different proteins.3 Publications

Protein-protein interaction databases

BioGridi35863, 184 interactors
DIPiDIP-4257N
IntActiP53733, 5 interactors
MINTiP53733
STRINGi4932.YNR037C

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5MRCelectron microscopy3.25SS9-88[»]
5MREelectron microscopy3.75SS9-88[»]
5MRFelectron microscopy4.97SS9-88[»]
ProteinModelPortaliP53733
SMRiP53733
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000111560
InParanoidiP53733
OMAiGLKFQVH
OrthoDBiEOG092C5LSV

Family and domain databases

Gene3Di3.30.860.10, 1 hit
HAMAPiMF_00531 Ribosomal_S19, 1 hit
InterProiView protein in InterPro
IPR002222 Ribosomal_S19
IPR020934 Ribosomal_S19_CS
IPR023575 Ribosomal_S19_SF
PANTHERiPTHR11880 PTHR11880, 1 hit
PfamiView protein in Pfam
PF00203 Ribosomal_S19, 1 hit
PIRSFiPIRSF002144 Ribosomal_S19, 1 hit
PRINTSiPR00975 RIBOSOMALS19
SUPFAMiSSF54570 SSF54570, 1 hit
PROSITEiView protein in PROSITE
PS00323 RIBOSOMAL_S19, 1 hit

Sequencei

Sequence statusi: Complete.

P53733-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQPAARLLSR SVWKGPNIVP LPIREAMTKG TPIRTNARAA TILPQFVGLK
60 70 80 90
FQIHNGKEYV PIEISEDMVG HKLGEFAPTR KRFSYTQTKN K
Length:91
Mass (Da):10,275
Last modified:October 1, 1996 - v1
Checksum:iB39624808BDD9092
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z71652 Genomic DNA Translation: CAA96317.1
BK006947 Genomic DNA Translation: DAA10579.1
PIRiS63368
RefSeqiNP_014435.3, NM_001183214.3

Genome annotation databases

EnsemblFungiiYNR037C; YNR037C; YNR037C
GeneIDi855773
KEGGisce:YNR037C

Similar proteinsi

Entry informationi

Entry nameiRT19_YEAST
AccessioniPrimary (citable) accession number: P53733
Secondary accession number(s): D6W1L3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 23, 2018
This is version 141 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

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