P53583 (MPA43_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein MPA43

Gene names

Name:	MPA43
Ordered Locus Names:	YNL249C
ORF Names:	N0875

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	542 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Miscellaneous

Present with 1050 molecules/cell in log phase SD medium.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	mitochondrion Inferred from direct assay PubMed 14576278PubMed 16823961. Source: SGD
Molecular_function	phosphotransferase activity, alcohol group as acceptor Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 542	542	Protein MPA43		PRO_0000096549
Experimental info
	Sequence conflict	46 – 53	8	KKSWKFWQ → RSHGNLA in CAA63905. Ref.5

Sequences

	Sequence		Length	Mass (Da)
	P53583 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 830AA8D4E95365AD	FASTA	542	61,667
	10 20 30 40 50 60 MNSSLQVGIG IDVGSSSARI GVYNYYNDAL LEMAQEPVPY YQDSSKKSWK FWQKSTEIIK 70 80 90 100 110 120 ALQKCLQKLN IREYEVKSCG VSATCSLAIF ERDRTSNMLI PYPNEDNVIF WMDSSAVNEC 130 140 150 160 170 180 QWLNMQCPQQ LLDYLGGKFV PEMGVPKLKY FLDEYSHLRD KHFHIFDLHQ YIAYELSRLY 190 200 210 220 230 240 EWNIEGLLGR ENLNGIGNDG EVSGWSSSFY KNIINLPSNV SIGTTSLVAN KHISTTVVRS 250 260 270 280 290 300 CIDSYASWFA VASPHLETSL FMIAGTSSCY MYGTTISDTR IPGVWGPFDT ILDNRGDFSV 310 320 330 340 350 360 YAAGQSCTGK LIEHLFESHP CARKILKDGA DIYQVLEQTI RDIEKNNGLS IHILTKDMFF 370 380 390 400 410 420 YGDYEGNRTP FADPRIKGSF IGESTDTSML NLTYKYICIL EFLSFQTKLI IDTFQNENSN 430 440 450 460 470 480 IHIKELRISG SQAKNERLLS LISLVNNGVA IIKPKENVDM MGIKGAYVLA KSAKEKKQLA 490 500 510 520 530 540 DVITERDISN DSEKFESLAE YRLGNDSILL RKLLCVKYHI HLDMAKQQKR YHKLVDEVFQ HL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence analysis of the 33 kb long region between ORC5 and SUI1 from the left arm of chromosome XIV from Saccharomyces cerevisiae." Sen-Gupta M., Gueldener U., Beinhauer J.D., Fiedler T.A., Hegemann J.H. Yeast 13:849-860(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[2]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications." Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., Beinhauer J.D., Boskovic J., Buitrago M.J. , Bussereau F., Coster F., Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J. Nature 387:93-98(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[3]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[4]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[5]	Boles E., Hettmann C., Zimmermann F.K. Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 41-542. Strain: ENY.WA-1A.
[6]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X96722 Genomic DNA. Translation: CAA65495.1. Z71525 Genomic DNA. Translation: CAA96156.1. AY723861 Genomic DNA. Translation: AAU09778.1. X94214 Genomic DNA. Translation: CAA63905.1. BK006947 Genomic DNA. Translation: DAA10310.1.
PIR	S63222.
RefSeq	NP_014150.1. NM_001183087.1.
3D structure databases
ProteinModelPortal	P53583.
ModBase	Search...
Protein-protein interaction databases
IntAct	P53583. 24 interactions.
STRING	4932.YNL249C.
Proteomic databases
PaxDb	P53583.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YNL249C; YNL249C; YNL249C.
GeneID	855472.
KEGG	sce:YNL249C.
Organism-specific databases
CYGD	YNL249c.
SGD	S000005193. MPA43.
Phylogenomic databases
eggNOG	COG1069.
HOGENOM	HOG000057114.
OMA	CFELYDW.
OrthoDB	EOG4MKRR9.
Gene expression databases
Genevestigator	P53583.
GermOnline	YNL249C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR018485. Carb_kinase_FGGY_C. IPR018484. Carb_kinase_FGGY_N. [Graphical view]
Pfam	PF02782. FGGY_C. 1 hit. PF00370. FGGY_N. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	979421.

Entry information

Entry name

MPA43_YEAST

Accession

Primary (citable) accession number: P53583
Secondary accession number(s): D6W0U4

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	April 3, 2013
This is version 80 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program