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P53315

- SOL4_YEAST

UniProt

P53315 - SOL4_YEAST

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Protein

6-phosphogluconolactonase 4

Gene

SOL4

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.1 Publication

Catalytic activityi

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.

Pathwayi

GO - Molecular functioni

  1. 6-phosphogluconolactonase activity Source: SGD

GO - Biological processi

  1. pentose-phosphate shunt, oxidative branch Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciYEAST:MONOMER3O-4047.
UniPathwayiUPA00115; UER00409.

Names & Taxonomyi

Protein namesi
Recommended name:
6-phosphogluconolactonase 4 (EC:3.1.1.31)
Short name:
6PGL
Gene namesi
Name:SOL4
Ordered Locus Names:YGR248W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome VII

Organism-specific databases

CYGDiYGR248w.
SGDiS000003480. SOL4.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: SGD
  2. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2552556-phosphogluconolactonase 4PRO_0000090085Add
BLAST

Proteomic databases

MaxQBiP53315.
PaxDbiP53315.
PeptideAtlasiP53315.

Expressioni

Gene expression databases

GenevestigatoriP53315.

Interactioni

Protein-protein interaction databases

BioGridi33499. 41 interactions.
IntActiP53315. 4 interactions.
MINTiMINT-2780364.
STRINGi4932.YGR248W.

Structurei

3D structure databases

ProteinModelPortaliP53315.
SMRiP53315. Positions 39-252.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0363.
GeneTreeiENSGT00550000075110.
HOGENOMiHOG000256285.
InParanoidiP53315.
KOiK01057.
OMAiNEYADIT.
OrthoDBiEOG7MD51D.

Family and domain databases

InterProiIPR005900. 6-phosphogluconolactonase_DevB.
IPR006148. Glc/Gal-6P_isomerase.
[Graphical view]
PfamiPF01182. Glucosamine_iso. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01198. pgl. 1 hit.

Sequencei

Sequence statusi: Complete.

P53315-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVKLQRFSEK KSLIHEFGKF ILEKQESALT GDADAVFNIA ISGGSMNQAL
60 70 80 90 100
YESLVNDKNI FPHIKWPQWR IFFCDERLVP FEDPQSNYGQ FKKTVLDPLV
110 120 130 140 150
HQGNQLNLGP TVYTINESLI GGGETANRKI AEEYASMLPA SFDLILLGCG
160 170 180 190 200
EDGHTCSLFP GVEFNYLVEE MDRKVLWCNN SPKAPKDRIT FTLAVVAEAK
210 220 230 240 250
SVCFLVRGAA KKAIMHDVLI VKNSELPSVL VNEMVGTKVT WFLDDEAGAL

IPENC
Length:255
Mass (Da):28,448
Last modified:October 1, 1996 - v1
Checksum:i691C9DDA04E5BEF6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z73033 Genomic DNA. Translation: CAA97277.1.
BK006941 Genomic DNA. Translation: DAA08339.1.
PIRiS64574.
RefSeqiNP_011764.3. NM_001181377.3.

Genome annotation databases

EnsemblFungiiYGR248W; YGR248W; YGR248W.
GeneIDi853163.
KEGGisce:YGR248W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z73033 Genomic DNA. Translation: CAA97277.1 .
BK006941 Genomic DNA. Translation: DAA08339.1 .
PIRi S64574.
RefSeqi NP_011764.3. NM_001181377.3.

3D structure databases

ProteinModelPortali P53315.
SMRi P53315. Positions 39-252.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 33499. 41 interactions.
IntActi P53315. 4 interactions.
MINTi MINT-2780364.
STRINGi 4932.YGR248W.

Proteomic databases

MaxQBi P53315.
PaxDbi P53315.
PeptideAtlasi P53315.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YGR248W ; YGR248W ; YGR248W .
GeneIDi 853163.
KEGGi sce:YGR248W.

Organism-specific databases

CYGDi YGR248w.
SGDi S000003480. SOL4.

Phylogenomic databases

eggNOGi COG0363.
GeneTreei ENSGT00550000075110.
HOGENOMi HOG000256285.
InParanoidi P53315.
KOi K01057.
OMAi NEYADIT.
OrthoDBi EOG7MD51D.

Enzyme and pathway databases

UniPathwayi UPA00115 ; UER00409 .
BioCyci YEAST:MONOMER3O-4047.

Miscellaneous databases

NextBioi 973270.

Gene expression databases

Genevestigatori P53315.

Family and domain databases

InterProi IPR005900. 6-phosphogluconolactonase_DevB.
IPR006148. Glc/Gal-6P_isomerase.
[Graphical view ]
Pfami PF01182. Glucosamine_iso. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR01198. pgl. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Analysis of a 17.9 kb region from Saccharomyces cerevisiae chromosome VII reveals the presence of eight open reading frames, including BRF1 (TFIIIB70) and GCN5 genes."
    Feroli F., Carignani G., Pavanello A., Guerreiro P., Azevedo D., Rodrigues-Pousada C., Melchioretto P., Panzeri L., Agostoni Carbone M.L.
    Yeast 13:373-377(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 96604 / S288c / FY1679.
  2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
    Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E.
    , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
    Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  5. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  6. "Division of labor among the yeast Sol proteins implicated in tRNA nuclear export and carbohydrate metabolism."
    Stanford D.R., Whitney M.L., Hurto R.L., Eisaman D.M., Shen W.-C., Hopper A.K.
    Genetics 168:117-127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION.

Entry informationi

Entry nameiSOL4_YEAST
AccessioniPrimary (citable) accession number: P53315
Secondary accession number(s): D6VV28
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: October 29, 2014
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 4320 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

External Data

Dasty 3