P53343 (PAU12_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Seripauperin-12

Gene names

Name:	PAU12
Ordered Locus Names:	YGR294W

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	120 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Membrane; Single-pass membrane protein Potential.
Sequence similarities	Belongs to the SRP1/TIP1 family. Seripauperin subfamily.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	response to stress Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 120	120	Seripauperin-12		PRO_0000203786
Regions
	Transmembrane	7 – 24	18	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	P53343 [UniParc]. Last modified October 1, 1996. Version 1. Checksum: 07C3859D2A7480CC	FASTA	120	12,820
	10 20 30 40 50 60 MVKLTSIAAG VAAIAATASA TTTLAQSDER VNLVELGVYV SDIRAHLAQY YSFQAAHPTE 70 80 90 100 110 120 TYPVEIAEAV FNYGDFTTML TGIAPDQVTR MITGVPWYSS RLKPAISSAL SKDGIYTIAN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome VII." Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E. , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K. Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 96604 / S288c / FY1679.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z73078 Genomic DNA. Translation: CAA97327.1. BK006941 Genomic DNA. Translation: DAA08379.1.
PIR	S64631.
RefSeq	NP_011810.1. NM_001181423.1.
3D structure databases
ProteinModelPortal	P53343.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-1871N.
IntAct	P53343. 3 interactions.
MINT	MINT-404918.
STRING	4932.YGR294W.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YGR294W; YGR294W; YGR294W.
GeneID	853210.
KEGG	sce:YGR294W.
Organism-specific databases
CYGD	YGR294w.
SGD	S000003526. PAU12.
Phylogenomic databases
GeneTree	ENSGT00530000064578.
HOGENOM	HOG000000707.
OrthoDB	EOG4WT0MF.
Gene expression databases
Genevestigator	P53343.
GermOnline	YGR294W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR000992. SRP1_TIP1. [Graphical view]
Pfam	PF00660. SRP1_TIP1. 1 hit. [Graphical view]
PROSITE	PS00724. SRP1_TIP1. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	973395.

Entry information

Entry name

PAU12_YEAST

Accession

Primary (citable) accession number: P53343
Secondary accession number(s): D6VV68

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1996
Last sequence update:	October 1, 1996
Last modified:	April 3, 2013
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program