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Protein

Mitochondrial 37S ribosomal protein S27

Gene

RSM27

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.2 Publications

GO - Molecular functioni

  • structural constituent of ribosome Source: SGD

GO - Biological processi

  • mitochondrial translation Source: SGD

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-30897-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial 37S ribosomal protein S27
Alternative name(s):
Mitochondrial small ribosomal subunit protein mS331 Publication
Gene namesi
Name:RSM27
Ordered Locus Names:YGR215W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VII

Organism-specific databases

EuPathDBiFungiDB:YGR215W
SGDiS000003447 RSM27

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002028471 – 110Mitochondrial 37S ribosomal protein S27Add BLAST110

Proteomic databases

MaxQBiP53305
PaxDbiP53305
PRIDEiP53305

Interactioni

Subunit structurei

Component of the mitochondrial small ribosomal subunit (mt-SSU). Mature yeast 74S mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S small subunit contains a 15S ribosomal RNA (15S mt-rRNA) and 34 different proteins. The 54S large subunit contains a 21S rRNA (21S mt-rRNA) and 46 different proteins.3 Publications

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi33468, 98 interactors
DIPiDIP-5606N
IntActiP53305, 10 interactors
MINTiP53305
STRINGi4932.YGR215W

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5MRCelectron microscopy3.25XX1-96[»]
5MREelectron microscopy3.75XX1-96[»]
5MRFelectron microscopy4.97XX1-96[»]
ProteinModelPortaliP53305
SMRiP53305
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi103 – 110Poly-Lys8

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000159261
InParanoidiP53305
OMAiIFNTTFN
OrthoDBiEOG092C5NWH

Family and domain databases

InterProiView protein in InterPro
IPR013219 Ribosomal_S27/S33_mit
PANTHERiPTHR13362 PTHR13362, 2 hits
PfamiView protein in Pfam
PF08293 MRP-S33, 1 hit

Sequencei

Sequence statusi: Complete.

P53305-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNVPKARLLK VAELSAKIFD QNFNPSGIRT GSKILNERLK GPSVASYYGN
60 70 80 90 100
PDILKFRHLK TLYPDIEFVD LEEQYRLSMV EAKKRRGKGA PKKMKKDAAA
110
TAKGKGKKKK
Length:110
Mass (Da):12,393
Last modified:October 1, 1996 - v1
Checksum:i05008CA4F5D09004
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z73000 Genomic DNA Translation: CAA97242.1
AY558379 Genomic DNA Translation: AAS56705.1
BK006941 Genomic DNA Translation: DAA08309.1
PIRiS64538
RefSeqiNP_011731.3, NM_001181344.3

Genome annotation databases

EnsemblFungiiYGR215W; YGR215W; YGR215W
GeneIDi853129
KEGGisce:YGR215W

Similar proteinsi

Entry informationi

Entry nameiRT27_YEAST
AccessioniPrimary (citable) accession number: P53305
Secondary accession number(s): D6VUZ8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: March 28, 2018
This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
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Main funding by: National Institutes of Health