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Protein

Putative sulfate transporter YPR003C

Gene

YPR003C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Possible sulfate transporter.

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciYEAST:G3O-34165-MONOMER.
ReactomeiR-SCE-174362. Transport and synthesis of PAPS.
R-SCE-427601. Multifunctional anion exchangers.

Protein family/group databases

TCDBi2.A.53.1.11. the sulfate permease (sulp) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative sulfate transporter YPR003C
Gene namesi
Ordered Locus Names:YPR003C
ORF Names:LPZ3C, YP9723.03C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XVI

Organism-specific databases

EuPathDBiFungiDB:YPR003C.
SGDiS000006207. YPR003C.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 118CytoplasmicSequence analysisAdd BLAST118
Transmembranei119 – 139HelicalSequence analysisAdd BLAST21
Topological domaini140 – 146LumenalSequence analysis7
Transmembranei147 – 167HelicalSequence analysisAdd BLAST21
Topological domaini168 – 172CytoplasmicSequence analysis5
Transmembranei173 – 193HelicalSequence analysisAdd BLAST21
Topological domaini194 – 199LumenalSequence analysis6
Transmembranei200 – 220HelicalSequence analysisAdd BLAST21
Topological domaini221 – 232CytoplasmicSequence analysisAdd BLAST12
Transmembranei233 – 253HelicalSequence analysisAdd BLAST21
Topological domaini254 – 282LumenalSequence analysisAdd BLAST29
Transmembranei283 – 303HelicalSequence analysisAdd BLAST21
Topological domaini304 – 317CytoplasmicSequence analysisAdd BLAST14
Transmembranei318 – 338HelicalSequence analysisAdd BLAST21
Topological domaini339 – 370LumenalSequence analysisAdd BLAST32
Transmembranei371 – 391HelicalSequence analysisAdd BLAST21
Topological domaini392 – 410CytoplasmicSequence analysisAdd BLAST19
Transmembranei411 – 431HelicalSequence analysisAdd BLAST21
Topological domaini432 – 450LumenalSequence analysisAdd BLAST19
Transmembranei451 – 471HelicalSequence analysisAdd BLAST21
Topological domaini472 – 474CytoplasmicSequence analysis3
Transmembranei475 – 495HelicalSequence analysisAdd BLAST21
Topological domaini496 – 517LumenalSequence analysisAdd BLAST22
Transmembranei518 – 538HelicalSequence analysisAdd BLAST21
Topological domaini539 – 754CytoplasmicSequence analysisAdd BLAST216

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000801921 – 754Putative sulfate transporter YPR003CAdd BLAST754

Proteomic databases

PRIDEiP53394.

PTM databases

iPTMnetiP53394.

Interactioni

Protein-protein interaction databases

BioGridi36180. 21 interactors.
DIPiDIP-5055N.
IntActiP53394. 2 interactors.
MINTiMINT-488059.

Structurei

3D structure databases

ProteinModelPortaliP53394.
SMRiP53394.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini574 – 725STASPROSITE-ProRule annotationAdd BLAST152

Sequence similaritiesi

Contains 1 STAS domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00760000119026.
HOGENOMiHOG000199477.
InParanoidiP53394.
OrthoDBiEOG092C0S9J.

