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P53698

- CYC_CANAL

UniProt

P53698 - CYC_CANAL

Protein

Cytochrome c

Gene

CYC1

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 4 out of 5- Protein inferred from homologyi
  1. Functioni

    Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei21 – 211Heme (covalent)PROSITE-ProRule annotation
    Binding sitei24 – 241Heme (covalent)PROSITE-ProRule annotation
    Metal bindingi25 – 251Iron (heme axial ligand)PROSITE-ProRule annotation
    Metal bindingi87 – 871Iron (heme axial ligand)PROSITE-ProRule annotation

    GO - Molecular functioni

    1. electron carrier activity Source: CGD
    2. heme binding Source: InterPro
    3. iron ion binding Source: InterPro

    GO - Biological processi

    1. mitochondrial electron transport, ubiquinol to cytochrome c Source: CGD

    Keywords - Biological processi

    Electron transport, Respiratory chain, Transport

    Keywords - Ligandi

    Heme, Iron, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c
    Gene namesi
    Name:CYC1
    ORF Names:CaO19.1770, CaO19.9339
    OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
    Taxonomic identifieri237561 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
    ProteomesiUP000000559: Unassembled WGS sequence

    Organism-specific databases

    CGDiCAL0000927. CYC1.

    Subcellular locationi

    Mitochondrion intermembrane space
    Note: Loosely associated with the inner membrane.

    GO - Cellular componenti

    1. mitochondrial intermembrane space Source: UniProtKB-SubCell
    2. mitochondrion Source: CGD
    3. respiratory chain Source: UniProtKB-KW

    Keywords - Cellular componenti

    Mitochondrion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11RemovedBy similarity
    Chaini2 – 110109Cytochrome cPRO_0000108318Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei79 – 791N6,N6,N6-trimethyllysineBy similarity

    Post-translational modificationi

    Binds 1 heme group per subunit.

    Keywords - PTMi

    Methylation

    Proteomic databases

    PRIDEiP53698.

    Interactioni

    Protein-protein interaction databases

    STRINGi5476.CAL0000927.

    Structurei

    3D structure databases

    ProteinModelPortaliP53698.
    SMRiP53698. Positions 3-109.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the cytochrome c family.Curated

    Phylogenomic databases

    eggNOGiCOG3474.
    KOiK08738.
    OrthoDBiEOG71RXXT.

    Family and domain databases

    Gene3Di1.10.760.10. 1 hit.
    InterProiIPR009056. Cyt_c-like_dom.
    IPR002327. Cyt_c_1A/1B.
    IPR003088. Cyt_c_dom.
    [Graphical view]
    PANTHERiPTHR11961. PTHR11961. 1 hit.
    PfamiPF00034. Cytochrom_C. 1 hit.
    [Graphical view]
    PRINTSiPR00604. CYTCHRMECIAB.
    SUPFAMiSSF46626. SSF46626. 1 hit.
    PROSITEiPS51007. CYTC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P53698-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPAPFEKGSE KKGATLFKTR CLQCHTVEKG GPHKVGPNLH GVFGRKSGLA    50
    EGYSYTDANK KKGVEWTEQT MSDYLENPKK YIPGTKMAFG GLKKPKDRND 100
    LVTYLKKATS 110
    Length:110
    Mass (Da):12,180
    Last modified:January 23, 2007 - v3
    Checksum:iA2B251C564DA559B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U57896 Genomic DNA. Translation: AAB68996.1.
    AACQ01000105 Genomic DNA. Translation: EAK95307.1.
    AACQ01000104 Genomic DNA. Translation: EAK95348.1.
    RefSeqiXP_714375.1. XM_709282.1.
    XP_714415.1. XM_709322.1.

    Genome annotation databases

    GeneIDi3643937.
    3644007.
    KEGGical:CaO19.1770.
    cal:CaO19.9339.

    Cross-referencesi

    Web resourcesi

    Protein Spotlight

    Life shuttle - Issue 76 of November 2006

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U57896 Genomic DNA. Translation: AAB68996.1 .
    AACQ01000105 Genomic DNA. Translation: EAK95307.1 .
    AACQ01000104 Genomic DNA. Translation: EAK95348.1 .
    RefSeqi XP_714375.1. XM_709282.1.
    XP_714415.1. XM_709322.1.

    3D structure databases

    ProteinModelPortali P53698.
    SMRi P53698. Positions 3-109.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5476.CAL0000927.

    Proteomic databases

    PRIDEi P53698.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3643937.
    3644007.
    KEGGi cal:CaO19.1770.
    cal:CaO19.9339.

    Organism-specific databases

    CGDi CAL0000927. CYC1.

    Phylogenomic databases

    eggNOGi COG3474.
    KOi K08738.
    OrthoDBi EOG71RXXT.

    Family and domain databases

    Gene3Di 1.10.760.10. 1 hit.
    InterProi IPR009056. Cyt_c-like_dom.
    IPR002327. Cyt_c_1A/1B.
    IPR003088. Cyt_c_dom.
    [Graphical view ]
    PANTHERi PTHR11961. PTHR11961. 1 hit.
    Pfami PF00034. Cytochrom_C. 1 hit.
    [Graphical view ]
    PRINTSi PR00604. CYTCHRMECIAB.
    SUPFAMi SSF46626. SSF46626. 1 hit.
    PROSITEi PS51007. CYTC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Phylogenetic relationships of fungal cytochromes c."
      Janbon G., Rustchenko E., Klug S., Scherer S., Sherman F.
      Yeast 13:985-990(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: SOR17.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SC5314 / ATCC MYA-2876.

    Entry informationi

    Entry nameiCYC_CANAL
    AccessioniPrimary (citable) accession number: P53698
    Secondary accession number(s): Q59XT5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 105 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Candida albicans
      Candida albicans: entries and gene names
    2. Protein Spotlight
      Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3