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P53633 (PRA1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 90. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Prenylated Rab acceptor 1
Gene names
Name:YIP3
Synonyms:PRA1
Ordered Locus Names:YNL044W
ORF Names:N2650
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length176 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Interacts with YIP1 and the Rab GTPases SEC4, YPT1, YPT6, YPT10, YPT11, YPT31, YPT32 and YPT52. Ref.5

Subcellular location

Golgi apparatus membrane; Multi-pass membrane protein Ref.6.

Miscellaneous

Present with 5500 molecules/cell in log phase SD medium. Ref.7

Sequence similarities

Belongs to the PRA1 family.

Sequence caution

The sequence CAA64238.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 176176Prenylated Rab acceptor 1
PRO_0000220887

Regions

Transmembrane84 – 10421Helical; Potential
Transmembrane129 – 14921Helical; Potential

Amino acid modifications

Modified residue181Phosphoserine Ref.8

Experimental info

Sequence conflict291L → F in CAA66057. Ref.1
Sequence conflict291L → F in CAA66058. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P53633 [UniParc].

Last modified October 3, 2006. Version 2.
Checksum: C88401CB23197CD8

FASTA17619,412
        10         20         30         40         50         60 
MNQLGALAQV SRFTQNFSME NIKSEFQSLQ SKLATLRTPQ EFFNFKKISK PQNFGEVQSR 

        70         80         90        100        110        120 
VAYNLKYFSS NYGLIIGCLS IYTLLTNLLL LFVIVLVVAG IVGINKLKGE ELVTPFGSFK 

       130        140        150        160        170 
TNQLYTGLVC VAVPIGFLAS PISTLLWLIG ASAVSVFGHA SLMEKPIETV FDEETV

« Hide

References

« Hide 'large scale' references
[1]Matern H.T., Gallwitz D.
Submitted (APR-1996) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
[2]"The sequence of 12.8 kb from the left arm of chromosome XIV reveals a sigma element, a pro-tRNA and six complete open reading frames, one of which encodes a protein similar to the human leukotriene A4 hydrolase."
Nasr F., Becam A.-M., Herbert C.J.
Yeast 12:493-499(1996) [PubMed: 8740423] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 96604 / S288c / FY1679.
[3]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications."
Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J. expand/collapse author list , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.
Nature 387:93-98(1997) [PubMed: 9169873] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[4]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[5]"Saccharomyces cerevisiae Pra1p/Yip3p interacts with Yip1p and Rab proteins."
Calero M., Collins R.N.
Biochem. Biophys. Res. Commun. 290:676-681(2002) [PubMed: 11785952] [Abstract]
Cited for: INTERACTION WITH SEC4; YIP1; YPT1; YPT6; YPT10; YPT11; YPT31; YPT32 AND YPT52.
[6]"Global analysis of protein localization in budding yeast."
Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K.
Nature 425:686-691(2003) [PubMed: 14562095] [Abstract]
Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[7]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed: 14562106] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[8]"A multidimensional chromatography technology for in-depth phosphoproteome analysis."
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed: 18407956] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-18, MASS SPECTROMETRY.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		X97400 Genomic DNA. Translation: CAA66057.1.
X97401 mRNA. Translation: CAA66058.1.
X94547 Genomic DNA. Translation: CAA64238.1. Sequence problems.
Z71320 Genomic DNA. Translation: CAA95911.1.
Z71321 Genomic DNA. Translation: CAA95913.1.
BK006947 Genomic DNA. Translation: DAA10501.1.
PIRS61100.
RefSeqNP_014354.2. NM_001182883.1.

3D structure databases

ProteinModelPortalP53633.
ModBaseSearch...

Protein-protein interaction databases

DIPDIP-2059N.
IntActP53633. 29 interactions.
MINTMINT-490369.
STRINGP53633.

Proteomic databases

PeptideAtlasP53633.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYNL044W; YNL044W; YNL044W.
GeneID855683.
KEGGsce:YNL044W.
NMPDRfig|4932.3.peg.5430.

Organism-specific databases

CYGDYNL044w.
SGDS000004989. YIP3.

Phylogenomic databases

eggNOGfuNOG10377.
GeneTreeEFGT00050000005642.
HOGENOMHBG738032.
OMAMEKPIET.
OrthoDBEOG43BQZK.

Gene expression databases

ArrayExpressP53633.
GenevestigatorP53633.
GermOnlineYNL044W. Saccharomyces cerevisiae.

Family and domain databases

InterProIPR004895. Prenylated_rab_accept_PRA1.
[Graphical view]
PfamPF03208. PRA1. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio979987.

Entry information

Entry namePRA1_YEAST
AccessionPrimary (citable) accession number: P53633
Secondary accession number(s): D6W1D5
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 3, 2006
Last modified: December 14, 2011
This is version 90 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Yeast chromosome XIV

Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

SIMILARITY comments

Index of protein domains and families

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