Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glycerol-3-phosphate dehydrogenase

Gene

glpD

Organism
Mycobacterium leprae (strain TN)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.

Cofactori

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi37 – 6529FADBy similarityAdd
BLAST

GO - Molecular functioni

  1. sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycerol-3-phosphate metabolic process Source: InterPro
  2. glycerol metabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Glycerol metabolism

Keywords - Ligandi

FAD, Flavoprotein

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase (EC:1.1.5.3)
Gene namesi
Name:glpD
Ordered Locus Names:ML0713
ORF Names:L308_C1_179
OrganismiMycobacterium leprae (strain TN)
Taxonomic identifieri272631 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000000806: Chromosome

Organism-specific databases

LepromaiML0713.

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. glycerol-3-phosphate dehydrogenase complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 585585Glycerol-3-phosphate dehydrogenasePRO_0000126099Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272631.ML0713.

Structurei

3D structure databases

ProteinModelPortaliP53435.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0578.
HOGENOMiHOG000004813.
KOiK00111.
OMAiPVDQQEQ.
OrthoDBiEOG651SR7.

Family and domain databases

InterProiIPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
PROSITEiPS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P53435-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDLIQAPES EQTWPASALG PQQRAAAWER FGTEQFDVVV IGGGVVGSGC
60 70 80 90 100
ALDAATRGLK VALVEARDLA SGTSSRSSKM FHGGLRYLEQ LEFGLVREAL
110 120 130 140 150
YERELSLTTL APHLVKPLPF LFPLTKRWWE RPYIAAGIFL YDRLGGAKSV
160 170 180 190 200
PAQKHLTRAG ALRLSPGLKR SSLIGGIRYY DTVVDDARHT LTVARTAAHY
210 220 230 240 250
GAVVRCSTQV VALLREGDRV IGVRVRDSED GAVTEIRGHV VVNATGVWTD
260 270 280 290 300
EIQALSKQRG RFQVRVSKGV HVVVPRDRIV SDVAMILRTK KSVMFIIPWG
310 320 330 340 350
NHWIIGTTDT DWNLDLAHPA ATKADIDYIL QTVNTVLATP LTHADIDGVY
360 370 380 390 400
AGLRPLLAGE SDDTSKLTRE HAVAVPVAGL VAIAGGKYTT YRVMAADAID
410 420 430 440 450
AAVAFVPARV APSITEKVGL LGADGYFALI NQVEHVAALQ GLHPYRVRHL
460 470 480 490 500
LDRYGALIGD VLALAAEAPD LLSPIQEAPG YLKVEARYAV TAEGALHLED
510 520 530 540 550
ILARRMRVSI EYPHRGVACA REVADVVAPV LGWTAEDIDR EVATYNARVE
560 570 580
AEVLSQAQPD DVSADMLRAS APEARTKIIE PVSLT
Length:585
Mass (Da):63,373
Last modified:October 1, 1996 - v1
Checksum:i4B468DD09C1C70F8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00022 Genomic DNA. Translation: AAA17328.1.
AL583919 Genomic DNA. Translation: CAC30222.1.
PIRiS73029.
RefSeqiNP_301564.1. NC_002677.1.
WP_010907888.1. NC_002677.1.

Genome annotation databases

EnsemblBacteriaiCAC30222; CAC30222; CAC30222.
GeneIDi909648.
KEGGimle:ML0713.
PATRICi18052682. VBIMycLep78757_1287.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00022 Genomic DNA. Translation: AAA17328.1.
AL583919 Genomic DNA. Translation: CAC30222.1.
PIRiS73029.
RefSeqiNP_301564.1. NC_002677.1.
WP_010907888.1. NC_002677.1.

3D structure databases

ProteinModelPortaliP53435.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272631.ML0713.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAC30222; CAC30222; CAC30222.
GeneIDi909648.
KEGGimle:ML0713.
PATRICi18052682. VBIMycLep78757_1287.

Organism-specific databases

LepromaiML0713.

Phylogenomic databases

eggNOGiCOG0578.
HOGENOMiHOG000004813.
KOiK00111.
OMAiPVDQQEQ.
OrthoDBiEOG651SR7.

Family and domain databases

InterProiIPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
PROSITEiPS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Smith D.R., Robison K.
    Submitted (MAR-1994) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TN.

Entry informationi

Entry nameiGLPD_MYCLE
AccessioniPrimary (citable) accession number: P53435
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: January 7, 2015
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.