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P53703

- CCHL_CAEEL

UniProt

P53703 - CCHL_CAEEL

Protein

Probable cytochrome c-type heme lyase

Gene

cchl-1

Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 89 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
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    Functioni

    Links covalently the heme group to the apoprotein of cytochrome c.By similarity

    Catalytic activityi

    Holocytochrome c = apocytochrome c + heme.

    GO - Molecular functioni

    1. holocytochrome-c synthase activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    Keywords - Molecular functioni

    Lyase

    Keywords - Ligandi

    Heme, Iron, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable cytochrome c-type heme lyase (EC:4.4.1.17)
    Short name:
    CCHL
    Alternative name(s):
    Holocytochrome-c-type synthase
    Gene namesi
    Name:cchl-1
    ORF Names:T06D8.6
    OrganismiCaenorhabditis elegans
    Taxonomic identifieri6239 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000001940: Chromosome II

    Organism-specific databases

    WormBaseiT06D8.6; CE02327; WBGene00011527; cchl-1.

    Subcellular locationi

    GO - Cellular componenti

    1. mitochondrial inner membrane Source: UniProtKB-SubCell
    2. mitochondrion Source: WormBase

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Mitochondrion inner membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 280280Probable cytochrome c-type heme lyasePRO_0000121714Add
    BLAST

    Proteomic databases

    PaxDbiP53703.

    Interactioni

    Protein-protein interaction databases

    STRINGi6239.T06D8.6.2.

    Structurei

    3D structure databases

    ProteinModelPortaliP53703.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati35 – 406HRM 1
    Repeati56 – 616HRM 2

    Sequence similaritiesi

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    eggNOGiNOG236101.
    GeneTreeiENSGT00390000004175.
    HOGENOMiHOG000170352.
    InParanoidiP53703.
    KOiK01764.
    OMAiNNELEHP.
    PhylomeDBiP53703.

    Family and domain databases

    InterProiIPR000511. Cyt_C/C1_haem_lyase.
    [Graphical view]
    PANTHERiPTHR12743. PTHR12743. 1 hit.
    PfamiPF01265. Cyto_heme_lyase. 1 hit.
    [Graphical view]
    PROSITEiPS00821. CYTO_HEME_LYASE_1. 1 hit.
    PS00822. CYTO_HEME_LYASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P53703-1 [UniParc]FASTAAdd to Basket

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    MGSSQSTPKV QDANADAERI RKAQHSMAAA GGGSQCPLTP EQRAAASGEN    50
    CGAGGACPVG ADKASINPLN NELEHPNQKP APDQPFALPT KREKSTIPKA 100
    GTETETWTYP SPQMFWNAML KKGWRWQDDS LSKSDMENII SIHNANNEEA 150
    WREVLKWENL LHPECAEPKL KSFKGDAKNL SPRARFRNLF LGYDLPFDRH 200
    DWIVDRCGTK QVQYVIDYYD GGAVDPSSKL FTILDVRPAV NDIGNIWDRM 250
    VVAYWRFKFE TLGFTPSLPI PPTEGHNVNH 280
    Length:280
    Mass (Da):31,263
    Last modified:October 1, 1996 - v1
    Checksum:i8916E0315AA46724
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z49130 Genomic DNA. Translation: CAA88969.1.
    PIRiT24579.
    RefSeqiNP_496403.1. NM_064002.5.
    UniGeneiCel.6562.

    Genome annotation databases

    EnsemblMetazoaiT06D8.6.1; T06D8.6.1; WBGene00011527.
    T06D8.6.2; T06D8.6.2; WBGene00011527.
    GeneIDi174713.
    KEGGicel:CELE_T06D8.6.
    UCSCiT06D8.6.1. c. elegans.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z49130 Genomic DNA. Translation: CAA88969.1 .
    PIRi T24579.
    RefSeqi NP_496403.1. NM_064002.5.
    UniGenei Cel.6562.

    3D structure databases

    ProteinModelPortali P53703.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 6239.T06D8.6.2.

    Proteomic databases

    PaxDbi P53703.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai T06D8.6.1 ; T06D8.6.1 ; WBGene00011527 .
    T06D8.6.2 ; T06D8.6.2 ; WBGene00011527 .
    GeneIDi 174713.
    KEGGi cel:CELE_T06D8.6.
    UCSCi T06D8.6.1. c. elegans.

    Organism-specific databases

    CTDi 174713.
    WormBasei T06D8.6 ; CE02327 ; WBGene00011527 ; cchl-1.

    Phylogenomic databases

    eggNOGi NOG236101.
    GeneTreei ENSGT00390000004175.
    HOGENOMi HOG000170352.
    InParanoidi P53703.
    KOi K01764.
    OMAi NNELEHP.
    PhylomeDBi P53703.

    Miscellaneous databases

    NextBioi 885180.
    PROi P53703.

    Family and domain databases

    InterProi IPR000511. Cyt_C/C1_haem_lyase.
    [Graphical view ]
    PANTHERi PTHR12743. PTHR12743. 1 hit.
    Pfami PF01265. Cyto_heme_lyase. 1 hit.
    [Graphical view ]
    PROSITEi PS00821. CYTO_HEME_LYASE_1. 1 hit.
    PS00822. CYTO_HEME_LYASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      The C. elegans sequencing consortium
      Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2.

    Entry informationi

    Entry nameiCCHL_CAEEL
    AccessioniPrimary (citable) accession number: P53703
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 89 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programCaenorhabditis annotation project

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Caenorhabditis elegans
      Caenorhabditis elegans: entries, gene names and cross-references to WormBase
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3