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P53703

- CCHL_CAEEL

UniProt

P53703 - CCHL_CAEEL

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Protein

Probable cytochrome c-type heme lyase

Gene

cchl-1

Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Links covalently the heme group to the apoprotein of cytochrome c.By similarity

Catalytic activityi

Holocytochrome c = apocytochrome c + heme.

GO - Molecular functioni

  1. holocytochrome-c synthase activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cytochrome c-type heme lyase (EC:4.4.1.17)
Short name:
CCHL
Alternative name(s):
Holocytochrome-c-type synthase
Gene namesi
Name:cchl-1
ORF Names:T06D8.6
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome II

Organism-specific databases

WormBaseiT06D8.6; CE02327; WBGene00011527; cchl-1.

Subcellular locationi

GO - Cellular componenti

  1. mitochondrial inner membrane Source: UniProtKB-KW
  2. mitochondrion Source: WormBase
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 280280Probable cytochrome c-type heme lyasePRO_0000121714Add
BLAST

Proteomic databases

PaxDbiP53703.

Interactioni

Protein-protein interaction databases

STRINGi6239.T06D8.6.2.

Structurei

3D structure databases

ProteinModelPortaliP53703.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati35 – 406HRM 1
Repeati56 – 616HRM 2

Sequence similaritiesi

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiNOG236101.
GeneTreeiENSGT00390000004175.
HOGENOMiHOG000170352.
InParanoidiP53703.
KOiK01764.
OMAiNNELEHP.
PhylomeDBiP53703.

Family and domain databases

InterProiIPR000511. Cyt_C/C1_haem_lyase.
[Graphical view]
PANTHERiPTHR12743. PTHR12743. 1 hit.
PfamiPF01265. Cyto_heme_lyase. 1 hit.
[Graphical view]
PROSITEiPS00821. CYTO_HEME_LYASE_1. 1 hit.
PS00822. CYTO_HEME_LYASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P53703-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGSSQSTPKV QDANADAERI RKAQHSMAAA GGGSQCPLTP EQRAAASGEN
60 70 80 90 100
CGAGGACPVG ADKASINPLN NELEHPNQKP APDQPFALPT KREKSTIPKA
110 120 130 140 150
GTETETWTYP SPQMFWNAML KKGWRWQDDS LSKSDMENII SIHNANNEEA
160 170 180 190 200
WREVLKWENL LHPECAEPKL KSFKGDAKNL SPRARFRNLF LGYDLPFDRH
210 220 230 240 250
DWIVDRCGTK QVQYVIDYYD GGAVDPSSKL FTILDVRPAV NDIGNIWDRM
260 270 280
VVAYWRFKFE TLGFTPSLPI PPTEGHNVNH
Length:280
Mass (Da):31,263
Last modified:October 1, 1996 - v1
Checksum:i8916E0315AA46724
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z49130 Genomic DNA. Translation: CAA88969.1.
PIRiT24579.
RefSeqiNP_496403.1. NM_064002.5.
UniGeneiCel.6562.

Genome annotation databases

EnsemblMetazoaiT06D8.6.1; T06D8.6.1; WBGene00011527.
T06D8.6.2; T06D8.6.2; WBGene00011527.
GeneIDi174713.
KEGGicel:CELE_T06D8.6.
UCSCiT06D8.6.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z49130 Genomic DNA. Translation: CAA88969.1 .
PIRi T24579.
RefSeqi NP_496403.1. NM_064002.5.
UniGenei Cel.6562.

3D structure databases

ProteinModelPortali P53703.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 6239.T06D8.6.2.

Proteomic databases

PaxDbi P53703.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai T06D8.6.1 ; T06D8.6.1 ; WBGene00011527 .
T06D8.6.2 ; T06D8.6.2 ; WBGene00011527 .
GeneIDi 174713.
KEGGi cel:CELE_T06D8.6.
UCSCi T06D8.6.1. c. elegans.

Organism-specific databases

CTDi 174713.
WormBasei T06D8.6 ; CE02327 ; WBGene00011527 ; cchl-1.

Phylogenomic databases

eggNOGi NOG236101.
GeneTreei ENSGT00390000004175.
HOGENOMi HOG000170352.
InParanoidi P53703.
KOi K01764.
OMAi NNELEHP.
PhylomeDBi P53703.

Miscellaneous databases

NextBioi 885180.
PROi P53703.

Family and domain databases

InterProi IPR000511. Cyt_C/C1_haem_lyase.
[Graphical view ]
PANTHERi PTHR12743. PTHR12743. 1 hit.
Pfami PF01265. Cyto_heme_lyase. 1 hit.
[Graphical view ]
PROSITEi PS00821. CYTO_HEME_LYASE_1. 1 hit.
PS00822. CYTO_HEME_LYASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiCCHL_CAEEL
AccessioniPrimary (citable) accession number: P53703
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: October 29, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3