P53645 (SODM_MYCMA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Superoxide dismutase [Mn]
EC=1.15.1.1

Gene names

Name:	sodA
Synonyms:	sod

Organism

Mycobacterium malmoense

Taxonomic identifier

1780 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	138 AA.
Sequence status	Fragment.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
Catalytic activity	2 superoxide + 2 H+ = O2 + H2O2.
Cofactor	Binds 1 manganese ion per subunit By similarity.
Sequence similarities	Belongs to the iron/manganese superoxide dismutase family.

Ontologies

Keywords
Ligand	Manganese Metal-binding
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological_process	superoxide metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW superoxide dismutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – ›138	›138	Superoxide dismutase [Mn]		PRO_0000160054
Sites
	Metal binding	1	1	Manganese By similarity
	Metal binding	49	1	Manganese By similarity
	Metal binding	133	1	Manganese By similarity
	Metal binding	137	1	Manganese By similarity
Experimental info
	Non-terminal residue	1	1
	Non-terminal residue	138	1

Sequences

	Sequence		Length	Mass (Da)
	P53645 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 38D8E022BEC59EC1	FASTA	138	15,046
	10 20 30 40 50 60 HHSKHHAAYV KGVNDAVAKL EEARAKDDHS AIFLNEKNLA FHLGGHVNHS IWWKNLSPNG 70 80 90 100 110 120 GDKPTGDLAS AIDDAFGSFD KFRAQFSAAA NGLQGSGWAV LGYDSLGDKL LTFQLYDQQA 130 NVPLGIIPLL QVDMWEHA

References

[1]	"Rapid identification of mycobacteria from AIDS patients by capillary electrophoretic profiling of amplified SOD gene." Bull T.J., Shanson D.C., Archard L.C. Clin. Mol. Pathol. 48:124-132(1995) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: NCTC 11298.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z48210 Genomic DNA. Translation: CAA88243.1.
PIR	S52364.
3D structure databases
ProteinModelPortal	P53645.
SMR	P53645. Positions 1-138.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR001189. Mn/Fe_SOD. IPR019832. Mn/Fe_SOD_C. IPR019831. Mn/Fe_SOD_N. [Graphical view]
PANTHER	PTHR11404. PTHR11404. 1 hit.
Pfam	PF02777. Sod_Fe_C. 1 hit. PF00081. Sod_Fe_N. 1 hit. [Graphical view]
PRINTS	PR01703. MNSODISMTASE.
SUPFAM	SSF46609. SODismutase. 1 hit. SSF54719. SODismutase. 1 hit.
PROSITE	PS00088. SOD_MN. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SODM_MYCMA

Accession

Primary (citable) accession number: P53645

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	October 3, 2012
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program