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Protein

Uncharacterized RNA-binding protein YGR250C

Gene

YGR250C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • nucleotide binding Source: InterPro
  • RNA binding Source: SGD
Complete GO annotation...

Keywords - Ligandi

RNA-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-30923-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized RNA-binding protein YGR250C
Gene namesi
Ordered Locus Names:YGR250C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VII

Organism-specific databases

EuPathDBiFungiDB:YGR250C.
SGDiS000003482. YGR250C.

Subcellular locationi

GO - Cellular componenti

  • cytoplasmic stress granule Source: SGD
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000820301 – 781Uncharacterized RNA-binding protein YGR250CAdd BLAST781

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei29PhosphoserineCombined sources1
Modified residuei433PhosphoserineCombined sources1
Modified residuei435PhosphoserineCombined sources1
Modified residuei482PhosphoserineCombined sources1
Modified residuei485PhosphoserineCombined sources1
Modified residuei486PhosphothreonineCombined sources1
Modified residuei501PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP53316.
PRIDEiP53316.

PTM databases

iPTMnetiP53316.

Interactioni

Subunit structurei

Interacts with RBG1.1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
SGN1P405615EBI-23586,EBI-25362

Protein-protein interaction databases

BioGridi33501. 61 interactors.
DIPiDIP-5559N.
IntActiP53316. 13 interactors.
MINTiMINT-388955.

Structurei

3D structure databases

ProteinModelPortaliP53316.
SMRiP53316.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini195 – 273RRM 1PROSITE-ProRule annotationAdd BLAST79
Domaini295 – 418RRM 2PROSITE-ProRule annotationAdd BLAST124
Domaini540 – 638RRM 3PROSITE-ProRule annotationAdd BLAST99

Sequence similaritiesi

Contains 3 RRM (RNA recognition motif) domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

HOGENOMiHOG000142071.
InParanoidiP53316.
OMAiNYHVERK.
OrthoDBiEOG092C0RD0.

Family and domain databases

Gene3Di3.30.70.330. 4 hits.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 3 hits.
[Graphical view]
SMARTiSM00360. RRM. 3 hits.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 5 hits.
PROSITEiPS50102. RRM. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P53316-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIAEEPSDE VISSGPEDTD ICSQQTSASA EAGDQSIKIE RKTSTGLQLE
60 70 80 90 100
QLANTNLLTI RIKWQLQEEE DDHCNSRITD QIMDTIQHYK GISVNNSDTE
110 120 130 140 150
TYEFLPDTRR LQVLEQNKDI YLYEHGSQEY EKSYKDNEEE DDWRYDTVLQ
160 170 180 190 200
AQFKYPKSLE NACTDISELL KSEPIGQHID KWSIGVNKHA LTYPGNIFVG
210 220 230 240 250
GIAKSLSIGE LSFLFSKYGP ILSMKLIYDK TKGEPNGYGF ISYPLGSQAS
260 270 280 290 300
LCIKELNGRT VNGSTLFINY HVERKERERI HWDHVKENNN DDNFRCLFIG
310 320 330 340 350
NLPYHNPEKV ETLITPKEVI EVIKKELSKK FPDFDIISYY FPKRSNTRSS
360 370 380 390 400
SSVSFNEEGS VESNKSSNNT NGNAQDEDML KGYGFIKLIN HEQALAAIET
410 420 430 440 450
FNGFMWHGNR LVVNKAVQHK VYNNHNSHDR HPSISNHNDM EVLEFANNPM
460 470 480 490 500
YDYNNYTYDR YYFNNNKNGN SNDTSNVRYF DSVRSTPVAE KMDLFYPQRE
510 520 530 540 550
SFSEGRGQRV PRFMGNKFDM YQYPSTSYSL PIPMSNQQES NLYVKHIPLS
560 570 580 590 600
WTDEDLYDFY KSFGEIISVK VITVGGSKNK YRQQSNDSSS DNDLPVGSSR
610 620 630 640 650
GYGFVSFESP LDAAKAILNT DGYQVSKDQV LSVSFAQKRG NLSSSDDDDQ
660 670 680 690 700
SQTDNSSKFQ NFQPHNDYHK AYPTKYNKKF INALMTQNQS QQQVSRENYF
710 720 730 740 750
IPLQYPNTNT KPVNSYNLIS ANQNNANWMM PMFPSFGFIP QVPPVPYIIP
760 770 780
PQNPAANHIP IMANGSNEEE EFSSGDYSMD Y
Length:781
Mass (Da):89,513
Last modified:October 1, 1996 - v1
Checksum:iC2CA1CBF5F6D395B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z73035 Genomic DNA. Translation: CAA97279.1.
BK006941 Genomic DNA. Translation: DAA08341.1.
PIRiS64576.
RefSeqiNP_011766.3. NM_001181379.3.

Genome annotation databases

EnsemblFungiiYGR250C; YGR250C; YGR250C.
GeneIDi853165.
KEGGisce:YGR250C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z73035 Genomic DNA. Translation: CAA97279.1.
BK006941 Genomic DNA. Translation: DAA08341.1.
PIRiS64576.
RefSeqiNP_011766.3. NM_001181379.3.

3D structure databases

ProteinModelPortaliP53316.
SMRiP53316.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi33501. 61 interactors.
DIPiDIP-5559N.
IntActiP53316. 13 interactors.
MINTiMINT-388955.

PTM databases

iPTMnetiP53316.

Proteomic databases

MaxQBiP53316.
PRIDEiP53316.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYGR250C; YGR250C; YGR250C.
GeneIDi853165.
KEGGisce:YGR250C.

Organism-specific databases

EuPathDBiFungiDB:YGR250C.
SGDiS000003482. YGR250C.

Phylogenomic databases

HOGENOMiHOG000142071.
InParanoidiP53316.
OMAiNYHVERK.
OrthoDBiEOG092C0RD0.

Enzyme and pathway databases

BioCyciYEAST:G3O-30923-MONOMER.

Miscellaneous databases

PROiP53316.

Family and domain databases

Gene3Di3.30.70.330. 4 hits.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 3 hits.
[Graphical view]
SMARTiSM00360. RRM. 3 hits.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 5 hits.
PROSITEiPS50102. RRM. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYG5B_YEAST
AccessioniPrimary (citable) accession number: P53316
Secondary accession number(s): D6VV30
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: November 2, 2016
This is version 138 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 1910 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.