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P53724

- RM50_YEAST

UniProt

P53724 - RM50_YEAST

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Protein

54S ribosomal protein L50, mitochondrial

Gene
MRPL50, YNR022C, N3220
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. structural constituent of ribosome Source: SGD

GO - Biological processi

  1. mitochondrial translation Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-33336-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
54S ribosomal protein L50, mitochondrial
Gene namesi
Name:MRPL50
Ordered Locus Names:YNR022C
ORF Names:N3220
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome XIV

Organism-specific databases

CYGDiYNR022c.
SGDiS000005305. MRPL50.

Subcellular locationi

Mitochondrion 2 Publications

GO - Cellular componenti

  1. mitochondrial large ribosomal subunit Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 13913954S ribosomal protein L50, mitochondrialPRO_0000030584Add
BLAST

Proteomic databases

MaxQBiP53724.
PaxDbiP53724.

Expressioni

Gene expression databases

GenevestigatoriP53724.

Interactioni

Subunit structurei

Component of the mitochondrial large ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S).1 Publication

Protein-protein interaction databases

BioGridi35847. 46 interactions.
DIPiDIP-1265N.
IntActiP53724. 4 interactions.
MINTiMINT-402743.
STRINGi4932.YNR022C.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1VW4electron microscopy3.20G1-139[»]
ProteinModelPortaliP53724.
SMRiP53724. Positions 19-62.

Family & Domainsi

Phylogenomic databases

eggNOGiNOG43083.
HOGENOMiHOG000057082.
OMAiKARIIRF.
OrthoDBiEOG7QZGQD.

Sequencei

Sequence statusi: Complete.

P53724-1 [UniParc]FASTAAdd to Basket

« Hide

MLHCTQVCLS ALTKRTHRVK VQVLKDFPRF QLYKGQVANV KPSLMRNYLH    50
NFNGAKYILS EEHDINTELL KQYQTLEAKL EEDHQQLSKR HETEVQKNME 100
LRKESVFGHK KEEKPKEEKK GLLDSGITIE EVKIPGLDI 139
Length:139
Mass (Da):16,283
Last modified:October 1, 1996 - v1
Checksum:i9B03AA8C283063E9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z71637 Genomic DNA. Translation: CAA96301.1.
BK006947 Genomic DNA. Translation: DAA10563.1.
PIRiS63353.
RefSeqiNP_014419.1. NM_001183199.1.

Genome annotation databases

EnsemblFungiiYNR022C; YNR022C; YNR022C.
GeneIDi855756.
KEGGisce:YNR022C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z71637 Genomic DNA. Translation: CAA96301.1 .
BK006947 Genomic DNA. Translation: DAA10563.1 .
PIRi S63353.
RefSeqi NP_014419.1. NM_001183199.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1VW4 electron microscopy 3.20 G 1-139 [» ]
ProteinModelPortali P53724.
SMRi P53724. Positions 19-62.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 35847. 46 interactions.
DIPi DIP-1265N.
IntActi P53724. 4 interactions.
MINTi MINT-402743.
STRINGi 4932.YNR022C.

Proteomic databases

MaxQBi P53724.
PaxDbi P53724.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YNR022C ; YNR022C ; YNR022C .
GeneIDi 855756.
KEGGi sce:YNR022C.

Organism-specific databases

CYGDi YNR022c.
SGDi S000005305. MRPL50.

Phylogenomic databases

eggNOGi NOG43083.
HOGENOMi HOG000057082.
OMAi KARIIRF.
OrthoDBi EOG7QZGQD.

Enzyme and pathway databases

BioCyci YEAST:G3O-33336-MONOMER.

Miscellaneous databases

NextBioi 980181.

Gene expression databases

Genevestigatori P53724.

Family and domain databases

ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications."
    Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J.
    , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.
    Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. "Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components."
    Gan X., Kitakawa M., Yoshino K., Oshiro N., Yonezawa K., Isono K.
    Eur. J. Biochem. 269:5203-5214(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION IN THE MITOCHONDRIAL RIBOSOMAL LARGE COMPLEX, IDENTIFICATION BY MASS SPECTROMETRY.
  4. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  5. "Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics."
    Reinders J., Zahedi R.P., Pfanner N., Meisinger C., Sickmann A.
    J. Proteome Res. 5:1543-1554(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiRM50_YEAST
AccessioniPrimary (citable) accession number: P53724
Secondary accession number(s): D6W1J7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: June 11, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XIV
    Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

External Data

Dasty 3

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