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P53435

- GLPD_MYCLE

UniProt

P53435 - GLPD_MYCLE

Protein

Glycerol-3-phosphate dehydrogenase

Gene

glpD

Organism
Mycobacterium leprae (strain TN)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 89 (01 Oct 2014)
      Sequence version 1 (01 Oct 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.

    Cofactori

    FAD.

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi37 – 6529FADBy similarityAdd
    BLAST

    GO - Molecular functioni

    1. sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glycerol-3-phosphate metabolic process Source: InterPro
    2. glycerol metabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Glycerol metabolism

    Keywords - Ligandi

    FAD, Flavoprotein

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glycerol-3-phosphate dehydrogenase (EC:1.1.5.3)
    Gene namesi
    Name:glpD
    Ordered Locus Names:ML0713
    ORF Names:L308_C1_179
    OrganismiMycobacterium leprae (strain TN)
    Taxonomic identifieri272631 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
    ProteomesiUP000000806: Chromosome

    Organism-specific databases

    LepromaiML0713.

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. glycerol-3-phosphate dehydrogenase complex Source: InterPro

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 585585Glycerol-3-phosphate dehydrogenasePRO_0000126099Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272631.ML0713.

    Structurei

    3D structure databases

    ProteinModelPortaliP53435.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0578.
    HOGENOMiHOG000004813.
    KOiK00111.
    OMAiYAKVDSF.
    OrthoDBiEOG651SR7.

    Family and domain databases

    InterProiIPR006076. FAD-dep_OxRdtase.
    IPR000447. G3P_DH_FAD-dep.
    [Graphical view]
    PfamiPF01266. DAO. 1 hit.
    [Graphical view]
    PRINTSiPR01001. FADG3PDH.
    PROSITEiPS00977. FAD_G3PDH_1. 1 hit.
    PS00978. FAD_G3PDH_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P53435-1 [UniParc]FASTAAdd to Basket

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    MTDLIQAPES EQTWPASALG PQQRAAAWER FGTEQFDVVV IGGGVVGSGC    50
    ALDAATRGLK VALVEARDLA SGTSSRSSKM FHGGLRYLEQ LEFGLVREAL 100
    YERELSLTTL APHLVKPLPF LFPLTKRWWE RPYIAAGIFL YDRLGGAKSV 150
    PAQKHLTRAG ALRLSPGLKR SSLIGGIRYY DTVVDDARHT LTVARTAAHY 200
    GAVVRCSTQV VALLREGDRV IGVRVRDSED GAVTEIRGHV VVNATGVWTD 250
    EIQALSKQRG RFQVRVSKGV HVVVPRDRIV SDVAMILRTK KSVMFIIPWG 300
    NHWIIGTTDT DWNLDLAHPA ATKADIDYIL QTVNTVLATP LTHADIDGVY 350
    AGLRPLLAGE SDDTSKLTRE HAVAVPVAGL VAIAGGKYTT YRVMAADAID 400
    AAVAFVPARV APSITEKVGL LGADGYFALI NQVEHVAALQ GLHPYRVRHL 450
    LDRYGALIGD VLALAAEAPD LLSPIQEAPG YLKVEARYAV TAEGALHLED 500
    ILARRMRVSI EYPHRGVACA REVADVVAPV LGWTAEDIDR EVATYNARVE 550
    AEVLSQAQPD DVSADMLRAS APEARTKIIE PVSLT 585
    Length:585
    Mass (Da):63,373
    Last modified:October 1, 1996 - v1
    Checksum:i4B468DD09C1C70F8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00022 Genomic DNA. Translation: AAA17328.1.
    AL583919 Genomic DNA. Translation: CAC30222.1.
    PIRiS73029.
    RefSeqiNP_301564.1. NC_002677.1.
    WP_010907888.1. NC_002677.1.

    Genome annotation databases

    EnsemblBacteriaiCAC30222; CAC30222; CAC30222.
    GeneIDi909648.
    KEGGimle:ML0713.
    PATRICi18052682. VBIMycLep78757_1287.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00022 Genomic DNA. Translation: AAA17328.1 .
    AL583919 Genomic DNA. Translation: CAC30222.1 .
    PIRi S73029.
    RefSeqi NP_301564.1. NC_002677.1.
    WP_010907888.1. NC_002677.1.

    3D structure databases

    ProteinModelPortali P53435.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272631.ML0713.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAC30222 ; CAC30222 ; CAC30222 .
    GeneIDi 909648.
    KEGGi mle:ML0713.
    PATRICi 18052682. VBIMycLep78757_1287.

    Organism-specific databases

    Lepromai ML0713.

    Phylogenomic databases

    eggNOGi COG0578.
    HOGENOMi HOG000004813.
    KOi K00111.
    OMAi YAKVDSF.
    OrthoDBi EOG651SR7.

    Family and domain databases

    InterProi IPR006076. FAD-dep_OxRdtase.
    IPR000447. G3P_DH_FAD-dep.
    [Graphical view ]
    Pfami PF01266. DAO. 1 hit.
    [Graphical view ]
    PRINTSi PR01001. FADG3PDH.
    PROSITEi PS00977. FAD_G3PDH_1. 1 hit.
    PS00978. FAD_G3PDH_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Smith D.R., Robison K.
      Submitted (MAR-1994) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TN.

    Entry informationi

    Entry nameiGLPD_MYCLE
    AccessioniPrimary (citable) accession number: P53435
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: October 1, 1996
    Last modified: October 1, 2014
    This is version 89 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3