P53642 (SODM_BORPE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Superoxide dismutase [Mn]
EC=1.15.1.1

Gene names

Name:	sodA
Ordered Locus Names:	BP0193

Organism

Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) [Reference proteome] [HAMAP]

Taxonomic identifier

257313 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella › Bordetella pertussis

Protein attributes

Sequence length	211 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
Catalytic activity	2 superoxide + 2 H+ = O2 + H2O2.
Cofactor	Binds 1 manganese ion per subunit By similarity.
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the iron/manganese superoxide dismutase family.

Ontologies

Keywords
Ligand	Manganese Metal-binding
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	superoxide metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW superoxide dismutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 211	211	Superoxide dismutase [Mn]		PRO_0000160021
Sites
	Metal binding	27	1	Manganese By similarity
	Metal binding	82	1	Manganese By similarity
	Metal binding	165	1	Manganese By similarity
	Metal binding	169	1	Manganese By similarity

Sequences

	Sequence		Length	Mass (Da)
	P53642 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 354903AF71136CD8	FASTA	211	23,212
	10 20 30 40 50 60 MPYVLPALSY AYDALEPHID ARTMEIHHTR HHQTYVNGLN AALEGAGLDS EEPVEQLLRR 70 80 90 100 110 120 IPALPPGIHG AVRNHGGGHA NHSLLWTVMS PSGGGRPDGR LAADIQAQLG GHDAFQAAFT 130 140 150 160 170 180 QAALGRFGSG WAWLTVTPAG RLRVDSSANQ DSPLMEGNTP ILGLDVWEHA YYLQYQNRRP 190 200 210 EYIEAFYRVV DWAEVARRYE IALAELGREA A

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning and characterization of an Mn-containing superoxide dismutase (SodA) of Bordetella pertussis." Graeff-Wohlleben H., Killat S., Banemann A., Guiso N., Gross R. J. Bacteriol. 179:2194-2201(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Tohama I / ATCC BAA-589 / NCTC 13251.
[2]	"Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica." Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R., Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L., Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A., Achtman M., Atkin R., Baker S. , Basham D., Bason N., Cherevach I., Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S., Barrell B.G., Maskell D.J. Nat. Genet. 35:32-40(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tohama I / ATCC BAA-589 / NCTC 13251.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X84800 Genomic DNA. Translation: CAA59267.1. BX640411 Genomic DNA. Translation: CAE40572.1.
RefSeq	NP_879082.1. NC_002929.2.
3D structure databases
ProteinModelPortal	P53642.
SMR	P53642. Positions 3-199.
ModBase	Search...
Protein-protein interaction databases
STRING	257313.BP0193.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAE40572; CAE40572; BP0193.
GeneID	2664387.
KEGG	bpe:BP0193.
PATRIC	21153394. VBIBorPer7866_0204.
Phylogenomic databases
eggNOG	COG0605.
HOGENOM	HOG000013583.
KO	K04564.
OMA	WTVMAPN.
ProtClustDB	CLSK266401.
Enzyme and pathway databases
BioCyc	BPER257313:BP0193-MONOMER.
Family and domain databases
InterPro	IPR001189. Mn/Fe_SOD. IPR019833. Mn/Fe_SOD_BS. IPR019832. Mn/Fe_SOD_C. IPR019831. Mn/Fe_SOD_N. [Graphical view]
PANTHER	PTHR11404. PTHR11404. 1 hit.
Pfam	PF02777. Sod_Fe_C. 1 hit. PF00081. Sod_Fe_N. 1 hit. [Graphical view]
PIRSF	PIRSF000349. SODismutase. 1 hit.
PRINTS	PR01703. MNSODISMTASE.
SUPFAM	SSF46609. SODismutase. 1 hit. SSF54719. SODismutase. 1 hit.
PROSITE	PS00088. SOD_MN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SODM_BORPE

Accession

Primary (citable) accession number: P53642

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	May 1, 2013
This is version 88 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program