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P53237 (LST7_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein LST7
Alternative name(s):
Lethal with SEC thirteen protein 7
Gene names
Name:LST7
Ordered Locus Names:YGR057C
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length242 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Required for the nitrogen-regulated transport of amino acid permeases GAP1 and PUT4 from the Golgi to the cell surface. Ref.4

Miscellaneous

Present with 656 molecules/cell in log phase SD medium.

Sequence caution

The sequence CAA97058.1 differs from that shown. Reason: Erroneous initiation.

The sequence CAA97060.1 differs from that shown. Reason: Erroneous initiation.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 242242Protein LST7
PRO_0000202801

Natural variations

Natural variant41T → I in strain: SK1.

Sequences

Sequence LengthMass (Da)Tools
P53237 [UniParc].

Last modified May 16, 2006. Version 2.
Checksum: 410B0A6E670FACA2

FASTA24228,136
        10         20         30         40         50         60 
MSSTVISLAH FCDKHGPRII SVTQSAEKGT LGEELLVPDY PTESYCESCL LQFPEESTRS 

        70         80         90        100        110        120 
MRCFIEDVPF ITTQYSSIRY QLLNSIIKRA FSEETMIYDN MPFIFFDDLR GLNLVIGFKL 

       130        140        150        160        170        180 
YDENARGNER RYCFILTVDS RSHDDSMKML SEHWNFIIGG FDKMIAYIKN IHKSEFLGKN 

       190        200        210        220        230        240 
KTVENNLETL NNNAFIGSYL RANKSKFGRN LVSLTDDKFL FVRIHKWNSF LLHTVMNENK 


LP 

« Hide

References

« Hide 'large scale' references
[1]"Quantitative trait loci mapped to single-nucleotide resolution in yeast."
Deutschbauer A.M., Davis R.W.
Nat. Genet. 37:1333-1340(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: SK1.
[2]"The nucleotide sequence of Saccharomyces cerevisiae chromosome VII."
Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J., Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M., Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L., Coblenz A., Coglievina M., Coissac E. expand/collapse author list , Defoor E., Del Bino S., Delius H., Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P., Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M., Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A., Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K., Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P., Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E., Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K., Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A., Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S., Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M., Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C., Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M., Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M., Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y., Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L., Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D., Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F., Zaccaria P., Zimmermann M., Zollner A., Kleine K.
Nature 387:81-84(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Control of amino acid permease sorting in the late secretory pathway of Saccharomyces cerevisiae by SEC13, LST4, LST7 and LST8."
Roberg K.J., Bickel S., Rowley N., Kaiser C.A.
Genetics 147:1569-1584(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.
[5]"Sequencing and comparison of yeast species to identify genes and regulatory elements."
Kellis M., Patterson N., Endrizzi M., Birren B.W., Lander E.S.
Nature 423:241-254(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION OF PROBABLE INITIATION SITE.
[6]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DQ115391 Genomic DNA. Translation: AAZ22470.1.
Z72842 Genomic DNA. Translation: CAA97058.1. Different initiation.
Z72843 Genomic DNA. Translation: CAA97060.1. Different initiation.
BK006941 Genomic DNA. Translation: DAA08153.1.
PIRS64351.
RefSeqNP_011571.4. NM_001181186.3.

3D structure databases

ProteinModelPortalP53237.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33302. 14 interactions.
DIPDIP-1424N.
IntActP53237. 2 interactions.
MINTMINT-395024.
STRING4932.YGR057C.

Proteomic databases

PaxDbP53237.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYGR057C; YGR057C; YGR057C.
GeneID852948.
KEGGsce:YGR057C.

Organism-specific databases

CYGDYGR057c.
SGDS000003289. LST7.

Phylogenomic databases

eggNOGNOG324021.
HOGENOMHOG000000953.
OMAFCDKHGP.
OrthoDBEOG7PP5JM.

Enzyme and pathway databases

BioCycYEAST:G3O-30774-MONOMER.

Gene expression databases

GenevestigatorP53237.

Family and domain databases

InterProIPR021713. Folliculin.
[Graphical view]
PfamPF11704. Folliculin. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio972699.

Entry information

Entry nameLST7_YEAST
AccessionPrimary (citable) accession number: P53237
Secondary accession number(s): D6VUJ2, Q45U29
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: May 16, 2006
Last modified: April 16, 2014
This is version 89 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome VII

Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD