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Protein

Protein MSO1

Gene

MSO1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Involved in secretion. Component of the secretory vesicle docking complex.

GO - Biological processi

  1. ascospore-type prospore membrane assembly Source: SGD
  2. membrane fusion Source: SGD
  3. protein transport Source: UniProtKB-KW
  4. vesicle docking involved in exocytosis Source: SGD
Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-33356-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein MSO1
Gene namesi
Name:MSO1
Ordered Locus Names:YNR049C
ORF Names:N3457
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome XIV

Organism-specific databases

CYGDiYNR049c.
SGDiS000005332. MSO1.

Subcellular locationi

GO - Cellular componenti

  1. cellular bud membrane Source: SGD
  2. cellular bud neck Source: SGD
  3. cellular bud tip Source: SGD
  4. plasma membrane Source: SGD
  5. prospore membrane Source: SGD
  6. SNARE complex Source: SGD
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 210210Protein MSO1PRO_0000096600Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylmethionine1 Publication
Modified residuei102 – 1021Phosphoserine1 Publication

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiP53604.
PaxDbiP53604.

Expressioni

Gene expression databases

GenevestigatoriP53604.

Interactioni

Subunit structurei

Interacts physically with SEC1.

Protein-protein interaction databases

BioGridi35874. 47 interactions.
DIPiDIP-2499N.
IntActiP53604. 2 interactions.
MINTiMINT-4501308.
STRINGi4932.YNR049C.

Structurei

3D structure databases

ProteinModelPortaliP53604.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiNOG68784.
HOGENOMiHOG000057081.
InParanoidiP53604.
OrthoDBiEOG7QRR7B.

Family and domain databases

InterProiIPR028095. Mso1_N_dom.
[Graphical view]
PfamiPF14475. Mso1_Sec1_bdg. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P53604-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMSQVSHSQE GSGRFWNKFK SSTKSLSTSL AHLSIKAEKD GDTVNTTLVH
60 70 80 90 100
KGLVKFYENQ HPFQGFPGWL GEKEDLPNER KILDTQVKHD MKKQNSRHFS
110 120 130 140 150
PSFSNRRKAS SEDPMGTPSS NGNTPEYTPA SKSFQDIYNN HTSSSSATPR
160 170 180 190 200
RASSRPTRPS AGQEFRASLG RSKTSNSFNT SSTPTPPPDA SSGVMAMKDR
210
LKRRNNDYGF
Length:210
Mass (Da):23,351
Last modified:October 1, 1996 - v1
Checksum:iC51AC383A149DA46
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U56416 Genomic DNA. Translation: AAB01212.1.
Z71664 Genomic DNA. Translation: CAA96330.1.
AY558423 Genomic DNA. Translation: AAS56749.1.
BK006947 Genomic DNA. Translation: DAA10590.1.
PIRiS63380.
RefSeqiNP_014447.3. NM_001183226.3.

Genome annotation databases

EnsemblFungiiYNR049C; YNR049C; YNR049C.
GeneIDi855785.
KEGGisce:YNR049C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U56416 Genomic DNA. Translation: AAB01212.1.
Z71664 Genomic DNA. Translation: CAA96330.1.
AY558423 Genomic DNA. Translation: AAS56749.1.
BK006947 Genomic DNA. Translation: DAA10590.1.
PIRiS63380.
RefSeqiNP_014447.3. NM_001183226.3.

3D structure databases

ProteinModelPortaliP53604.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi35874. 47 interactions.
DIPiDIP-2499N.
IntActiP53604. 2 interactions.
MINTiMINT-4501308.
STRINGi4932.YNR049C.

Proteomic databases

MaxQBiP53604.
PaxDbiP53604.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYNR049C; YNR049C; YNR049C.
GeneIDi855785.
KEGGisce:YNR049C.

Organism-specific databases

CYGDiYNR049c.
SGDiS000005332. MSO1.

Phylogenomic databases

eggNOGiNOG68784.
HOGENOMiHOG000057081.
InParanoidiP53604.
OrthoDBiEOG7QRR7B.

Enzyme and pathway databases

BioCyciYEAST:G3O-33356-MONOMER.

Miscellaneous databases

NextBioi980262.

Gene expression databases

GenevestigatoriP53604.

Family and domain databases

InterProiIPR028095. Mso1_N_dom.
[Graphical view]
PfamiPF14475. Mso1_Sec1_bdg. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Mso1p: a yeast protein that functions in secretion and interacts physically and genetically with Sec1p."
    Aalto M.K., Jantti J., Ostling J., Keranen S., Ronne H.
    Proc. Natl. Acad. Sci. U.S.A. 94:7331-7336(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 208353 / W303-1A.
  2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications."
    Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J.
    , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.
    Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  6. "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae."
    Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J., Elias J.E., Gygi S.P.
    J. Proteome Res. 6:1190-1197(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-102, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Strain: ADR376.
  7. "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
    Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
    Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  8. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiMSO1_YEAST
AccessioniPrimary (citable) accession number: P53604
Secondary accession number(s): D6W1M4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: January 7, 2015
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 1380 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XIV
    Yeast (Saccharomyces cerevisiae) chromosome XIV: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.