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Protein

Late endosome and vacuole interface protein 11

Gene

ENV11

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Involved in vacuolar processing and morphology.2 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri84 – 138BED-typePROSITE-ProRule annotationAdd BLAST55

GO - Molecular functioni

GO - Biological processi

  • vacuolar protein processing Source: SGD
  • vacuole organization Source: SGD
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciYEAST:G3O-30784-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Late endosome and vacuole interface protein 11
Gene namesi
Name:ENV11
Ordered Locus Names:YGR071C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VII

Organism-specific databases

EuPathDBiFungiDB:YGR071C.
SGDiS000003303. ENV11.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Disruption phenotypei

Exhibits cold sensitivity, a significant increase in cells with fragmented vacuoles, internal accumulation of precursor CPY, increased glycogen accumulation, and displays elongated buds.2 Publications

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002028061 – 860Late endosome and vacuole interface protein 11Add BLAST860

Proteomic databases

MaxQBiP53246.
PRIDEiP53246.

Interactioni

Protein-protein interaction databases

BioGridi33314. 51 interactors.
DIPiDIP-5521N.
IntActiP53246. 7 interactors.
MINTiMINT-490055.

Structurei

3D structure databases

ProteinModelPortaliP53246.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the VID22 family.Curated
Contains 1 BED-type zinc finger.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri84 – 138BED-typePROSITE-ProRule annotationAdd BLAST55

Keywords - Domaini

Zinc-finger

Phylogenomic databases

GeneTreeiENSGT00530000068309.
InParanoidiP53246.
OrthoDBiEOG092C27YN.

Family and domain databases

InterProiIPR003656. Znf_BED.
[Graphical view]
PfamiPF02892. zf-BED. 1 hit.
[Graphical view]
SMARTiSM00614. ZnF_BED. 1 hit.
[Graphical view]
PROSITEiPS50808. ZF_BED. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P53246-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNTALDDLHG DLVTLEDNEI INNSDHSSSH STSHEEEDEE EDDTEDIELI
60 70 80 90 100
EKDGNKILSS RIHPEDEIIN DGLNIWIPVQ MLKKNIAKFW SHFLAIEKKL
110 120 130 140 150
TKVKCKHCGE ILTRSDASLT KTFRSHLKTK HNISANKNFY SMNFTVGDSN
160 170 180 190 200
LKNNTSSTEI TRRHGYDSLT FNSDQSFKCF DIGKLQSSNY LSISQLVAIV
210 220 230 240 250
IASENLPLNF FENVSFKSLL SKFHRIPPLT TNIIEESIIG LSKSIDELIR
260 270 280 290 300
RSISRNDTQL PFTIHLSDSK ESNQPLYLKY SREIRAQLSN LDLSHLISVN
310 320 330 340 350
FTELAGKRSL FSLQLFDNTN KVSKGLPLSI FVRKTTDIDI SVWQEQLNNL
360 370 380 390 400
YSKYPGLQKS VISITLPQSH YTMVLENRNS HNFTFHSGSV REIKYHTCIV
410 420 430 440 450
SELLHCFLQP LFNVPTESML SSFSVAKENH SGGSLLDSLI DFSHIDLSST
460 470 480 490 500
ILGKICCLIE EVNLNDSLKS DFLLYCQNYT QPNCNELTSI LSCNCDRFSA
510 520 530 540 550
LKSILEKFAN LVPFFKSINS HLENESLSES DFRLINTVEE TLRTFEQSIE
560 570 580 590 600
YFASSAPLKF THTLVFIIKF ELYLTEIIRS FKFTKSKKPF EKILARLLKV
610 620 630 640 650
KDLYLLDDVN LIGAFLYPSI FQSKSLLNEI FGTTSVNKIV HNMTKIVLRY
660 670 680 690 700
LKNFINITNF RSSNSGGESG RNSGNNLLSD YEAIFMKESR DVELLCNTKL
710 720 730 740 750
TAPLTEDSLL VQIIRDDLLR YVNRIAHELP NAYHDYLNDN DISFDGSHFT
760 770 780 790 800
KHELSEENDS NSGEWCLNPM EETFDIHIPI SDSIWNNYIS SKNKIEVIDI
810 820 830 840 850
LLQLLSVNST SSIRSELSSL TANQDFSTKL SEETIKIKLL NSQFNLEKIN
860
FHSGSIFDAC
Length:860
Mass (Da):98,109
Last modified:October 1, 1996 - v1
Checksum:i308D65E456C8FF3B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z72856 Genomic DNA. Translation: CAA97073.1.
BK006941 Genomic DNA. Translation: DAA08165.1.
PIRiS64366.
RefSeqiNP_011585.3. NM_001181200.3.

Genome annotation databases

EnsemblFungiiYGR071C; YGR071C; YGR071C.
GeneIDi852962.
KEGGisce:YGR071C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z72856 Genomic DNA. Translation: CAA97073.1.
BK006941 Genomic DNA. Translation: DAA08165.1.
PIRiS64366.
RefSeqiNP_011585.3. NM_001181200.3.

3D structure databases

ProteinModelPortaliP53246.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi33314. 51 interactors.
DIPiDIP-5521N.
IntActiP53246. 7 interactors.
MINTiMINT-490055.

Proteomic databases

MaxQBiP53246.
PRIDEiP53246.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYGR071C; YGR071C; YGR071C.
GeneIDi852962.
KEGGisce:YGR071C.

Organism-specific databases

EuPathDBiFungiDB:YGR071C.
SGDiS000003303. ENV11.

Phylogenomic databases

GeneTreeiENSGT00530000068309.
InParanoidiP53246.
OrthoDBiEOG092C27YN.

Enzyme and pathway databases

BioCyciYEAST:G3O-30784-MONOMER.

Miscellaneous databases

PROiP53246.

Family and domain databases

InterProiIPR003656. Znf_BED.
[Graphical view]
PfamiPF02892. zf-BED. 1 hit.
[Graphical view]
SMARTiSM00614. ZnF_BED. 1 hit.
[Graphical view]
PROSITEiPS50808. ZF_BED. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiENV11_YEAST
AccessioniPrimary (citable) accession number: P53246
Secondary accession number(s): D6VUK4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: November 2, 2016
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 1050 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.