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Protein

Actin-11

Gene

ACT11

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth. This is considered as one of the reproductive actins.

GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • structural constituent of cytoskeleton Source: TAIR
Complete GO annotation...

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Actin-11
Gene namesi
Name:ACT11
Ordered Locus Names:At3g12110
ORF Names:T21B14.7, T21B14_108, T23B7.5
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

TAIRiAT3G12110.

Subcellular locationi

GO - Cellular componenti

  • chloroplast envelope Source: TAIR
  • chloroplast stroma Source: TAIR
  • cytoskeleton Source: TAIR
  • mitochondrion Source: TAIR
  • plasma membrane Source: TAIR
  • plasmodesma Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 377376Actin-11PRO_0000088895Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanineBy similarity

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiP53496.
PRIDEiP53496.

PTM databases

iPTMnetiP53496.

Expressioni

Tissue specificityi

Preferentially expressed in young and expanding tissues, floral organ primordia, developing seeds, and emerging inflorescence. Displays a very high expression level in mature pollen and pollen tubes. Little or no reproductive-gene expression is detected in vegetative organs, such as root, stems, leaves, sepals and petals.

Developmental stagei

Significantly expressed during endosperm, ovule and embryo development.

Gene expression databases

ExpressionAtlasiP53496. baseline and differential.
GenevisibleiP53496. AT.

Interactioni

Subunit structurei

Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. The binding of profilin to monomeric G-actin cause the sequestration of actin into profilactin complexes, and prevents the polymerization.

Protein-protein interaction databases

BioGridi5719. 7 interactions.
IntActiP53496. 5 interactions.
STRINGi3702.AT3G12110.1.

Structurei

3D structure databases

ProteinModelPortaliP53496.
SMRiP53496. Positions 10-377.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the actin family.Curated

Phylogenomic databases

eggNOGiKOG0676. Eukaryota.
COG5277. LUCA.
HOGENOMiHOG000233340.
InParanoidiP53496.
KOiK10355.
OMAiAMCEEED.
OrthoDBiEOG09360BTG.
PhylomeDBiP53496.

Family and domain databases

InterProiIPR004000. Actin.
IPR020902. Actin/actin-like_CS.
IPR004001. Actin_CS.
[Graphical view]
PANTHERiPTHR11937. PTHR11937. 1 hit.
PfamiPF00022. Actin. 1 hit.
[Graphical view]
PRINTSiPR00190. ACTIN.
SMARTiSM00268. ACTIN. 1 hit.
[Graphical view]
PROSITEiPS00406. ACTINS_1. 1 hit.
PS00432. ACTINS_2. 1 hit.
PS01132. ACTINS_ACT_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P53496-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADGEDIQPL VCDNGTGMVK AGFAGDDAPR AVFPSIVGRP RHTGVMVGMG
60 70 80 90 100
QKDAYVGDEA QSKRGILTLK YPIEHGIVSN WDDMEKIWHH TFYNELRVAP
110 120 130 140 150
EEHPVLLTEA PLNPKANREK MTQIMFETFN TPAMYVAIQA VLSLYASGRT
160 170 180 190 200
TGIVLDSGDG VSHTVPIYEG YALPHAILRL DLAGRDLTDY LMKILTERGY
210 220 230 240 250
SFTTSAEREI VRDVKEKLAY IALDYEQEME TANTSSSVEK SYELPDGQVI
260 270 280 290 300
TIGGERFRCP EVLFQPSLVG MEAAGIHETT YNSIMKCDVD IRKDLYGNIV
310 320 330 340 350
LSGGTTMFPG IADRMSKEIT ALAPSSMKIK VVAPPERKYS VWIGGSILAS
360 370
LSTFQQMWIA KAEYDESGPS IVHRKCF
Length:377
Mass (Da):41,675
Last modified:October 1, 1996 - v1
Checksum:i93BAA4D67DA3EE61
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U27981 Genomic DNA. Translation: AAB39404.1.
AC069473 Genomic DNA. Translation: AAG51045.1.
AP002063 Genomic DNA. Translation: BAB01959.1.
CP002686 Genomic DNA. Translation: AEE75151.1.
BT005593 mRNA. Translation: AAO64013.1.
AY087740 mRNA. Translation: AAM65277.1.
PIRiS68109.
RefSeqiNP_187818.1. NM_112046.3.
UniGeneiAt.28138.

Genome annotation databases

EnsemblPlantsiAT3G12110.1; AT3G12110.1; AT3G12110.
GeneIDi820385.
GrameneiAT3G12110.1; AT3G12110.1; AT3G12110.
KEGGiath:AT3G12110.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U27981 Genomic DNA. Translation: AAB39404.1.
AC069473 Genomic DNA. Translation: AAG51045.1.
AP002063 Genomic DNA. Translation: BAB01959.1.
CP002686 Genomic DNA. Translation: AEE75151.1.
BT005593 mRNA. Translation: AAO64013.1.
AY087740 mRNA. Translation: AAM65277.1.
PIRiS68109.
RefSeqiNP_187818.1. NM_112046.3.
UniGeneiAt.28138.

3D structure databases

ProteinModelPortaliP53496.
SMRiP53496. Positions 10-377.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi5719. 7 interactions.
IntActiP53496. 5 interactions.
STRINGi3702.AT3G12110.1.

PTM databases

iPTMnetiP53496.

Proteomic databases

PaxDbiP53496.
PRIDEiP53496.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G12110.1; AT3G12110.1; AT3G12110.
GeneIDi820385.
GrameneiAT3G12110.1; AT3G12110.1; AT3G12110.
KEGGiath:AT3G12110.

Organism-specific databases

TAIRiAT3G12110.

Phylogenomic databases

eggNOGiKOG0676. Eukaryota.
COG5277. LUCA.
HOGENOMiHOG000233340.
InParanoidiP53496.
KOiK10355.
OMAiAMCEEED.
OrthoDBiEOG09360BTG.
PhylomeDBiP53496.

Miscellaneous databases

PROiP53496.

Gene expression databases

ExpressionAtlasiP53496. baseline and differential.
GenevisibleiP53496. AT.

Family and domain databases

InterProiIPR004000. Actin.
IPR020902. Actin/actin-like_CS.
IPR004001. Actin_CS.
[Graphical view]
PANTHERiPTHR11937. PTHR11937. 1 hit.
PfamiPF00022. Actin. 1 hit.
[Graphical view]
PRINTSiPR00190. ACTIN.
SMARTiSM00268. ACTIN. 1 hit.
[Graphical view]
PROSITEiPS00406. ACTINS_1. 1 hit.
PS00432. ACTINS_2. 1 hit.
PS01132. ACTINS_ACT_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiACT11_ARATH
AccessioniPrimary (citable) accession number: P53496
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: September 7, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Miscellaneous

There are 8 actin genes in A.thaliana.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.