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P53303 (ZPR1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 126. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Zinc finger protein ZPR1
Gene names
Name:ZPR1
Ordered Locus Names:YGR211W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length486 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Binds to the elongation factor 1-alpha.

Subcellular location

Cytoplasm. Nucleus. Note: Translocates to the nucleus after nutrient stimulation.

Miscellaneous

Present with 39900 molecules/cell in log phase SD medium.

Sequence similarities

Belongs to the ZPR1 family.

Sequence caution

The sequence AAA85586.1 differs from that shown. Reason: Frameshift at positions 171 and 419.

The sequence AAA85587.1 differs from that shown. Reason: Frameshift at positions 171 and 419.

Binary interactions

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 486486Zinc finger protein ZPR1
PRO_0000119040

Regions

Zinc finger54 – 8633C4-type 1
Zinc finger295 – 32733C4-type 2

Amino acid modifications

Modified residue231Phosphoserine Ref.8
Modified residue4071Phosphothreonine Ref.7

Sequences

Sequence LengthMass (Da)Tools
P53303 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: F523AF8AB5B8ACA0

FASTA48655,072
        10         20         30         40         50         60 
MSEQKEDLFK PVGEAAAEVE DESIAEQNKA NDGVKLTGAQ DAMGHPVQEI ESLCMNCGKN 

        70         80         90        100        110        120 
GTTRLLLTSI PYFREIIIMS FDCPHCGFKN CEIQPASQIQ EKGSRYVLKV ECREDFNRQV 

       130        140        150        160        170        180 
IKSETATCKF VELDIEIPAK RGQLTTVEGL LSEMIDDLSQ DQEMRKSIDE ALYKKIDDFI 

       190        200        210        220        230        240 
QKVKSYINCE PNTIPITFIL DDPAGNSWIE YKPGEPQHKW SHTQYVRTDE QNVQVGIITR 

       250        260        270        280        290        300 
DQLEQRRQEQ LKQLANRERN PSESVKVGSA NPQFLSDATD IENFNNEVQT FRASCPSCTQ 

       310        320        330        340        350        360 
ECETHMKPVN IPHFKEVIIM STVCDHCGYK SNEVKTGGAI PDKGRRITLY CDDAADLSRD 

       370        380        390        400        410        420 
ILKSETCSMV IPELHLDIQE GTLGGRFTTL EGLLRQVYEE LESRIFTQTS DSMDEATKAR 

       430        440        450        460        470        480 
WVEFFAKLKE AIAGKVKFTV IMEDPLAGSY IQNVYAPDPD PNMTIEDYER TKEQNEDLGL 


SDIKVE 

« Hide

References

« Hide 'large scale' references
[1]"Interaction of ZPR1 with translation elongation factor-1alpha in proliferating cells."
Gangwani L., Mikrut M., Galcheva-Gargova Z., Davis R.J.
J. Cell Biol. 143:1471-1484(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Sequence analysis of 203 kilobases from Saccharomyces cerevisiae chromosome VII."
Rieger M., Brueckner M., Schaefer M., Mueller-Auer S.
Yeast 13:1077-1090(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]"The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E. expand/collapse author list , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[4]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[5]"Analysis of the 15.6-kb fragment encompassing the ADE3 gene."
Song J.M., Cheung E., Rabinowitz J.C.
Submitted (NOV-1995) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-459.
Strain: S288c / GRF88.
[6]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[7]"A multidimensional chromatography technology for in-depth phosphoproteome analysis."
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-407, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[8]"Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-23, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF019769 Genomic DNA. Translation: AAC33516.1.
Z72996 Genomic DNA. Translation: CAA97238.1.
U40843 Genomic DNA. Translation: AAA85586.1. Frameshift.
U40843 Genomic DNA. Translation: AAA85587.1. Frameshift.
BK006941 Genomic DNA. Translation: DAA08305.1.
PIRS64534.
RefSeqNP_011727.3. NM_001181340.3.

3D structure databases

ProteinModelPortalP53303.
SMRP53303. Positions 50-477.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33464. 20 interactions.
DIPDIP-4419N.
IntActP53303. 7 interactions.
MINTMINT-490492.

Proteomic databases

PaxDbP53303.
PeptideAtlasP53303.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYGR211W; YGR211W; YGR211W.
GeneID853125.
KEGGsce:YGR211W.

Organism-specific databases

CYGDYGR211w.
SGDS000003443. ZPR1.

Phylogenomic databases

eggNOGCOG1779.
GeneTreeENSGT00390000005306.
HOGENOMHOG000216492.
KOK06874.
OMATVCDHCG.
OrthoDBEOG7WMCW5.

Enzyme and pathway databases

BioCycYEAST:G3O-30893-MONOMER.

Gene expression databases

GenevestigatorP53303.

Family and domain databases

InterProIPR004457. Znf_ZPR1.
[Graphical view]
PfamPF03367. zf-ZPR1. 2 hits.
[Graphical view]
SMARTSM00709. Zpr1. 2 hits.
[Graphical view]
TIGRFAMsTIGR00310. ZPR1_znf. 2 hits.
ProtoNetSearch...

Other

NextBio973169.
PROP53303.

Entry information

Entry nameZPR1_YEAST
AccessionPrimary (citable) accession number: P53303
Secondary accession number(s): D6VUZ4, Q02807, Q02808
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: March 19, 2014
This is version 126 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome VII

Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families