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P53237

- LST7_YEAST

UniProt

P53237 - LST7_YEAST

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Protein

Protein LST7

Gene

LST7

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Required for the nitrogen-regulated transport of amino acid permeases GAP1 and PUT4 from the Golgi to the cell surface.1 Publication

GO - Molecular functioni

  1. protein transporter activity Source: SGD

GO - Biological processi

  1. Golgi to plasma membrane transport Source: SGD
  2. intracellular protein transport Source: SGD
  3. protein transport Source: SGD
  4. vesicle-mediated transport Source: SGD
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-30774-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein LST7
Alternative name(s):
Lethal with SEC thirteen protein 7
Gene namesi
Name:LST7
Ordered Locus Names:YGR057C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome VII

Organism-specific databases

CYGDiYGR057c.
SGDiS000003289. LST7.

Subcellular locationi

GO - Cellular componenti

  1. vesicle coat Source: SGD
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 242242Protein LST7PRO_0000202801Add
BLAST

Proteomic databases

MaxQBiP53237.
PaxDbiP53237.

Expressioni

Gene expression databases

GenevestigatoriP53237.

Interactioni

Protein-protein interaction databases

BioGridi33302. 14 interactions.
DIPiDIP-1424N.
IntActiP53237. 2 interactions.
MINTiMINT-395024.
STRINGi4932.YGR057C.

Structurei

3D structure databases

ProteinModelPortaliP53237.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiNOG324021.
HOGENOMiHOG000000953.
InParanoidiP53237.
OMAiYSSIRYQ.
OrthoDBiEOG7PP5JM.

Family and domain databases

InterProiIPR021713. Folliculin.
[Graphical view]
PANTHERiPTHR31441. PTHR31441. 1 hit.

Sequencei

Sequence statusi: Complete.

P53237-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSSTVISLAH FCDKHGPRII SVTQSAEKGT LGEELLVPDY PTESYCESCL
60 70 80 90 100
LQFPEESTRS MRCFIEDVPF ITTQYSSIRY QLLNSIIKRA FSEETMIYDN
110 120 130 140 150
MPFIFFDDLR GLNLVIGFKL YDENARGNER RYCFILTVDS RSHDDSMKML
160 170 180 190 200
SEHWNFIIGG FDKMIAYIKN IHKSEFLGKN KTVENNLETL NNNAFIGSYL
210 220 230 240
RANKSKFGRN LVSLTDDKFL FVRIHKWNSF LLHTVMNENK LP
Length:242
Mass (Da):28,136
Last modified:May 16, 2006 - v2
Checksum:i410B0A6E670FACA2
GO

Sequence cautioni

The sequence CAA97058.1 differs from that shown. Reason: Erroneous initiation. Curated
The sequence CAA97060.1 differs from that shown. Reason: Erroneous initiation. Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti4 – 41T → I in strain: SK1.

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ115391 Genomic DNA. Translation: AAZ22470.1.
Z72842 Genomic DNA. Translation: CAA97058.1. Different initiation.
Z72843 Genomic DNA. Translation: CAA97060.1. Different initiation.
BK006941 Genomic DNA. Translation: DAA08153.1.
PIRiS64351.
RefSeqiNP_011571.4. NM_001181186.3.

Genome annotation databases

EnsemblFungiiYGR057C; YGR057C; YGR057C.
GeneIDi852948.
KEGGisce:YGR057C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ115391 Genomic DNA. Translation: AAZ22470.1 .
Z72842 Genomic DNA. Translation: CAA97058.1 . Different initiation.
Z72843 Genomic DNA. Translation: CAA97060.1 . Different initiation.
BK006941 Genomic DNA. Translation: DAA08153.1 .
PIRi S64351.
RefSeqi NP_011571.4. NM_001181186.3.

3D structure databases

ProteinModelPortali P53237.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 33302. 14 interactions.
DIPi DIP-1424N.
IntActi P53237. 2 interactions.
MINTi MINT-395024.
STRINGi 4932.YGR057C.

Proteomic databases

MaxQBi P53237.
PaxDbi P53237.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YGR057C ; YGR057C ; YGR057C .
GeneIDi 852948.
KEGGi sce:YGR057C.

Organism-specific databases

CYGDi YGR057c.
SGDi S000003289. LST7.

Phylogenomic databases

eggNOGi NOG324021.
HOGENOMi HOG000000953.
InParanoidi P53237.
OMAi YSSIRYQ.
OrthoDBi EOG7PP5JM.

Enzyme and pathway databases

BioCyci YEAST:G3O-30774-MONOMER.

Miscellaneous databases

NextBioi 972699.

Gene expression databases

Genevestigatori P53237.

Family and domain databases

InterProi IPR021713. Folliculin.
[Graphical view ]
PANTHERi PTHR31441. PTHR31441. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Quantitative trait loci mapped to single-nucleotide resolution in yeast."
    Deutschbauer A.M., Davis R.W.
    Nat. Genet. 37:1333-1340(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: SK1.
  2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
    Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E.
    , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
    Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. "Control of amino acid permease sorting in the late secretory pathway of Saccharomyces cerevisiae by SEC13, LST4, LST7 and LST8."
    Roberg K.J., Bickel S., Rowley N., Kaiser C.A.
    Genetics 147:1569-1584(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  5. "Sequencing and comparison of yeast species to identify genes and regulatory elements."
    Kellis M., Patterson N., Endrizzi M., Birren B.W., Lander E.S.
    Nature 423:241-254(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION OF PROBABLE INITIATION SITE.
  6. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiLST7_YEAST
AccessioniPrimary (citable) accession number: P53237
Secondary accession number(s): D6VUJ2, Q45U29
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: May 16, 2006
Last modified: October 29, 2014
This is version 93 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 656 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

External Data

Dasty 3