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P53415

- CHS2_SECCE

UniProt

P53415 - CHS2_SECCE

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Protein

Chalcone synthase 2

Gene
CHS2
Organism
Secale cereale (Rye)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activityi

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei167 – 1671 By similarity

GO - Molecular functioni

  1. naringenin-chalcone synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. flavonoid biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Flavonoid biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00154.

Names & Taxonomyi

Protein namesi
Recommended name:
Chalcone synthase 2 (EC:2.3.1.74)
Alternative name(s):
Naringenin-chalcone synthase 2
Gene namesi
Name:CHS2
OrganismiSecale cereale (Rye)
Taxonomic identifieri4550 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladePooideaeTriticeaeSecale

Organism-specific databases

GrameneiP53415.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 394394Chalcone synthase 2PRO_0000216049Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP53415.
SMRiP53415. Positions 6-392.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.40.47.10. 2 hits.
InterProiIPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamiPF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000451. PKS_III. 1 hit.
SUPFAMiSSF53901. SSF53901. 2 hits.
PROSITEiPS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P53415-1 [UniParc]FASTAAdd to Basket

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MAATMTVEEV RKAQRAEGPA TVLAIGTATP ANCVYQADYP DYYFKITKSD    50
HMADLKEKFK RMCDKSQIRK RYMHLTEEIL QDNPNMCAYM APSLDARQDI 100
VVVEVPKLGK AAAQKAIKEW GQPRSKITHL VFCTTSGVDM PGADYQLTKM 150
LGLRPSVKRL MMYQQGCFAG GTVLRLAKDL AENNRGARVL VVCSEITAVT 200
FRGPHESHLD SLVGQALFGD GAAAVIIGAD PDESIERPLF QLVSASQTIL 250
PDSEGAIDGH LREVGLTFHL LKDVPGLISK NIERALEDAF KPLGIDDWNS 300
VFWIAHPGGP AILDMVEAKV NLNKERMRAT RHVLSEYGNM SSACVLFIMD 350
EMRKRSAEDG HTTTGEGMDW GVLFGFGPGL TVETVVLHSV PVTA 394
Length:394
Mass (Da):43,224
Last modified:October 1, 1996 - v1
Checksum:i56A44FF0BD457B1F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X92547 mRNA. Translation: CAA63305.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X92547 mRNA. Translation: CAA63305.1 .

3D structure databases

ProteinModelPortali P53415.
SMRi P53415. Positions 6-392.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

Gramenei P53415.

Enzyme and pathway databases

UniPathwayi UPA00154 .

Family and domain databases

Gene3Di 3.40.47.10. 2 hits.
InterProi IPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view ]
Pfami PF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000451. PKS_III. 1 hit.
SUPFAMi SSF53901. SSF53901. 2 hits.
PROSITEi PS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Expression of chalcone synthase genes in coleoptiles and primary leaves of Secale cereale L. after induction by UV radiation: evidence for a UV-protective role of the coleoptile."
    Haussuehl K.K., Rohde W., Weissenboeck G.
    Bot. Acta 109:229-238(1996)
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Kustro.

Entry informationi

Entry nameiCHS2_SECCE
AccessioniPrimary (citable) accession number: P53415
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: October 16, 2013
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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