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Reviewed, UniProtKB/Swiss-Prot P53703 (CCHL_CAEEL)

Last modified February 9, 2010. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Probable cytochrome c-type heme lyase
      Short name=CCHL
    EC=4.4.1.17
Alternative name(s):
    Holocytochrome-c-type synthase
Gene names
Name: cchl-1
ORF Names: T06D8.6
OrganismCaenorhabditis elegans [Complete proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryotaMetazoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length280 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level.

General annotation (Comments)

Function

Links covalently the heme group to the apoprotein of cytochrome c By similarity.

Catalytic activity

Holocytochrome c = apocytochrome c + heme.

Subcellular location

Mitochondrion inner membrane Potential.

Sequence similarities

Belongs to the cytochrome c-type heme lyase family.

Contains 2 HRM (heme regulatory motif) repeats.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 280280Probable cytochrome c-type heme lyase
PRO_0000121714

Regions

Repeat35 – 406HRM 1
Repeat56 – 616HRM 2

Sequences

Sequence LengthMass (Da)Tools
P53703-1 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: 8916E0315AA46724

FASTA28031,263
        10         20         30         40         50         60 
MGSSQSTPKV QDANADAERI RKAQHSMAAA GGGSQCPLTP EQRAAASGEN CGAGGACPVG 

        70         80         90        100        110        120 
ADKASINPLN NELEHPNQKP APDQPFALPT KREKSTIPKA GTETETWTYP SPQMFWNAML 

       130        140        150        160        170        180 
KKGWRWQDDS LSKSDMENII SIHNANNEEA WREVLKWENL LHPECAEPKL KSFKGDAKNL 

       190        200        210        220        230        240 
SPRARFRNLF LGYDLPFDRH DWIVDRCGTK QVQYVIDYYD GGAVDPSSKL FTILDVRPAV 

       250        260        270        280 
NDIGNIWDRM VVAYWRFKFE TLGFTPSLPI PPTEGHNVNH 

« Hide

References

[1]"Genome sequence of the nematode C. elegans: a platform for investigating biology."
The C. elegans sequencing consortium
Science 282:2012-2018(1998) [PubMed: 9851916] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Bristol N2.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z49130 Genomic DNA. Translation: CAA88969.1.
PIRT24579.
RefSeqNP_496403.1.
UniGeneCel.6562

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGP53703.

Genome annotation databases

EnsemblT06D8.6.1; T06D8.6.1; T06D8.6; Caenorhabditis elegans. [Genome view]
T06D8.6.2; T06D8.6.2; T06D8.6; Caenorhabditis elegans. [Genome view]
GeneID174713.
KEGGcel:T06D8.6.
UCSCT06D8.6.1. c. elegans.

Organism-specific databases

CTD174713.
WormBaseWBGene00011527. cchl-1.
WormPepT06D8.6. CE02327. [WorfDB]

Phylogenomic databases

eggNOGmeNOG06955.
HOGENOMHBG627179.
InParanoidP53703.
OMAALHAKEC.
PhylomeDBP53703.

Enzyme and pathway databases

BRENDA4.4.1.17. 672.

Gene expression databases

ArrayExpressP53703.

Family and domain databases

InterProIPR000511. Cyt_C/C1_haem_lyase.
[Graphical view]
PANTHERPTHR12743. Cyto_heme_lyase. 1 hit.
PfamPF01265. Cyto_heme_lyase. 1 hit.
[Graphical view]
PROSITEPS00821. CYTO_HEME_LYASE_1. 1 hit.
PS00822. CYTO_HEME_LYASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio885180.

Entry information

Entry nameCCHL_CAEEL
AccessionPrimary (citable) accession number: P53703
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: February 9, 2010
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectCaenorhabditis annotation project

Relevant documents

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormPep

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents