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P53435 (GLPD_MYCLE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 87. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycerol-3-phosphate dehydrogenase

EC=1.1.5.3
Gene names
Name:glpD
Ordered Locus Names:ML0713
ORF Names:L308_C1_179
OrganismMycobacterium leprae (strain TN) [Complete proteome] [HAMAP]
Taxonomic identifier272631 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium

Protein attributes

Sequence length585 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.

Cofactor

FAD.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

Ontologies

Keywords
   Biological processGlycerol metabolism
   Cellular componentCytoplasm
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycerol metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

glycerol-3-phosphate metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentglycerol-3-phosphate dehydrogenase complex

Inferred from electronic annotation. Source: InterPro

   Molecular_functionsn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 585585Glycerol-3-phosphate dehydrogenase
PRO_0000126099

Regions

Nucleotide binding37 – 6529FAD By similarity

Sequences

Sequence LengthMass (Da)Tools
P53435 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: 4B468DD09C1C70F8

FASTA58563,373
        10         20         30         40         50         60 
MTDLIQAPES EQTWPASALG PQQRAAAWER FGTEQFDVVV IGGGVVGSGC ALDAATRGLK 

        70         80         90        100        110        120 
VALVEARDLA SGTSSRSSKM FHGGLRYLEQ LEFGLVREAL YERELSLTTL APHLVKPLPF 

       130        140        150        160        170        180 
LFPLTKRWWE RPYIAAGIFL YDRLGGAKSV PAQKHLTRAG ALRLSPGLKR SSLIGGIRYY 

       190        200        210        220        230        240 
DTVVDDARHT LTVARTAAHY GAVVRCSTQV VALLREGDRV IGVRVRDSED GAVTEIRGHV 

       250        260        270        280        290        300 
VVNATGVWTD EIQALSKQRG RFQVRVSKGV HVVVPRDRIV SDVAMILRTK KSVMFIIPWG 

       310        320        330        340        350        360 
NHWIIGTTDT DWNLDLAHPA ATKADIDYIL QTVNTVLATP LTHADIDGVY AGLRPLLAGE 

       370        380        390        400        410        420 
SDDTSKLTRE HAVAVPVAGL VAIAGGKYTT YRVMAADAID AAVAFVPARV APSITEKVGL 

       430        440        450        460        470        480 
LGADGYFALI NQVEHVAALQ GLHPYRVRHL LDRYGALIGD VLALAAEAPD LLSPIQEAPG 

       490        500        510        520        530        540 
YLKVEARYAV TAEGALHLED ILARRMRVSI EYPHRGVACA REVADVVAPV LGWTAEDIDR 

       550        560        570        580 
EVATYNARVE AEVLSQAQPD DVSADMLRAS APEARTKIIE PVSLT 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00022 Genomic DNA. Translation: AAA17328.1.
AL583919 Genomic DNA. Translation: CAC30222.1.
PIRS73029.
RefSeqNP_301564.1. NC_002677.1.

3D structure databases

ProteinModelPortalP53435.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272631.ML0713.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAC30222; CAC30222; CAC30222.
GeneID909648.
KEGGmle:ML0713.
PATRIC18052682. VBIMycLep78757_1287.

Organism-specific databases

LepromaML0713.
CMRSearch...

Phylogenomic databases

eggNOGCOG0578.
HOGENOMHOG000004813.
KOK00111.
OMAYAKVDSF.
OrthoDBEOG651SR7.

Family and domain databases

InterProIPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
PfamPF01266. DAO. 1 hit.
[Graphical view]
PRINTSPR01001. FADG3PDH.
PROSITEPS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGLPD_MYCLE
AccessionPrimary (citable) accession number: P53435
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 14, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families