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Protein

Ribosome-interacting GTPase 2

Gene

RBG2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in ribosomal function.1 Publication

Miscellaneous

Present with 6200 molecules/cell in log phase SD medium.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi70 – 77GTPPROSITE-ProRule annotation8
Nucleotide bindingi116 – 120GTPPROSITE-ProRule annotation5
Nucleotide bindingi250 – 253GTPPROSITE-ProRule annotation4

GO - Molecular functioni

  • GTP binding Source: SGD

GO - Biological processi

  • cytoplasmic translation Source: SGD
  • positive regulation of cellular response to amino acid starvation Source: SGD

Keywordsi

LigandGTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-30869-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosome-interacting GTPase 2
Alternative name(s):
GTP-binding protein RBG2
Gene namesi
Name:RBG2
Synonyms:GIR1
Ordered Locus Names:YGR173W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VII

Organism-specific databases

EuPathDBiFungiDB:YGR173W
SGDiS000003405 RBG2

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002054501 – 368Ribosome-interacting GTPase 2Add BLAST368

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei364PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP53295
PaxDbiP53295
PRIDEiP53295

PTM databases

iPTMnetiP53295

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
GIR2Q037685EBI-23421,EBI-7618

Protein-protein interaction databases

BioGridi33425, 75 interactors
DIPiDIP-2827N
IntActiP53295, 25 interactors
MINTiP53295
STRINGi4932.YGR173W

Structurei

3D structure databases

ProteinModelPortaliP53295
SMRiP53295
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini64 – 292OBG-type GPROSITE-ProRule annotationAdd BLAST229

Sequence similaritiesi

Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.PROSITE-ProRule annotation

Phylogenomic databases

GeneTreeiENSGT00550000075059
InParanoidiP53295
KOiK06944
OMAiMIREDIT
OrthoDBiEOG092C332H

Family and domain databases

Gene3Di3.10.20.30, 1 hit
InterProiView protein in InterPro
IPR012675 Beta-grasp_dom_sf
IPR031167 G_OBG
IPR031662 GTP-binding_2
IPR006074 GTP1-OBG_CS
IPR006073 GTP_binding_domain
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR004095 TGS
IPR012676 TGS-like
PfamiView protein in Pfam
PF01926 MMR_HSR1, 1 hit
PF16897 MMR_HSR1_Xtn, 1 hit
PF02824 TGS, 1 hit
PRINTSiPR00326 GTP1OBG
SUPFAMiSSF52540 SSF52540, 1 hit
SSF81271 SSF81271, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51710 G_OBG, 1 hit
PS00905 GTP1_OBG, 1 hit

Sequencei

Sequence statusi: Complete.

P53295-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGIIDKIKAI EEEMARTQKN KATEHHLGLL KGKLARYRQQ LLADEAGSGG
60 70 80 90 100
GGGSGFEVAK SGDARVVLIG YPSVGKSSLL GKITTTKSEI AHYAFTTLTS
110 120 130 140 150
VPGVLKYQGA EIQIVDLPGI IYGASQGKGR GRQVVATART ADLVLMVLDA
160 170 180 190 200
TKSEHQRASL EKELENVGIR LNKEKPNIYY KKKETGGVKV TFTSPPKTNL
210 220 230 240 250
TEQAIKMILR DYRIHNAEVL VRDDQCTIDD FIDVINEQHR NYVKCLYVYN
260 270 280 290 300
KIDAVSLEEV DKLAREPNTV VMSCEMDLGL QDVVEEIWYQ LNLSRVYTKK
310 320 330 340 350
RGVRPVFDDP LVVRNNSTIG DLCHGIHRDF KDKFKYALVW GSSAKHSPQK
360
CGLNHRIDDE DVVSLFAK
Length:368
Mass (Da):41,006
Last modified:October 1, 1996 - v1
Checksum:iD144569C9C5D777C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z72958 Genomic DNA Translation: CAA97199.1
BK006941 Genomic DNA Translation: DAA08268.1
PIRiS64487
RefSeqiNP_011689.1, NM_001181302.1

Genome annotation databases

EnsemblFungiiYGR173W; YGR173W; YGR173W
GeneIDi853083
KEGGisce:YGR173W

Similar proteinsi

Entry informationi

Entry nameiRBG2_YEAST
AccessioniPrimary (citable) accession number: P53295
Secondary accession number(s): D6VUV7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: May 23, 2018
This is version 142 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

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