Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Abhydrolase domain-containing protein IMO32

Gene

IMO32

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei152Charge relay systemBy similarity1
Active sitei319Charge relay systemBy similarity1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciYEAST:G3O-30754-MONOMER.

Protein family/group databases

ESTHERiyeast-yg1l. AlphaBeta_hydrolase.

Names & Taxonomyi

Protein namesi
Recommended name:
Abhydrolase domain-containing protein IMO32 (EC:3.-.-.-)
Alternative name(s):
Intermediate cleaved by mitochondrial octapeptidyl aminopeptidase protein 32
Gene namesi
Name:IMO32
Ordered Locus Names:YGR031W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VII

Organism-specific databases

EuPathDBiFungiDB:YGR031W.
SGDiS000003263. IMO32.

Subcellular locationi

GO - Cellular componenti

  • mitochondrion Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 38MitochondrionAdd BLAST38
PropeptideiPRO_000041079839 – 46Removed in mature form8
ChainiPRO_000020279147 – 342Abhydrolase domain-containing protein IMO32Add BLAST296

Post-translational modificationi

Processed by both the mitochondrial processing peptidase (MPP) and the mitochondrial octapeptidyl aminopeptidase (OCT1).

Proteomic databases

MaxQBiP53219.
PRIDEiP53219.

Interactioni

Protein-protein interaction databases

BioGridi33276. 12 interactors.
DIPiDIP-5604N.
IntActiP53219. 3 interactors.
MINTiMINT-521597.

Structurei

3D structure databases

ProteinModelPortaliP53219.
SMRiP53219.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini75 – 326AB hydrolase-1Sequence analysisAdd BLAST252

Sequence similaritiesi

Belongs to the AB hydrolase superfamily.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

GeneTreeiENSGT00390000015880.
InParanoidiP53219.
OMAiHYIPESS.
OrthoDBiEOG092C3NI7.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000073. AB_hydrolase_1.
[Graphical view]
PfamiPF00561. Abhydrolase_1. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P53219-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMILGKAGIL AQYGTIYVRQ NTIRNNLSSC IFKQSLCAFH SLAKVLQQKQ
60 70 80 90 100
VPLDLSYDII KRDAVKTGDE GKPRPPIIIL HGLFGNKLNN RSIGRNLNKK
110 120 130 140 150
LGRDVYLLDL RNHGSSPHSS VHNYEVMSED VKHFITKHEL NTNGGPIIIG
160 170 180 190 200
HSMGGKVAMM LVLKNPQLCS MLVCIENAPV SLRPNAEFVE YIKALMEIVN
210 220 230 240 250
DKGKTIRTLK QADEHLAERI GGNELVRRFL LTALKKVKMD NSSSVSSYTF
260 270 280 290 300
EERIPLATLK DAIVKGEIAA WPLDPARERW TRPALFIRAT QSHYVVDEYL
310 320 330 340
PIIGAFFPRF ETRDIDAGHW VNAEKPGECA ESIVDFVERH ED
Length:342
Mass (Da):38,511
Last modified:October 1, 1996 - v1
Checksum:iC6F588A8DDDCA351
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ115390 Genomic DNA. Translation: AAZ22445.1.
Z72816 Genomic DNA. Translation: CAA97019.1.
AY557770 Genomic DNA. Translation: AAS56096.1.
BK006941 Genomic DNA. Translation: DAA08127.1.
PIRiS64322.
RefSeqiNP_011545.1. NM_001181160.1.

Genome annotation databases

EnsemblFungiiYGR031W; YGR031W; YGR031W.
GeneIDi852919.
KEGGisce:YGR031W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ115390 Genomic DNA. Translation: AAZ22445.1.
Z72816 Genomic DNA. Translation: CAA97019.1.
AY557770 Genomic DNA. Translation: AAS56096.1.
BK006941 Genomic DNA. Translation: DAA08127.1.
PIRiS64322.
RefSeqiNP_011545.1. NM_001181160.1.

3D structure databases

ProteinModelPortaliP53219.
SMRiP53219.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi33276. 12 interactors.
DIPiDIP-5604N.
IntActiP53219. 3 interactors.
MINTiMINT-521597.

Protein family/group databases

ESTHERiyeast-yg1l. AlphaBeta_hydrolase.

Proteomic databases

MaxQBiP53219.
PRIDEiP53219.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYGR031W; YGR031W; YGR031W.
GeneIDi852919.
KEGGisce:YGR031W.

Organism-specific databases

EuPathDBiFungiDB:YGR031W.
SGDiS000003263. IMO32.

Phylogenomic databases

GeneTreeiENSGT00390000015880.
InParanoidiP53219.
OMAiHYIPESS.
OrthoDBiEOG092C3NI7.

Enzyme and pathway databases

BioCyciYEAST:G3O-30754-MONOMER.

Miscellaneous databases

PROiP53219.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000073. AB_hydrolase_1.
[Graphical view]
PfamiPF00561. Abhydrolase_1. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiIMO32_YEAST
AccessioniPrimary (citable) accession number: P53219
Secondary accession number(s): D6VUG6, Q45U54
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: November 2, 2016
This is version 121 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 7400 molecules/cell in log phase SD medium.1 Publication
The gene contains the nested antisense gene NAG1.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.