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Protein

Protein MSO1

Gene

MSO1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in secretion. Component of the secretory vesicle docking complex.

Miscellaneous

Present with 1380 molecules/cell in log phase SD medium.1 Publication

GO - Biological processi

  • ascospore-type prospore membrane assembly Source: SGD
  • membrane fusion Source: SGD
  • protein transport Source: UniProtKB-KW
  • vesicle docking involved in exocytosis Source: SGD

Keywordsi

Biological processProtein transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-33356-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein MSO1
Gene namesi
Name:MSO1
Ordered Locus Names:YNR049C
ORF Names:N3457
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIV

Organism-specific databases

EuPathDBiFungiDB:YNR049C
SGDiS000005332 MSO1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000966001 – 210Protein MSO1Add BLAST210
Isoform 2 (identifier: P53604-2)
Initiator methionineiRemovedCombined sources

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1N-acetylmethionineCombined sources1
Modified residuei102PhosphoserineCombined sources1
Isoform 2 (identifier: P53604-2)
Modified residuei2N-acetylserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiP53604
PaxDbiP53604
PRIDEiP53604

PTM databases

iPTMnetiP53604

Interactioni

Subunit structurei

Interacts physically with SEC1.

Protein-protein interaction databases

BioGridi35874, 116 interactors
DIPiDIP-2499N
IntActiP53604, 4 interactors
MINTiP53604
STRINGi4932.YNR049C

Structurei

3D structure databases

ProteinModelPortaliP53604
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000057081
InParanoidiP53604
KOiK19992
OrthoDBiEOG092C5HMN

Family and domain databases

InterProiView protein in InterPro
IPR028095 Mso1_N_dom
PfamiView protein in Pfam
PF14475 Mso1_Sec1_bdg, 1 hit

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative initiation. AlignAdd to basket

Isoform 1 (identifier: P53604-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MMSQVSHSQE GSGRFWNKFK SSTKSLSTSL AHLSIKAEKD GDTVNTTLVH
60 70 80 90 100
KGLVKFYENQ HPFQGFPGWL GEKEDLPNER KILDTQVKHD MKKQNSRHFS
110 120 130 140 150
PSFSNRRKAS SEDPMGTPSS NGNTPEYTPA SKSFQDIYNN HTSSSSATPR
160 170 180 190 200
RASSRPTRPS AGQEFRASLG RSKTSNSFNT SSTPTPPPDA SSGVMAMKDR
210
LKRRNNDYGF
Length:210
Mass (Da):23,351
Last modified:October 1, 1996 - v1
Checksum:iC51AC383A149DA46
GO
Isoform 2 (identifier: P53604-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: Missing.

Show »
Length:209
Mass (Da):23,220
Checksum:iA1F945A8BD075C5A
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0581251Missing in isoform 2. Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U56416 Genomic DNA Translation: AAB01212.1
Z71664 Genomic DNA Translation: CAA96330.1
AY558423 Genomic DNA Translation: AAS56749.1
BK006947 Genomic DNA Translation: DAA10590.1
PIRiS63380
RefSeqiNP_014447.3, NM_001183226.3 [P53604-1]

Genome annotation databases

EnsemblFungiiYNR049C; YNR049C; YNR049C [P53604-1]
GeneIDi855785
KEGGisce:YNR049C

Keywords - Coding sequence diversityi

Alternative initiation

Similar proteinsi

Entry informationi

Entry nameiMSO1_YEAST
AccessioniPrimary (citable) accession number: P53604
Secondary accession number(s): D6W1M4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: March 28, 2018
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health