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Protein

Cytochrome c

Gene

CYC1

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei21Heme (covalent)PROSITE-ProRule annotation1
Binding sitei24Heme (covalent)PROSITE-ProRule annotation1
Metal bindingi25Iron (heme axial ligand)PROSITE-ProRule annotation1
Metal bindingi87Iron (heme axial ligand)PROSITE-ProRule annotation1

GO - Molecular functioni

  • electron transfer activity Source: CGD
  • heme binding Source: InterPro
  • metal ion binding Source: UniProtKB-KW

GO - Biological processi

  • mitochondrial electron transport, ubiquinol to cytochrome c Source: CGD

Keywordsi

Biological processElectron transport, Respiratory chain, Transport
LigandHeme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c
Gene namesi
Name:CYC1
Ordered Locus Names:CAALFM_C210110WA
ORF Names:CaO19.1770, CaO19.9339
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
Proteomesi
  • UP000000559 Componenti: Chromosome 2

Organism-specific databases

CGDiCAL0000196284 CYC1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001083182 – 110Cytochrome cAdd BLAST109

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei79N6,N6,N6-trimethyllysineBy similarity1

Post-translational modificationi

Binds 1 heme group per subunit.

Keywords - PTMi

Methylation

Proteomic databases

PRIDEiP53698

Structurei

3D structure databases

ProteinModelPortaliP53698
SMRiP53698
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome c family.Curated

Phylogenomic databases

InParanoidiP53698
KOiK08738
OMAiGLFKTRC
OrthoDBiEOG092C56RQ

Family and domain databases

Gene3Di1.10.760.10, 1 hit
InterProiView protein in InterPro
IPR009056 Cyt_c-like_dom
IPR036909 Cyt_c-like_dom_sf
IPR002327 Cyt_c_1A/1B
PANTHERiPTHR11961 PTHR11961, 1 hit
PfamiView protein in Pfam
PF00034 Cytochrom_C, 1 hit
PRINTSiPR00604 CYTCHRMECIAB
SUPFAMiSSF46626 SSF46626, 1 hit
PROSITEiView protein in PROSITE
PS51007 CYTC, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P53698-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPAPFEKGSE KKGATLFKTR CLQCHTVEKG GPHKVGPNLH GVFGRKSGLA
60 70 80 90 100
EGYSYTDANK KKGVEWTEQT MSDYLENPKK YIPGTKMAFG GLKKPKDRND
110
LVTYLKKATS
Length:110
Mass (Da):12,180
Last modified:January 23, 2007 - v3
Checksum:iA2B251C564DA559B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U57896 Genomic DNA Translation: AAB68996.1
CP017624 Genomic DNA Translation: AOW27988.1
RefSeqiXP_714415.1, XM_709322.1

Genome annotation databases

EnsemblFungiiAOW27988; AOW27988; CAALFM_C210110WA
GeneIDi3643937
KEGGical:CAALFM_C210110WA

Similar proteinsi

Entry informationi

Entry nameiCYC_CANAL
AccessioniPrimary (citable) accession number: P53698
Secondary accession number(s): A0A1D8PIM8, Q59XT5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: January 23, 2007
Last modified: March 28, 2018
This is version 126 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. Protein Spotlight
    Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries
  3. SIMILARITY comments
    Index of protein domains and families

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