ID   YG5L_YEAST              Reviewed;         701 AA.
AC   P53326; D6VV44;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   27-MAR-2024, entry version 140.
DE   RecName: Full=Uncharacterized protein YGR266W;
GN   OrderedLocusNames=YGR266W;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 96604 / S288c / FY1679;
RX   PubMed=9605509;
RX   DOI=10.1002/(sici)1097-0061(19980430)14:6<587::aid-yea268>3.0.co;2-i;
RA   Agostoni Carbone M.L., Lucchini G., Melchioretto P., Nardese V., Vanoni M.,
RA   Panzeri L.;
RT   "A 9359 bp fragment from the right arm of Saccharomyces cerevisiae
RT   chromosome VII includes the FOL2 and YTA7 genes and three unknown open
RT   reading frames.";
RL   Yeast 14:587-591(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169869;
RA   Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J.,
RA   Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M.,
RA   Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L.,
RA   Coblenz A., Coglievina M., Coissac E., Defoor E., Del Bino S., Delius H.,
RA   Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P.,
RA   Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M.,
RA   Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A.,
RA   Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K.,
RA   Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P.,
RA   Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E.,
RA   Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K.,
RA   Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A.,
RA   Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S.,
RA   Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M.,
RA   Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C.,
RA   Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M.,
RA   Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M.,
RA   Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y.,
RA   Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L.,
RA   Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D.,
RA   Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F.,
RA   Zaccaria P., Zimmermann M., Zollner A., Kleine K.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.";
RL   Nature 387:81-84(1997).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [4]
RP   LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX   PubMed=14562106; DOI=10.1038/nature02046;
RA   Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA   O'Shea E.K., Weissman J.S.;
RT   "Global analysis of protein expression in yeast.";
RL   Nature 425:737-741(2003).
RN   [5]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=19779198; DOI=10.1126/science.1172867;
RA   Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.;
RT   "Global analysis of Cdk1 substrate phosphorylation sites provides insights
RT   into evolution.";
RL   Science 325:1682-1686(2009).
CC   -!- MISCELLANEOUS: Present with 3230 molecules/cell in log phase SD medium.
CC       {ECO:0000269|PubMed:14562106}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; Y07893; CAA69197.1; -; Genomic_DNA.
DR   EMBL; Z73051; CAA97296.1; -; Genomic_DNA.
DR   EMBL; BK006941; DAA08355.1; -; Genomic_DNA.
DR   PIR; S64599; S64599.
DR   RefSeq; NP_011782.1; NM_001181395.1.
DR   AlphaFoldDB; P53326; -.
DR   BioGRID; 33516; 61.
DR   DIP; DIP-6585N; -.
DR   IntAct; P53326; 6.
DR   MINT; P53326; -.
DR   STRING; 4932.YGR266W; -.
DR   iPTMnet; P53326; -.
DR   MaxQB; P53326; -.
DR   PaxDb; 4932-YGR266W; -.
DR   PeptideAtlas; P53326; -.
DR   EnsemblFungi; YGR266W_mRNA; YGR266W; YGR266W.
DR   GeneID; 853182; -.
DR   KEGG; sce:YGR266W; -.
DR   AGR; SGD:S000003498; -.
DR   SGD; S000003498; YGR266W.
DR   VEuPathDB; FungiDB:YGR266W; -.
DR   eggNOG; ENOG502QPI0; Eukaryota.
DR   HOGENOM; CLU_000998_3_0_1; -.
DR   InParanoid; P53326; -.
DR   OMA; GPNLWND; -.
DR   OrthoDB; 1385369at2759; -.
DR   BioCyc; YEAST:G3O-30934-MONOMER; -.
DR   BioGRID-ORCS; 853182; 6 hits in 10 CRISPR screens.
DR   PRO; PR:P53326; -.
DR   Proteomes; UP000002311; Chromosome VII.
DR   RNAct; P53326; Protein.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0005741; C:mitochondrial outer membrane; HDA:SGD.
DR   GO; GO:0005739; C:mitochondrion; HDA:SGD.
DR   GO; GO:0005886; C:plasma membrane; IDA:SGD.
DR   GO; GO:0005628; C:prospore membrane; HDA:SGD.
DR   CDD; cd07389; MPP_PhoD; 1.
DR   Gene3D; 3.60.21.70; PhoD-like phosphatase; 1.
DR   InterPro; IPR018946; PhoD-like_MPP.
DR   InterPro; IPR038607; PhoD-like_sf.
DR   InterPro; IPR043904; PhoD_2-like.
DR   PANTHER; PTHR46689; MEMBRANE PROTEIN, PUTATIVE-RELATED; 1.
DR   PANTHER; PTHR46689:SF1; PHOD-LIKE PHOSPHATASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF19050; PhoD_2; 2.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..701
FT                   /note="Uncharacterized protein YGR266W"
FT                   /id="PRO_0000202864"
SQ   SEQUENCE   701 AA;  81191 MW;  AEDA81393C8849BE CRC64;
     MHATNWFDDW NPEALYRDDV TGCDDCSETS PIPKSGIICG PILRLINMDF KEKTYEGSIM
     VVVRGEENFP KITYQLGPSL PSEDEDIEVN EAFFEGKLFH KDILKDDNIW FYRYEIKLPM
     SNYEQMVKYA VDGTMEPHYR FFVPSFTQNS NVISYSCNGF SLSVDTSKFK GSLWYDVLKK
     HRYVHYHAIL GGGDQIYSDN IKLHAPNLKA WLETKDPIKK YNTQTTEETK EQIRQFYLEH
     YLNWYGYGHW YGSTPKSKTT QKCFVKSLAC IPAINVWDDH DIIDGYGSYN DSFMKTENFL
     TVGRMAYRYY MLFQQHVSAS KQDGDEYAYL KSKQWILGNE KGSSYIGERS HSIFSWLGPK
     MAMLGLDCRT ERKLHEIFSE RSYSLIWERV EREIKNLKGG HLLLMLGIPI AYPRLVWLEW
     LFTSKLLAPI KYLSKKGIFA SGFVNEFNGD VELLDDLNDH WCARHHKKER NYLIMKLQDI
     GAKYGVRITI LSGDVHLASV GRFRAKIHRH HLIMSEEKEK ENTRIIEEPT KDVRLIFNII
     ASAIVNTPPP DAMATLLQKR CRLHHFDLET DEDAVPIFAK EVDGVHKRKE SCFMNKRNWS
     DIIPIENLLN NPQLSKELGV KVGDIVIPGI ITEQQKLQKL ENDDQINSYP VTSGGLFTTI
     HVERDANQTN SQTVSYCLPI PELTVTCERL SHKGIKHLNI T
//