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Protein

Mannan polymerase complex subunit MNN9

Gene

MNN9

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Required for the addition of the long alpha 1,6-mannose backbone of N-linked glycans on cell wall and periplasmic proteins.

Pathwayi: protein glycosylation

This protein is involved in the pathway protein glycosylation, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein glycosylation and in Protein modification.

GO - Molecular functioni

  • mannosyltransferase activity Source: CGD

GO - Biological processi

  • cellular response to drug Source: CGD
  • cellular response to heat Source: CGD
  • cell wall mannoprotein biosynthetic process Source: CGD
  • filamentous growth Source: CGD
  • filamentous growth of a population of unicellular organisms in response to biotic stimulus Source: CGD
  • filamentous growth of a population of unicellular organisms in response to heat Source: CGD
  • fungal-type cell wall organization Source: CGD
  • protein glycosylation Source: UniProtKB-UniPathway

Enzyme and pathway databases

UniPathwayiUPA00378

Protein family/group databases

CAZyiGT62 Glycosyltransferase Family 62

Names & Taxonomyi

Protein namesi
Recommended name:
Mannan polymerase complex subunit MNN9
Gene namesi
Name:MNN9
Ordered Locus Names:CAALFM_C306020WA
ORF Names:CaO19.7383
OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic identifieri237561 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
Proteomesi
  • UP000000559 Componenti: Chromosome 3

Organism-specific databases

CGDiCAL0000179486 MNN9
EuPathDBiFungiDB:C3_06020W_A

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 15CytoplasmicSequence analysisAdd BLAST15
Transmembranei16 – 33Helical; Signal-anchor for type II membrane proteinAdd BLAST18
Topological domaini34 – 368LumenalSequence analysisAdd BLAST335

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001936691 – 368Mannan polymerase complex subunit MNN9Add BLAST368

Proteomic databases

PRIDEiP53697

Interactioni

Protein-protein interaction databases

BioGridi1224829, 1 interactor

Structurei

3D structure databases

SMRiP53697
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ANP1/MMN9/VAN1 family.Curated

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiP53697
KOiK05529
OMAiFNSWQDS
OrthoDBiEOG092C2GA4

Family and domain databases

Gene3Di3.90.550.10, 1 hit
InterProiView protein in InterPro
IPR029044 Nucleotide-diphossugar_trans
SUPFAMiSSF53448 SSF53448, 2 hits

Sequencei

Sequence statusi: Complete.

P53697-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVHYRNRYLN YIRRKPLALL APITLLVVIY FYFFSAHGFS SNKQKYNYNK
60 70 80 90 100
KSRGWFYKNR DTVILKDLPK NHISHYDLNK LTASKDALNK REEVLILTPM
110 120 130 140 150
SKFLPEYWEN INKLTYDHSL ISLGFIFPRT TQGDDALKEL ENALKKTKRE
160 170 180 190 200
KRLNFKKITI LRQDSNSLQS QLEKDRHAFK VQKERRSMMA LARNSLVFST
210 220 230 240 250
ILPSTSWVLW LDADIVETPV TLIQDLTGHN KPVVSANVHQ RFINQDTKQP
260 270 280 290 300
DIRPYDFNNW VESEEGLKLA ASLPDDEIIV EGYSEMVTHR ALMAHFYDPK
310 320 330 340 350
GDPSTEMTLD GVGGGAVMVK ADVHRDGAMF PSFPFYHLIE TEGFAKMAKR
360
LGYEVYGLPN YLVFHYNE
Length:368
Mass (Da):42,782
Last modified:October 1, 1996 - v1
Checksum:i930DCC64EE8F5EF5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U63642 Genomic DNA Translation: AAB05924.1
CP017625 Genomic DNA Translation: AOW28610.1
RefSeqiXP_716624.1, XM_711531.1

Genome annotation databases

EnsemblFungiiAOW28610; AOW28610; CAALFM_C306020WA
GeneIDi3641735
KEGGical:CAALFM_C306020WA

Similar proteinsi

Entry informationi

Entry nameiMNN9_CANAL
AccessioniPrimary (citable) accession number: P53697
Secondary accession number(s): A0A1D8PKF7, Q5A4F1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: March 28, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health