Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Serum amyloid A protein

Gene

SAA1

Organism
Macropus eugenii (Tammar wallaby) (Notamacropus eugenii)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Major acute phase reactant. Apolipoprotein of the HDL complex.

GO - Biological processi

Keywordsi

Biological processAcute phase

Names & Taxonomyi

Protein namesi
Recommended name:
Serum amyloid A protein
Short name:
SAA
Gene namesi
Name:SAA1
OrganismiMacropus eugenii (Tammar wallaby) (Notamacropus eugenii)
Taxonomic identifieri9315 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMetatheriaDiprotodontiaMacropodidaeNotamacropus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

HDL, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_000003158419 – 127Serum amyloid A proteinAdd BLAST109

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei19Pyrrolidone carboxylic acidBy similarity1

Keywords - PTMi

Pyrrolidone carboxylic acid

Expressioni

Tissue specificityi

Expressed by the liver; secreted in plasma.

Structurei

3D structure databases

SMRiP53613.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SAA family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000126881.
HOVERGENiHBG016327.
OrthoDBiEOG091G17YH.
TreeFamiTF332544.

Family and domain databases

InterProiView protein in InterPro
IPR000096. Serum_amyloid_A.
PfamiView protein in Pfam
PF00277. SAA. 1 hit.
PIRSFiPIRSF002472. Serum_amyloid_A. 1 hit.
PRINTSiPR00306. SERUMAMYLOID.
SMARTiView protein in SMART
SM00197. SAA. 1 hit.
PROSITEiView protein in PROSITE
PS00992. SAA. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P53613-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLLTSLFLL SLVLCVNSQG WLRDSLDFLN QARLGAGDMW RAYRDMREAN
60 70 80 90 100
FKNSDKYFHA RGNYDAAKRG PGGVWAAEVL SDAREFLQGG SSGRGVEDSM
110 120
ADQEANRWGR SGKDPNRYRP KGLDPKY
Length:127
Mass (Da):14,322
Last modified:October 1, 1996 - v1
Checksum:iD2405776418F48FB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U39363 mRNA. Translation: AAB02187.1.

Similar proteinsi

Entry informationi

Entry nameiSAA_MACEU
AccessioniPrimary (citable) accession number: P53613
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: August 30, 2017
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families