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Protein

Superoxide dismutase [Mn]

Gene

sodA

Organism
Thermus aquaticus
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.

Cofactori

Mn2+By similarityNote: Binds 1 Mn2+ ion per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi29ManganeseBy similarity1
Metal bindingi84ManganeseBy similarity1
Metal bindingi167ManganeseBy similarity1
Metal bindingi171ManganeseBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandManganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Mn] (EC:1.15.1.1)
Gene namesi
Name:sodA
OrganismiThermus aquaticus
Taxonomic identifieri271 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001601062 – 204Superoxide dismutase [Mn]Add BLAST203

Proteomic databases

PRIDEiP53653.

Interactioni

Subunit structurei

Homotetramer.By similarity

Structurei

3D structure databases

ProteinModelPortaliP53653.
SMRiP53653.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105CK4. Bacteria.
COG0605. LUCA.

Family and domain databases

Gene3Di1.10.287.990. 1 hit.
2.40.500.20. 1 hit.
InterProiView protein in InterPro
IPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
IPR036324. Mn/Fe_SOD_N_sf.
IPR036314. SOD_C_sf.
PfamiView protein in Pfam
PF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiView protein in PROSITE
PS00088. SOD_MN. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P53653-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPYPFKLPEL GYPYEALEPH IDARTMEIHH QKHHGAYVTN LNAALEKYPY
60 70 80 90 100
LQGAEVETLL RHLTALPADI QAAVRNNGGG HLNHSLFWRL LTPGGAKEPV
110 120 130 140 150
GELKKAIDEQ FGGFAALKEK LTQAAMGRFG SGWAWLVKDP FGKLHVISTA
160 170 180 190 200
NQDNPVMGGF APIVGIDVWE HAYYLKYQNR RADYLQAIWN VLNWDVAEEI

YKGA
Length:204
Mass (Da):22,905
Last modified:January 23, 2007 - v2
Checksum:iBE36CABCE5C6BA0D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D13387 Genomic DNA. Translation: BAA02655.1.
D84646 Genomic DNA. Translation: BAA12703.1.
PIRiT45270.

Similar proteinsi

Entry informationi

Entry nameiSODM_THEAQ
AccessioniPrimary (citable) accession number: P53653
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: January 23, 2007
Last modified: March 28, 2018
This is version 74 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program