Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable serine/threonine-protein kinase FMP48

Gene

FMP48

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei31ATPPROSITE-ProRule annotation1
Active sitei133Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi8 – 16ATPPROSITE-ProRule annotation9

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-30769-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable serine/threonine-protein kinase FMP48 (EC:2.7.11.1)
Alternative name(s):
Found in mitochondrial proteome protein 48
Gene namesi
Name:FMP48
Ordered Locus Names:YGR052W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VII

Organism-specific databases

EuPathDBiFungiDB:YGR052W.
SGDiS000003284. FMP48.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000861131 – 369Probable serine/threonine-protein kinase FMP48Add BLAST369

Proteomic databases

PRIDEiP53233.

PTM databases

iPTMnetiP53233.

Expressioni

Inductioni

By treatment with 8-methoxypsoralen and UVA irradiation.1 Publication

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CDC14Q006842EBI-9664,EBI-4192
HIS4P008152EBI-9664,EBI-8334
TOR1P351693EBI-9664,EBI-19374

Protein-protein interaction databases

BioGridi33297. 68 interactors.
DIPiDIP-5516N.
IntActiP53233. 31 interactors.
MINTiMINT-545426.

Structurei

3D structure databases

ProteinModelPortaliP53233.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 369Protein kinasePROSITE-ProRule annotationAdd BLAST368

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Phylogenomic databases

GeneTreeiENSGT00860000134894.
InParanoidiP53233.
KOiK08286.
OMAiADWGHAI.
OrthoDBiEOG092C4K7T.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P53233-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYTKLRSIQS GTFSTVYKAW STTHNRYVAL KITPKYKTSE ANMKNEYDVM
60 70 80 90 100
KILSSCNPHP NICSMLDFYT DDSYYIMVLE YCECGDLYDF LDIAKSQGSP
110 120 130 140 150
SSPSLIQIDM QKIIKQLCSA ISFAHSLGIA HRDIKPENIL LTINGDIKLA
160 170 180 190 200
DWGHAIQSPK SNDFQIGTDN YRAPETFSGR VSNSCFKKNF DRSSAPLYNT
210 220 230 240 250
YQADYWSLGA TIFYLMFGDC LFRVSKSKKV QHLKNFDEFE KDPFAFIYRK
260 270 280 290 300
YVVPRLSCGY NDEEDLHVSL QHTRQYIWQD LPDIYDVFHL CKIMVDTLLK
310 320 330 340 350
VSNAKERSME NFINEVDSAW NKDSSMDSCF SYQNKIDLFW EQWSVNTETV
360
PAKFQLKNFE KPCLIQDGK
Length:369
Mass (Da):42,823
Last modified:October 1, 1996 - v1
Checksum:i9F34E38FDD3C5892
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z72837 Genomic DNA. Translation: CAA97052.1.
BK006941 Genomic DNA. Translation: DAA08148.1.
PIRiS64346.
RefSeqiNP_011566.1. NM_001181181.1.

Genome annotation databases

EnsemblFungiiYGR052W; YGR052W; YGR052W.
GeneIDi852943.
KEGGisce:YGR052W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z72837 Genomic DNA. Translation: CAA97052.1.
BK006941 Genomic DNA. Translation: DAA08148.1.
PIRiS64346.
RefSeqiNP_011566.1. NM_001181181.1.

3D structure databases

ProteinModelPortaliP53233.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi33297. 68 interactors.
DIPiDIP-5516N.
IntActiP53233. 31 interactors.
MINTiMINT-545426.

PTM databases

iPTMnetiP53233.

Proteomic databases

PRIDEiP53233.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYGR052W; YGR052W; YGR052W.
GeneIDi852943.
KEGGisce:YGR052W.

Organism-specific databases

EuPathDBiFungiDB:YGR052W.
SGDiS000003284. FMP48.

Phylogenomic databases

GeneTreeiENSGT00860000134894.
InParanoidiP53233.
KOiK08286.
OMAiADWGHAI.
OrthoDBiEOG092C4K7T.

Enzyme and pathway databases

BioCyciYEAST:G3O-30769-MONOMER.

Miscellaneous databases

PROiP53233.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiFMP48_YEAST
AccessioniPrimary (citable) accession number: P53233
Secondary accession number(s): D6VUI7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: November 30, 2016
This is version 135 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 339 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.