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P53237

- LST7_YEAST

UniProt

P53237 - LST7_YEAST

Protein

Protein LST7

Gene

LST7

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 92 (01 Oct 2014)
      Sequence version 2 (16 May 2006)
      Previous versions | rss
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    Functioni

    Required for the nitrogen-regulated transport of amino acid permeases GAP1 and PUT4 from the Golgi to the cell surface.1 Publication

    GO - Molecular functioni

    1. protein transporter activity Source: SGD

    GO - Biological processi

    1. Golgi to plasma membrane transport Source: SGD
    2. intracellular protein transport Source: SGD
    3. protein transport Source: SGD
    4. vesicle-mediated transport Source: SGD

    Enzyme and pathway databases

    BioCyciYEAST:G3O-30774-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein LST7
    Alternative name(s):
    Lethal with SEC thirteen protein 7
    Gene namesi
    Name:LST7
    Ordered Locus Names:YGR057C
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome VII

    Organism-specific databases

    CYGDiYGR057c.
    SGDiS000003289. LST7.

    Subcellular locationi

    GO - Cellular componenti

    1. vesicle coat Source: SGD

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 242242Protein LST7PRO_0000202801Add
    BLAST

    Proteomic databases

    MaxQBiP53237.
    PaxDbiP53237.

    Expressioni

    Gene expression databases

    GenevestigatoriP53237.

    Interactioni

    Protein-protein interaction databases

    BioGridi33302. 14 interactions.
    DIPiDIP-1424N.
    IntActiP53237. 2 interactions.
    MINTiMINT-395024.
    STRINGi4932.YGR057C.

    Structurei

    3D structure databases

    ProteinModelPortaliP53237.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG324021.
    HOGENOMiHOG000000953.
    OMAiYSSIRYQ.
    OrthoDBiEOG7PP5JM.

    Family and domain databases

    InterProiIPR021713. Folliculin.
    [Graphical view]
    PANTHERiPTHR31441. PTHR31441. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P53237-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSSTVISLAH FCDKHGPRII SVTQSAEKGT LGEELLVPDY PTESYCESCL    50
    LQFPEESTRS MRCFIEDVPF ITTQYSSIRY QLLNSIIKRA FSEETMIYDN 100
    MPFIFFDDLR GLNLVIGFKL YDENARGNER RYCFILTVDS RSHDDSMKML 150
    SEHWNFIIGG FDKMIAYIKN IHKSEFLGKN KTVENNLETL NNNAFIGSYL 200
    RANKSKFGRN LVSLTDDKFL FVRIHKWNSF LLHTVMNENK LP 242
    Length:242
    Mass (Da):28,136
    Last modified:May 16, 2006 - v2
    Checksum:i410B0A6E670FACA2
    GO

    Sequence cautioni

    The sequence CAA97058.1 differs from that shown. Reason: Erroneous initiation.
    The sequence CAA97060.1 differs from that shown. Reason: Erroneous initiation.

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti4 – 41T → I in strain: SK1.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ115391 Genomic DNA. Translation: AAZ22470.1.
    Z72842 Genomic DNA. Translation: CAA97058.1. Different initiation.
    Z72843 Genomic DNA. Translation: CAA97060.1. Different initiation.
    BK006941 Genomic DNA. Translation: DAA08153.1.
    PIRiS64351.
    RefSeqiNP_011571.4. NM_001181186.3.

    Genome annotation databases

    EnsemblFungiiYGR057C; YGR057C; YGR057C.
    GeneIDi852948.
    KEGGisce:YGR057C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ115391 Genomic DNA. Translation: AAZ22470.1 .
    Z72842 Genomic DNA. Translation: CAA97058.1 . Different initiation.
    Z72843 Genomic DNA. Translation: CAA97060.1 . Different initiation.
    BK006941 Genomic DNA. Translation: DAA08153.1 .
    PIRi S64351.
    RefSeqi NP_011571.4. NM_001181186.3.

    3D structure databases

    ProteinModelPortali P53237.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 33302. 14 interactions.
    DIPi DIP-1424N.
    IntActi P53237. 2 interactions.
    MINTi MINT-395024.
    STRINGi 4932.YGR057C.

    Proteomic databases

    MaxQBi P53237.
    PaxDbi P53237.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YGR057C ; YGR057C ; YGR057C .
    GeneIDi 852948.
    KEGGi sce:YGR057C.

    Organism-specific databases

    CYGDi YGR057c.
    SGDi S000003289. LST7.

    Phylogenomic databases

    eggNOGi NOG324021.
    HOGENOMi HOG000000953.
    OMAi YSSIRYQ.
    OrthoDBi EOG7PP5JM.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-30774-MONOMER.

    Miscellaneous databases

    NextBioi 972699.

    Gene expression databases

    Genevestigatori P53237.

    Family and domain databases

    InterProi IPR021713. Folliculin.
    [Graphical view ]
    PANTHERi PTHR31441. PTHR31441. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Quantitative trait loci mapped to single-nucleotide resolution in yeast."
      Deutschbauer A.M., Davis R.W.
      Nat. Genet. 37:1333-1340(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: SK1.
    2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
      Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E.
      , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
      Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    3. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    4. "Control of amino acid permease sorting in the late secretory pathway of Saccharomyces cerevisiae by SEC13, LST4, LST7 and LST8."
      Roberg K.J., Bickel S., Rowley N., Kaiser C.A.
      Genetics 147:1569-1584(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    5. "Sequencing and comparison of yeast species to identify genes and regulatory elements."
      Kellis M., Patterson N., Endrizzi M., Birren B.W., Lander E.S.
      Nature 423:241-254(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION OF PROBABLE INITIATION SITE.
    6. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiLST7_YEAST
    AccessioniPrimary (citable) accession number: P53237
    Secondary accession number(s): D6VUJ2, Q45U29
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1996
    Last sequence update: May 16, 2006
    Last modified: October 1, 2014
    This is version 92 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Present with 656 molecules/cell in log phase SD medium.1 Publication

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    2. Yeast chromosome VII
      Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

    External Data

    Dasty 3