Family and domain databases

Gene3Di3.30.750.24. 1 hit.
InterProiIPR018045. S04_transporter_CS.
IPR011547. SLC26A/SulP_dom.
IPR001902. SLC26A/SulP_fam.
IPR002645. STAS_dom.
[Graphical view]
PANTHERiPTHR11814. PTHR11814. 2 hits.
PfamiPF01740. STAS. 1 hit.
PF00916. Sulfate_transp. 1 hit.
[Graphical view]
SUPFAMiSSF52091. SSF52091. 1 hit.
PROSITEiPS01130. SLC26A. 1 hit.
PS50801. STAS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P53394-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSNNSLLGR GRMSYSSTAP PRFKRSVDQR DTFSDNFDYD KDSSNRGRTY
60 70 80 90 100
IAASNSTTGV PPPNNSRSGC TNNTNNTNNT SNTSNTNNND SVDENTVFET
110 120 130 140 150
LPYYLPCFSW LPEYTFNKLW GDVIAGISVA SFQIPLALSY TTSIAHVPPL
160 170 180 190 200
CGLYSLAISP FVYGILGSVP QMIVGPESAI SLVVGQAVES ITLHKENVSL
210 220 230 240 250
IDISTVITFV SGTILLFSGI SRFGFLGNVL SKALLRGFIS SVGLVMIINS
260 270 280 290 300
LISELKLDKF LVSLPQHYHT PFEKILFLID YAPAQYHIPT AIFSGCCLIV
310 320 330 340 350
LFLTRLLKRK LMKYHKSAIF FPDILLVVIV TILISMKFNL KHRYGISIIG
360 370 380 390 400
DFSMDNFDEL KNPLTRPRRK LIPDLFSASL IVAMLGFFES TTASKSLGTT
410 420 430 440 450
YNLTVSSNRE LVALGFMNIV ISLFGALPAF GGYGRSKINA LSGAQSVMSG
460 470 480 490 500
VFMGVITLIT MNLLLQFVHY IPNCVLSVIT TIIGISLLEE VPGDIKFHLR
510 520 530 540 550
CGGFSELFVF AVTFCTTIFY SIEAGICIGC VYSIINIIKH SAKSRIQILA
560 570 580 590 600
RVAGTSNFTN LDDYMMNMKR NSLDVEGTEE IEGCMIVRIP EPLTFTNSED
610 620 630 640 650
LKQRLDRIER YGSSKIHPGR KSLRSKDSIK YVIFDLGGMT SIDSSAAQVL
660 670 680 690 700
EEIITSYKRR NVFIYLVNVS INDKVRRRLF KAGVAASVER AQANNNENNT
710 720 730 740 750
SNTFSDAGET YSPYFDSIDA ALYEIEKMKI KGNNVPNNDS ESFMSNTLFN

SSLV
Length:754
Mass (Da):83,384
Last modified:October 1, 1996 - v1
Checksum:i4558DA8B79803E6E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z71255 Genomic DNA. Translation: CAA95043.1.
U31900 Genomic DNA. Translation: AAA97582.1.
Z48951 Genomic DNA. Translation: CAA88781.1.
BK006949 Genomic DNA. Translation: DAA11430.1.
PIRiS52816.
RefSeqiNP_015328.1. NM_001184100.1.

Genome annotation databases

EnsemblFungiiYPR003C; YPR003C; YPR003C.
GeneIDi856111.
KEGGisce:YPR003C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z71255 Genomic DNA. Translation: CAA95043.1.
U31900 Genomic DNA. Translation: AAA97582.1.
Z48951 Genomic DNA. Translation: CAA88781.1.
BK006949 Genomic DNA. Translation: DAA11430.1.
PIRiS52816.
RefSeqiNP_015328.1. NM_001184100.1.

3D structure databases

ProteinModelPortaliP53394.
SMRiP53394.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi36180. 21 interactors.
DIPiDIP-5055N.
IntActiP53394. 2 interactors.
MINTiMINT-488059.

Protein family/group databases

TCDBi2.A.53.1.11. the sulfate permease (sulp) family.

PTM databases

iPTMnetiP53394.

Proteomic databases

PRIDEiP53394.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYPR003C; YPR003C; YPR003C.
GeneIDi856111.
KEGGisce:YPR003C.

Organism-specific databases

EuPathDBiFungiDB:YPR003C.
SGDiS000006207. YPR003C.

Phylogenomic databases

GeneTreeiENSGT00760000119026.
HOGENOMiHOG000199477.
InParanoidiP53394.
OrthoDBiEOG092C0S9J.

Enzyme and pathway databases

BioCyciYEAST:G3O-34165-MONOMER.
ReactomeiR-SCE-174362. Transport and synthesis of PAPS.
R-SCE-427601. Multifunctional anion exchangers.

Miscellaneous databases

PROiP53394.

Family and domain databases

Gene3Di3.30.750.24. 1 hit.
InterProiIPR018045. S04_transporter_CS.
IPR011547. SLC26A/SulP_dom.
IPR001902. SLC26A/SulP_fam.
IPR002645. STAS_dom.
[Graphical view]
PANTHERiPTHR11814. PTHR11814. 2 hits.
PfamiPF01740. STAS. 1 hit.
PF00916. Sulfate_transp. 1 hit.
[Graphical view]
SUPFAMiSSF52091. SSF52091. 1 hit.
PROSITEiPS01130. SLC26A. 1 hit.
PS50801. STAS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSULX_YEAST
AccessioniPrimary (citable) accession number: P53394
Secondary accession number(s): D6W414
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: November 30, 2016
This is version 132 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XVI
    Yeast (Saccharomyces cerevisiae) chromosome XVI: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.