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Protein

Abhydrolase domain-containing protein IMO32

Gene

IMO32

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Miscellaneous

Present with 7400 molecules/cell in log phase SD medium.1 Publication
The gene contains the nested antisense gene NAG1.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei152Charge relay systemBy similarity1
Active sitei319Charge relay systemBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciYEAST:G3O-30754-MONOMER

Protein family/group databases

ESTHERiyeast-yg1l ABHD11-Acetyl_transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Abhydrolase domain-containing protein IMO32 (EC:3.-.-.-)
Alternative name(s):
Intermediate cleaved by mitochondrial octapeptidyl aminopeptidase protein 32
Gene namesi
Name:IMO32
Ordered Locus Names:YGR031W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VII

Organism-specific databases

EuPathDBiFungiDB:YGR031W
SGDiS000003263 IMO32

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 38MitochondrionAdd BLAST38
PropeptideiPRO_000041079839 – 46Removed in mature form8
ChainiPRO_000020279147 – 342Abhydrolase domain-containing protein IMO32Add BLAST296

Post-translational modificationi

Processed by both the mitochondrial processing peptidase (MPP) and the mitochondrial octapeptidyl aminopeptidase (OCT1).

Proteomic databases

MaxQBiP53219
PaxDbiP53219
PRIDEiP53219

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
PFK26P404334EBI-23124,EBI-1956

Protein-protein interaction databases

BioGridi33276, 40 interactors
DIPiDIP-5604N
IntActiP53219, 8 interactors
MINTiP53219
STRINGi4932.YGR031W

Structurei

3D structure databases

ProteinModelPortaliP53219
SMRiP53219
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini75 – 326AB hydrolase-1Sequence analysisAdd BLAST252

Sequence similaritiesi

Belongs to the AB hydrolase superfamily.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

GeneTreeiENSGT00390000015880
InParanoidiP53219
OMAiHWLHAEN
OrthoDBiEOG092C3NI7

Family and domain databases

Gene3Di3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR029058 AB_hydrolase
IPR000073 AB_hydrolase_1
PfamiView protein in Pfam
PF00561 Abhydrolase_1, 1 hit
SUPFAMiSSF53474 SSF53474, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P53219-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMILGKAGIL AQYGTIYVRQ NTIRNNLSSC IFKQSLCAFH SLAKVLQQKQ
60 70 80 90 100
VPLDLSYDII KRDAVKTGDE GKPRPPIIIL HGLFGNKLNN RSIGRNLNKK
110 120 130 140 150
LGRDVYLLDL RNHGSSPHSS VHNYEVMSED VKHFITKHEL NTNGGPIIIG
160 170 180 190 200
HSMGGKVAMM LVLKNPQLCS MLVCIENAPV SLRPNAEFVE YIKALMEIVN
210 220 230 240 250
DKGKTIRTLK QADEHLAERI GGNELVRRFL LTALKKVKMD NSSSVSSYTF
260 270 280 290 300
EERIPLATLK DAIVKGEIAA WPLDPARERW TRPALFIRAT QSHYVVDEYL
310 320 330 340
PIIGAFFPRF ETRDIDAGHW VNAEKPGECA ESIVDFVERH ED
Length:342
Mass (Da):38,511
Last modified:October 1, 1996 - v1
Checksum:iC6F588A8DDDCA351
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ115390 Genomic DNA Translation: AAZ22445.1
Z72816 Genomic DNA Translation: CAA97019.1
AY557770 Genomic DNA Translation: AAS56096.1
BK006941 Genomic DNA Translation: DAA08127.1
PIRiS64322
RefSeqiNP_011545.1, NM_001181160.1

Genome annotation databases

EnsemblFungiiYGR031W; YGR031W; YGR031W
GeneIDi852919
KEGGisce:YGR031W

Similar proteinsi

Entry informationi

Entry nameiIMO32_YEAST
AccessioniPrimary (citable) accession number: P53219
Secondary accession number(s): D6VUG6, Q45U54
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: March 28, 2018
This is version 130 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health