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P53697

- MNN9_CANAL

UniProt

P53697 - MNN9_CANAL

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Protein
Mannan polymerase complex subunit MNN9
Gene
MNN9, CaO19.7383
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 5 out of 5 - Protein inferred from homologyi

Functioni

Required for the addition of the long alpha 1,6-mannose backbone of N-linked glycans on cell wall and periplasmic proteins.

Pathwayi

GO - Molecular functioni

  1. mannosyltransferase activity Source: CGD

GO - Biological processi

  1. cell wall mannoprotein biosynthetic process Source: CGD
  2. cellular response to drug Source: CGD
  3. cellular response to heat Source: CGD
  4. filamentous growth Source: CGD
  5. filamentous growth of a population of unicellular organisms in response to biotic stimulus Source: CGD
  6. filamentous growth of a population of unicellular organisms in response to heat Source: CGD
  7. fungal-type cell wall organization Source: CGD
  8. mannosylation Source: GOC
  9. protein glycosylation Source: UniProtKB-UniPathway
Complete GO annotation...

Enzyme and pathway databases

UniPathwayiUPA00378.

Protein family/group databases

CAZyiGT62. Glycosyltransferase Family 62.

Names & Taxonomyi

Protein namesi
Recommended name:
Mannan polymerase complex subunit MNN9
Gene namesi
Name:MNN9
ORF Names:CaO19.7383
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
ProteomesiUP000000559: Unassembled WGS sequence

Organism-specific databases

CGDiCAL0004800. MNN9.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 1515Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei16 – 3318Helical; Signal-anchor for type II membrane protein
Add
BLAST
Topological domaini34 – 368335Lumenal Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. Golgi membrane Source: UniProtKB-SubCell
  2. integral component of membrane Source: CGD
  3. plasma membrane Source: CGD
Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 368368Mannan polymerase complex subunit MNN9
PRO_0000193669Add
BLAST

Interactioni

Protein-protein interaction databases

BioGridi1224829. 1 interaction.
STRINGi5476.CAL0004800.

Family & Domainsi

Sequence similaritiesi

Belongs to the ANP1/MMN9/VAN1 family.

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG73762.
KOiK05529.
OrthoDBiEOG73V6VP.

Family and domain databases

InterProiIPR005109. Anp1.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamiPF03452. Anp1. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 2 hits.

Sequencei

Sequence statusi: Complete.

P53697-1 [UniParc]FASTAAdd to Basket

« Hide

MVHYRNRYLN YIRRKPLALL APITLLVVIY FYFFSAHGFS SNKQKYNYNK    50
KSRGWFYKNR DTVILKDLPK NHISHYDLNK LTASKDALNK REEVLILTPM 100
SKFLPEYWEN INKLTYDHSL ISLGFIFPRT TQGDDALKEL ENALKKTKRE 150
KRLNFKKITI LRQDSNSLQS QLEKDRHAFK VQKERRSMMA LARNSLVFST 200
ILPSTSWVLW LDADIVETPV TLIQDLTGHN KPVVSANVHQ RFINQDTKQP 250
DIRPYDFNNW VESEEGLKLA ASLPDDEIIV EGYSEMVTHR ALMAHFYDPK 300
GDPSTEMTLD GVGGGAVMVK ADVHRDGAMF PSFPFYHLIE TEGFAKMAKR 350
LGYEVYGLPN YLVFHYNE 368
Length:368
Mass (Da):42,782
Last modified:October 1, 1996 - v1
Checksum:i930DCC64EE8F5EF5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U63642 Genomic DNA. Translation: AAB05924.1.
AACQ01000066 Genomic DNA. Translation: EAK97629.1.
RefSeqiXP_716624.1. XM_711531.1.

Genome annotation databases

GeneIDi3641735.
KEGGical:CaO19.7383.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U63642 Genomic DNA. Translation: AAB05924.1 .
AACQ01000066 Genomic DNA. Translation: EAK97629.1 .
RefSeqi XP_716624.1. XM_711531.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 1224829. 1 interaction.
STRINGi 5476.CAL0004800.

Protein family/group databases

CAZyi GT62. Glycosyltransferase Family 62.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3641735.
KEGGi cal:CaO19.7383.

Organism-specific databases

CGDi CAL0004800. MNN9.

Phylogenomic databases

eggNOGi NOG73762.
KOi K05529.
OrthoDBi EOG73V6VP.

Enzyme and pathway databases

UniPathwayi UPA00378 .

Family and domain databases

InterProi IPR005109. Anp1.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view ]
Pfami PF03452. Anp1. 1 hit.
[Graphical view ]
SUPFAMi SSF53448. SSF53448. 2 hits.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular analysis of the Candida albicans homolog of Saccharomyces cerevisiae MNN9, required for glycosylation of cell wall mannoproteins."
    Southard S.B., Specht C.A., Mishra C., Chen-Weiner J., Robbins P.W.
    J. Bacteriol. 181:7439-7448(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 10261 / CBS 2718 / NBRC 1061.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SC5314 / ATCC MYA-2876.

Entry informationi

Entry nameiMNN9_CANAL
AccessioniPrimary (citable) accession number: P53697
Secondary accession number(s): Q5A4F1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: June 11, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Candida albicans
    Candida albicans: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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